Castro, Goretti; Wang, Gaoji; Gambino, Tanja; Esteban-Gomez, David; Valencia, Laura; Angelovski, Goran; Platas-Iglesias, Carlos; Perez-Lourido, Paulo published an article in 2021. The article was titled 《Lanthanide(III) Complexes Based on an 18-Membered Macrocycle Containing Acetamide Pendants. Structural Characterization and paraCEST Properties》, and you may find the article in Inorganic Chemistry.HPLC of Formula: 683-57-8 The information in the text is summarized as follows:
We report a detailed investigation of the coordination properties of macrocyclic lanthanide complexes containing a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane scaffold functionalized with four acetamide pendant arms. The X-ray structures of the complexes with the large Ln3+ ions (La and Sm) display 12- and 10-coordinated metal ions, where the coordination sphere is fulfilled by the six N atoms of the macrocycle, the four O atoms of the acetamide pendants, and a bidentate nitrate anion in the La3+ complex. The analogous Yb3+ complex presents, however, a 9-coordinated metal ion because one of the acetamide pendant arms remains uncoordinated. 1H NMR studies indicate that the 10-coordinated form is present in solution throughout the lanthanide series from La to Tb, while the smaller lanthanides form 9-coordinated species. 1H and 89Y NMR studies confirm the presence of this structural change because the two species are present in solution Anal. of the 1H chem. shifts observed for the Tb3+ complex confirms its D2 symmetry in aqueous solution and evidences a highly rhombic magnetic susceptibility tensor. The acetamide resonances of the Pr3+ and Tb3+ complexes provided sizable paraCEST effects, as demonstrated by the corresponding Z-spectra recorded at different temperatures and studies on tube phantoms recorded at 22°C. A 10-coordinated Tb3+ complex shows remarkably a chem. exchange saturation transfer response with a temperature-sensitive chem. shift. In the experimental materials used by the author, we found 2-Bromoacetamide(cas: 683-57-8HPLC of Formula: 683-57-8)
2-Bromoacetamide(cas: 683-57-8) can be used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester. It was aslo used as precursor to dehydropeptidase I inactivator.HPLC of Formula: 683-57-8
Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics