108468-00-4, Name is 1-(N-Boc-aminomethyl)-4-(aminomethyl)benzene, 108468-00-4, belongs to amides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
EXAMPLE 134 N-(4-tert.butoxycarbonylaminomethyl-phenylmethyl)-3-(4′-trifluoromethylbiphenyl-2-carbonylamino)-benzoic acid amide Prepared analogously to Example 34 from 3-(4′-trifluoromethyl-biphenyl-2-carbonylamino)-benzoic acid, 4-(tert.butoxycarbonyl-aminomethyl)-benzylamine, TBTU and N-ethyldiisopropylamine in dimethylformamide. Yield:89% of theory Rf value:0.70 (silica gel; dichloromethane/ethanol 9:1)
Statistics shows that 1-(N-Boc-aminomethyl)-4-(aminomethyl)benzene is playing an increasingly important role. we look forward to future research findings about 108468-00-4.
Reference:
Patent; Priepke, Henning; Hauel, Norbert; Thomas, Leo; Mark, Michael; Dahmann, Georg; US2002/32238; (2002); A1;,
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