Rhodium-Catalyzed C-H Olefination of Aryl Weinreb Amides was written by Wang, Yan;Li, Chao;Li, Yan;Yin, Feng;Wang, Xi-Sheng. And the article was included in Advanced Synthesis & Catalysis in 2013.SDS of cas: 116332-61-7 This article mentions the following:
A rhodium(III)-catalyzed oxidative C-H olefination directed by Weinreb amides, a class of well developed versatile building blocks in organic synthesis, has been developed with air as the terminal oxidant. The reactions proceed with excellent reactivity, good functional group tolerance and high yields. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7SDS of cas: 116332-61-7).
N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.SDS of cas: 116332-61-7
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics