Stanovnik, B. et al. published their research in Synthesis in 1974 | CAS: 50608-99-6

3-Aminopicolinamide (cas: 50608-99-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Reference of 50608-99-6

Convenient cyclization of o-difunctional heterocycles with N,N-dimethylformamide dimethyl acetal was written by Stanovnik, B.;Tisler, M.. And the article was included in Synthesis in 1974.Reference of 50608-99-6 This article mentions the following:

0-Phenylenediamine cyclized readily with Me2NCH(OMe)2 when heated at 120-30° for 2 hr in DMF to give benzimidazole I (X = NH, X1 = CH). Analogously I (X = S, X1 = CH; X = S, X1 = N; X = NH X1 = N), II, and III (X = N, X1 = CH; X = CH, X1 = ) were prepared In the experiment, the researchers used many compounds, for example, 3-Aminopicolinamide (cas: 50608-99-6Reference of 50608-99-6).

3-Aminopicolinamide (cas: 50608-99-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Reference of 50608-99-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics