Yoshinaga, Yukako published the artcileStereoinvertive C-C Bond Formation at the Boron-Bound Stereogenic Centers through Copper-Bipyridine-Catalyzed Intramolecular Coupling of α-Aminobenzylboronic Esters, Application of (S)-2-Methylpropane-2-sulfinamide, the main research area is bromobenzamidobenzylic boronate nonracemic preparation; isoindolinone nonracemic preparation; copper bipyridine catalyst intramol Suzuki coupling bromobenzamidobenzylic boronate inversion; bipyridine ligand; carbon stereocenters; copper; enantiospecificity; stereospecific reaction.
Nonracemic α-(bromobenzamido)benzylic boronates such as I (R = Me, n-Pr, PhCH2CH2) and ent-I (R = H) underwent stereospecific intramol. Suzuki coupling reactions in the presence of CuCl2 and 2,2′-bipyridine or 6-phenyl-2,2′-bipyridine and mediated by Cs2CO3 and H2O (and in some cases phenol) in toluene/chloroform to yield nonracemic isoindolinones such as II (R = Me, n-Pr, PhCH2CH2) and ent-II (R = H) with inversion of boronate stereochem.
Angewandte Chemie, International Edition published new progress about Cyclization catalysts, stereoselective. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Application of (S)-2-Methylpropane-2-sulfinamide.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics