Soundarapandian, Suganthi et al. published their research in Nucleosides, Nucleotides & Nucleic Acids in 2021 | CAS: 2387-23-7

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: 2387-23-7

Molecular encapsulation of berberine and ethidium bromide in anthraquinone-carboxamido-β-cyclodextrin conjugate: supramolecular association with DNA duplex and G-quadruplexes was written by Soundarapandian, Suganthi;Alexander, Aleyamma;Sumohan Pillai, Archana;Enoch, Israel V. M. V.;Yousuf, Sameena. And the article was included in Nucleosides, Nucleotides & Nucleic Acids in 2021.Recommanded Product: 2387-23-7 This article mentions the following:

G-quadruplex DNA in recognized as a potential target for anticancer drugs. In this work, an anthraquinonecarboxamido derivative of β-cyclodextrin (AQCC) is synthesized as a novel DNA binder that further can deliver an addnl. mol. at the target, carrying it in the cavity of modified cyclodextrin. The binding of AQCC with ethidium bromide (EtBr), berberine (Ber), duplex calf-thymus DNA (CT-DNA), quadruplexes, e.g. 5′-AGGGAGGGCGCTGGGAGGAGGG-3′ are studied. The compound acts as a host mol. for the encapsulation of DNA binders viz., EtBr, Ber and enhances their fluorescence due to the encapsulation in its AQCC’s cyclodextrin cavity. The conjugate displays a quenching of fluorescence selectively on the association with CT-DNA and quadruplexes. CT-DNA exhibits dissimilar fluorescence spectra in free- and EtBr-bound forms. In addition, the effect of Ber in binding to the target DNAs is pronounces since the Ber mol. has more affinity to bind to quadruplexes than the duplex. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Recommanded Product: 2387-23-7).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: 2387-23-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics