Nickel-catalyzed asymmetric reductive arylation of α-chlorosulfones with aryl halides was written by Sun, Deli;Ma, Guobin;Zhao, Xinluo;Lei, Chuanhu;Gong, Hegui. And the article was included in Chemical Science in 2021.Formula: C9H10BrNO2 This article mentions the following:
An asym. Ni-catalyzed reductive cross-coupling of aryl/heteroaryl halides with racemic α-chlorosulfones to afford enantioenriched sulfones I [R1 = Me, Ph, 2-thienyl, etc.; R2 = Me, n-Bu, Bn, etc.; Ar = 4-MeOOCC6H4, 2-methoxy-pyridin-5-yl, 2-naphthyl, etc.] was reported. The reaction tolerated a variety of functional groups under mild reaction conditions, which complements current methods. The utility of this work was demonstrated by facile late-stage functionalization of com. drugs. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Formula: C9H10BrNO2).
4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C9H10BrNO2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics