N,N’-Dimethoxy-N,N’-dimethylethanediamide: a useful α-oxo-N-methoxy-N-methylamide and 1,2-diketone synthon was written by Sibi, Mukund P.;Sharma, Rajiv;Paulson, Kevin L.. And the article was included in Tetrahedron Letters in 1992.COA of Formula: C6H12N2O4 This article mentions the following:
N,N‘-Dimethoxy-N,N‘-dimethylethanediamide (I) on treatment with one to two equivalent of alkyl, aryl, and benzyl Grignard reagents provide α-oxo-N-methoxy-N-methylamides in good to excellent yields and on reaction with excess aryllithiums furnish moderate to good yields of sym. 1,2-diaryl ketones. Thus, I was treated with PhMgBr or 4-MeC6H4Li in THF to give 95% PhCOCONMeOMe or 86% 4-MeC6H4COCOC6H4Me-4, resp. In the experiment, the researchers used many compounds, for example, N1,N2-Dimethoxy-N1,N2-dimethyloxalamide (cas: 106675-70-1COA of Formula: C6H12N2O4).
N1,N2-Dimethoxy-N1,N2-dimethyloxalamide (cas: 106675-70-1) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.COA of Formula: C6H12N2O4
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics