Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 57561-39-4, name is tert-Butyl (2-hydroxyethyl)(methyl)carbamate, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of tert-Butyl (2-hydroxyethyl)(methyl)carbamate
To an ice-cooled solution of tert-butyl 2-hydroxyethyl(methyl)carbamate (300mg, 1 .71 mmol)) in dry CH2CI2 (8.5ml_) under argon was added portion wise Dess-Martin periodinane (762mg, 1.8mmol). Once finished the addition, the reaction mixture was stirred at room temperature for 3h. The mixture was poured into saturated solutions of NaHCOs (50 mL) and Na2S203 (50 mL) and more CH2CI2 (100 mL). It was well-stirred at room temperature for 30 minutes. The organic phase was separated and washed with sat. aq. NaHC03 (1 x 20 mL). It was dried over magnesium sulphate and concentrated to afford the title compound (370 mg, 98%) as colourless oil together with a yellow solid, which was used in the next step without further purification.1H NMR (300 MHz, cdcl3) delta 9.61 (s, 1 H), 3.98 (d, J = 33.9 Hz, 2H), 2.94 (t, J = 10.8 Hz, 3H), 1 .46 (dd, J = 8.2, 6.3 Hz, 9H).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 57561-39-4.
Reference:
Patent; ALMIRALL, S.A.; AIGUADE BOSCH, Jose; GUAL ROIG, Silvia; PRAT QUINONES, Maria; PUIG DURAN, Carlos; WO2013/68552; (2013); A1;,
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