Synthesis of Tridentate Chiral Spiro Aminophosphine-Oxazoline Ligands and Application to Asymmetric Hydrogenation of α-Keto Amides was written by Zhang, Feng-Hua;Wang, Chen;Xie, Jian-Hua;Zhou, Qi-Lin. And the article was included in Advanced Synthesis & Catalysis in 2019.Related Products of 106675-70-1 This article mentions the following:
A new type of tridentate chiral spiro aminophosphine-oxazoline ligands (SpiroOAP) were synthesized through four steps. The SpiroOAP ligands are highly efficient for the asym. hydrogenation of α-keto amides, providing a variety of synthetically useful α-hydroxy amides with excellent enantioselectivity (up to 98% ee) and turnover numbers (up to 10,000). In the experiment, the researchers used many compounds, for example, N1,N2-Dimethoxy-N1,N2-dimethyloxalamide (cas: 106675-70-1Related Products of 106675-70-1).
N1,N2-Dimethoxy-N1,N2-dimethyloxalamide (cas: 106675-70-1) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Related Products of 106675-70-1
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics