《Solvent interception, heterocyclization and desilylation upon NBS-induced sulfamidation of trimethyl(vinyl)silane》 was written by Astakhova, Vera V.; Moskalik, Mikhail Yu.; Shainyan, Bagrat A.. Product Details of 70-55-3This research focused onthree component amidation bromination vinylsilane sulfonamide aziridine preparation; Ritter reaction acetonitrile vinylsilane bromosuccinimide sulfonamide preparation imidazole; oxazocine preparation Ritter reaction acetonitrile bromoalkylsilane. The article conveys some information:
Silylated N-bromoethylsulfonamides, aziridines, imidazoles and oxazocane were prepared by three-component reaction of vinylsilane with brominating agents and sulfonamides with participation of solvent acetonitrile. The reaction of trimethyl(vinyl)silane with sulfonamides in the presence of N-bromosuccinimide was shown to proceed regioselectively in methylene chloride under mild conditions and led to the products of bromosulfamidation in up to 88% yield. The obtained adducts undergo base-promoted dehydrobromination to give 2-trimethylsilyl-N-sulfonyl aziridines in a close to quant. yield. In the reaction with trifluoromethanesulfonamide in acetonitrile or THF, the Ritter-type (solvent-interception) products were obtained and converted to 1-triflyl-2-methyl-5-(trimethylsilyl)-2-imidazoline or 4-triflyl-3-(trimethylsilyl)-1,4-oxazocane in almost quant. yield. In the experimental materials used by the author, we found 4-Methylbenzenesulfonamide(cas: 70-55-3Product Details of 70-55-3)
4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Product Details of 70-55-3
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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics