Copper(II)-Catalyzed Enantioselective Intramolecular Carboamination of Alkenes was written by Zeng, Wei;Chemler, Sherry R.. And the article was included in Journal of the American Chemical Society in 2007.HPLC of Formula: 19311-91-2 This article mentions the following:
The enantioselective oxidative cyclizations of γ-alkenyl arenesulfonamides, e.g. I [R1 = H, Me, Ph; R12 = (CH2)4, (CH2)5; R2 = H, Me, Cl, MeO], and a δ-alkenyl arylsulfonamide for the synthesis of nitrogen heterocycles are presented. The reactions are catalyzed by chiral copper(II) complexes, and MnO2 is used as the inexpensive stoichiometric oxidant. A variety of five-membered heterocycles, e.g. II, and a tetrahydroisoquinoline have been synthesized in good to excellent yields with good to excellent levels of enantioselectivity. This is the first reported copper-catalyzed enantioselective carboamination of alkenes. In the experiment, the researchers used many compounds, for example, N,N-Diethylsalicylamide (cas: 19311-91-2HPLC of Formula: 19311-91-2).
N,N-Diethylsalicylamide (cas: 19311-91-2) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.HPLC of Formula: 19311-91-2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics