Application of 144-80-9, These common heterocyclic compound, 144-80-9, name is N-((4-Aminophenyl)sulfonyl)acetamide, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 1N-^S-^-METHOXYPHENYLYTHIENObeta^-DJPYRIMIDINE^- YLAMINO)PHENYLSULFONYL)ACETAMIDE1H-NMR (CDC13/CD3OD/400 MHz): 8.63 (s, IH), 7.88 (d, J = 6.8 Hz, 2H), 7.51 (d, J = 8.9 Hz, 2H), 7.42 (d, J = 8.5 Hz, 2H), 7.34 (s, IH), 7.09 (d, J = 8.9 Hz, 2H), 3.90 (s, 3H), 1.91 (s, 3H).. MS (ES+, m/z): 455.1 (M++l, 100.0).
The synthetic route of 144-80-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SUPERGEN, INC.; WO2008/128072; (2008); A2;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics