On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones was written by Sutherell, Charlotte L.;Ley, Steven V.. And the article was included in Synthesis in 2017.Name: 6-Chloro-2-aminobenzamide This article mentions the following:
An improved, scalable synthetic route to the quinazolinone natural product 2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one I (R = H, 6-F, 7-OMe, 8-Me, etc.) is reported. The applicability of this method to analog synthesis and the synthesis of related natural products are explored. Finally, reactivity of the scaffold to a variety of electrophilic reagents, generating products stereoselectively, e.g., II, is reported. In the experiment, the researchers used many compounds, for example, 6-Chloro-2-aminobenzamide (cas: 54166-95-9Name: 6-Chloro-2-aminobenzamide).
6-Chloro-2-aminobenzamide (cas: 54166-95-9) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Name: 6-Chloro-2-aminobenzamide
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics