Related Products of 15761-38-3, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 15761-38-3, Name is Boc-Ala-OH, SMILES is C[C@H](NC(OC(C)(C)C)=O)C(O)=O, belongs to amides-buliding-blocks compound. In a article, author is Kannan, Malaichamy, introduce new discover of the category.
Background: Skin delivery and transdermal delivery are key ambitions of the pharmaceutical and cosmetically researchers. Aim: The study aimed to chemically modify well-known polymeric gelling agents in order to boost their topical suitability by fostering their dermal adhesiveness. Methods: Conventional chitosan was modified via amide bound formation with sulfhydryl compound thioglycolic acid. Subsequently, preactivated chitosan conjugate was established by preactivation of chitosan-thioglycolic acid with mercaptonicotinamide being covalently attached via disulfide bond linkage. All conjugates were examined due to their dermal adhesiveness and controlled drug release properties. Results: Preactivated chitosan conjugates Exhibit 7.46-fold dermal adhesiveness on skin due to tensile adhesion strength. Furthermore a 1.9-fold controlled release of Rhodamine123 as model drug was determined in comparison to unmodified chitosan. Conclusion: Taken together, preactivated chitosan gels show a promising platform for topical application. (C) 2017 Elsevier B.V. All rights reserved.
Related Products of 15761-38-3, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 15761-38-3.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics