Formula: C13H13N. Recently I am researching about DIAZO TRANSFER; IMIDAZOLE-1-SULFONYL AZIDE; DIAZOTRANSFER; CYCLOADDITION; ALKYNES; AMINES; SUFEX; SAFE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [NSFC 21672240, NSFC 21421002]; Chinese Academy of SciencesChinese Academy of Sciences [XDB20020300]; CASChinese Academy of Sciences [QYZDB-SSW-SLH028]; Shanghai Sciences and Technology Committee [18JC1415500, 18401933502]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Meng, GY; Guo, TJ; Ma, TC; Zhang, J; Shen, YC; Sharpless, KB; Dong, JJ. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine
Click chemistry is a concept in which modular synthesis is used to rapidly find new molecules with desirable properties(1). Copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) triazole annulation and sulfur(VI) fluoride exchange (SuFEx) catalysis are widely regarded as click reactions(2-4), providing rapid access to their products in yields approaching 100% while being largely orthogonal to other reactions. However, in the case of CuAAC reactions, the availability of azide reagents is limited owing to their potential toxicity and the risk of explosion involved in their preparation. Here we report another reaction to add to the click reaction family: the formation of azides from primary amines, one of the most abundant functional groups(5). The reaction uses just one equivalent of a simple diazotizing species, fluorosulfuryl azide(6-11) (FSO2N3), and enables the preparation of over 1,200 azides on 96-well plates in a safe and practical manner. This reliable transformation is a powerful tool for the CuAAC triazole annulation, the most widely used click reaction at present. This method greatly expands the number of accessible azides and 1,2,3-triazoles and, given the ubiquity of the CuAAC reaction, it should find application in organic synthesis, medicinal chemistry, chemical biology and materials science.
Welcome to talk about 91-00-9, If you have any questions, you can contact Meng, GY; Guo, TJ; Ma, TC; Zhang, J; Shen, YC; Sharpless, KB; Dong, JJ or send Email.. Formula: C13H13N
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics