Gao, Jianhong published the artcileTotal Synthesis of (+)-Jatrophalactam, Quality Control of 343338-28-3, the main research area is asym total synthesis of jatrophalactam absolute configuration determination; conformationally controlled cyclopropanation asym total synthesis of jatrophalactam; Meldrums acid macrolactam formation asym total synthesis of jatrophalactam; palladium oxidative cyclization asym total synthesis of jatrophalactam.
The first asym. total synthesis of (+)-jatrophalactam was reported, which unambiguously determined the absolute configuration of the titled natural product. The key features entail a conformationally controlled cyclopropanation, a Meldrum’s acid adduct-engaged macrolactam formation, and a Pd(II)-mediated oxidative cyclization.
Organic Letters published new progress about Absolute configuration. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Quality Control of 343338-28-3.
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics