Efficient and general one-pot synthesis of β-chloro-β-trifluoromethylated enones from 3,3,3-trifluoropropyne was written by Jeon, Sung Lan;Kim, Dae Ho;Son, Jang Bae;Jeong, In Howa. And the article was included in Bulletin of the Korean Chemical Society in 2006.Safety of 4-Bromo-N-methoxy-N-methylbenzamide This article mentions the following:
CF3CCH reacted with Weinreb amides in BuLi/THF to give CF3CCl:CHCOR [R = (un)substituted Ph, 1-naphthalenyl, 2-furanyl, cyclohexyl] as E-Z mixtures In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Safety of 4-Bromo-N-methoxy-N-methylbenzamide).
4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Safety of 4-Bromo-N-methoxy-N-methylbenzamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics