Sun, Deli et al. published their research in Chemical Science in 2022 | CAS: 192436-83-2

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Quality Control of 4-Bromo-N-methoxy-N-methylbenzamide

Asymmetric synthesis of aryl/vinyl alkyl carbinol esters via Ni-catalyzed reductive arylation/vinylation of 1-chloro-1-alkanol esters was written by Sun, Deli;Tao, Xianghua;Ma, Guobin;Wang, Jifen;Chen, Yunrong. And the article was included in Chemical Science in 2022.Quality Control of 4-Bromo-N-methoxy-N-methylbenzamide This article mentions the following:

An asym. Ni-catalyzed cross-electrophile coupling approach to prepare enantioenriched aryl/vinyl alkyl carbinol esters RC(O)OC(R1)R2 [R = 4-methylphenyl, iso-Pr, naphthalen-2-yl, etc.; R1 = 4-(methoxycarbonyl)phenyl, 2H-1,3-benzodioxol-5-yl, cyclopent-1-en-1-yl, etc; R2 = Et, 2-phenylethyl, 4-methoxy-4-oxobutyl, etc.] through arylation/vinylation of easily accessible racemic 1-chloro-1-alkanol esters RC(O)OC(Cl)R2 with aryl/vinyl electrophiles R1X (X = Br, I, OTf) was reported. The method features a broad substrate scope as demonstrated by more than 60 examples including the challenging chiral allylic esters. It tolerates a wide array of functional groups including alkenyl, carbonyl and free hydroxyl groups that may not survive in conventional carbonyl reduction and addition methods. The synthetic utility of the present work was showcased by facile preparation of a few key intermediates and the modification of chiral drugs and naturally occurring compounds Finally, an efficient one-pot procedure for this method was described. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Quality Control of 4-Bromo-N-methoxy-N-methylbenzamide).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Quality Control of 4-Bromo-N-methoxy-N-methylbenzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics