One-pot sequential combination of multi-component and multi-catalyst: synthesis of 5-aminobenzofurans from aminophenol and ketene acetals was written by Yang, Cheng-Wen;Bai, Yue-Xia;Zhang, Ni-Tao;Zeng, Cheng-Chu;Hu, Li-Ming;Tian, Hong-Yu. And the article was included in Tetrahedron in 2012.Electric Literature of C13H13NO3S This article mentions the following:
The reaction between p-aminophenols and various ketene acetals in the presence of hypervalent iodine is described. The results show that 2- and 3-substituted 5-sulfonamidobenzofurans, e.g., I, are obtained in moderate to good yields from p-aminophenols and ketene acetals. In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6Electric Literature of C13H13NO3S).
N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Electric Literature of C13H13NO3S
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics