Extraction efficiency of water, ethanol and supercritical carbon dioxide for amide content from fruit of Piper sarmentosum using colorimetry and high performance liquid chromatography was written by Hussain, Khalid;Ismail, Zhari;Sadikun, Amirin;Ibrahim, Pazilah. And the article was included in Journal of the Chemical Society of Pakistan in 2010.COA of Formula: C14H25NO The following contents are mentioned in the article:
Extraction is important for both natural product research and preparation of extracts to be used as raw materials for phytopharmaceuticals. Selection of a suitable solvent as well as type of extraction is prerequisite to prepare extracts enriched with particular type of compounds with peculiar activities. Therefore, the present study aimed to evaluate the extraction efficiency of water, ethanol and supercritical CO2 for amides from fruit of Piper sarmentosum using colorimetry and high performance liquid chromatog. (HPLC). The pulverized fruit material was extracted by reflux using water and ethanol, and supercritical CO2 at 60 °C and operating pressure of 3000, 4000, 6000, 7000 and 8000 psi. The colorimetric anal. indicated that except the water extracts, total amide content in different extracts was not significantly different (P<0.05). Similarly, HPLC anal. using pellitorine, sarmentine and sarmentosine as markers indicated that except water extracts, total content of the markers in different extracts was not significantly different (P<0.05). These results indicate that extraction efficiency of ethanol for amides is comparable to that of supercritical CO2. Hence, ethanol may be used to prepare amide enriched extracts without using costly equipment and operating expertise. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7COA of Formula: C14H25NO).
(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.COA of Formula: C14H25NO
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics