Correlation between chemical structure and rodent repellency of benzoic acid derivatives was written by Fearn, James E.;DeWitt, James B.. And the article was included in Journal of Agricultural and Food Chemistry in 1965.Computed Properties of C7H5Cl2NO This article mentions the following:
Sixty-five benzoic acid derivatives were either prepared or obtained from com. concerns, tested for rat repellency, and their indexes of repellency computed. The data from these tests were considered anal. for any correlation between chem. structure and rat repellency. The results suggest a qual. relation which is useful in deciding probability of repellency in other compounds In the experiment, the researchers used many compounds, for example, 3,4-Dichlorobenzamide (cas: 2670-38-4Computed Properties of C7H5Cl2NO).
3,4-Dichlorobenzamide (cas: 2670-38-4) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Computed Properties of C7H5Cl2NO
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics