Phosphates and thiophosphates with a heterocyclic substituent. 9. Aza analogs. I. Aza analogs of phthalimide, benzotriazole, and 1,2,3,-benzotriazin-4(3H)-one derivatives was written by Ruefenacht, Kurt. And the article was included in Helvetica Chimica Acta in 1975.Application In Synthesis of 3-Aminopicolinamide This article mentions the following:
Thiophosphates RCH2SP(S)(OR1)2 (I, R = 2,3-pyridinedicarboximido, 3,4-pyridinedicarboximido, 2,3-pyrazinedicarboximido, 1-triazolo[4,5-b]pyridyl, 4-oxopyrido[2,3-e]-1,2,3-triazin-3-yl) were prepared by methylolating RH, chlorinating RCH2OH, and treating RCH2Cl with NH4SP(S)(OMe)2 or KSP(S)(OEt)2. I were approx. equal in toxicity and pesticidal activity to their known analogs. In the experiment, the researchers used many compounds, for example, 3-Aminopicolinamide (cas: 50608-99-6Application In Synthesis of 3-Aminopicolinamide).
3-Aminopicolinamide (cas: 50608-99-6) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Application In Synthesis of 3-Aminopicolinamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics