Stereoselective Synthesis of Isoxazolidines via Copper-Catalyzed Alkene Diamination was written by Khoder, Zainab M.;Wong, Christina E.;Chemler, Sherry R.. And the article was included in ACS Catalysis in 2017.SDS of cas: 19311-91-2 This article mentions the following:
In the presence of copper(II) 2-ethylhexanoate, 2,6-di-tert-butyl-4-methylpyridine, and MnO2 in 1,2-dichloroethane, (homoallyloxy)carbamates and sulfonamides such as H2C:CHCH2CHPhONHCbz (Cbz = benzyloxycarbonyl) underwent diastereoselective diamination and cyclization reactions with sulfonamides such as TsNH2 (Ts = 4-MeC6H4SO2), arylamines, morpholine, piperidine, and benzamide (in some cases using N,N-diethylsalicylamide as a secondary ligand) to provide 3-(aminomethyl)isoxazolidines such as I in 34-92% yields and in 3:1->20:1 dr (where applicable). Unsaturated carbamates were good substrates for copper-catalyzed diamination. The mild reaction conditions allowed a variety of amines to be used in the diamination reaction. Two (sulfonamidomethyl)isoxazolidines were reduced to yield protected 3,4-diamino alcs. In the experiment, the researchers used many compounds, for example, N,N-Diethylsalicylamide (cas: 19311-91-2SDS of cas: 19311-91-2).
N,N-Diethylsalicylamide (cas: 19311-91-2) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.SDS of cas: 19311-91-2
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics