Effect of pretreated acetic anhydride and reaction conditions on the black by-product in synthesis of tetraacetylethylenediamine was written by Mo, Zai-yong;Liang, Chun-jie;Liu, Ning;Wu, Dan-yun. And the article was included in Yinran Zhuji in 2011.Category: amides-buliding-blocks This article mentions the following:
Tetraacetylethylenediamine was synthesized using diacetylethylenediamine (DAED) with the untreated or pretreated acetic anhydride. The effect of reaction temperature, time and the molar ratio of acetic anhydride to DAED on the absorbency of product were investigated. The results showed that reaction temperature and time had obvious effect on the generation of black byproduct, but the effect of materials ratio was little. Under the condition of temperature 130°C, 6:1 of molar ratio of acetic anhydride to DAED, over 360 min of reaction time, the absorbency of product synthesized by pretreated acetic anhydride, which was pretreated by sulfur trioxide, was less than one fifth of the un-pretreated. Pretreating acetic anhydride was a good method to evidently depress the black byproduct. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Category: amides-buliding-blocks).
N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Category: amides-buliding-blocks
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics