Author: Jessica.F

Swetha, Sathyendran published the artcileAn Umpolung Route to Amides from α-Aminonitriles under Metal-Free Conditions, Related Products of amides-buliding-blocks, the main research area is secondary tertiary amide preparation umpolung; aminonitrile decyanation.

A metal-free, base-mediated decyanation of α-aminonitriles has been developed to synthesize secondary and tertiary amides using O2 or air as an amide oxygen source. Radical scavenging studies disclosed that the cleavage of C-CN bond may proceed via an anionic pathway. The practicality of the work was also demonstrated through an in situ generated α-aminonitriles from corresponding aldehydes and amines to afford amides. The important features of this work include broad functional group compatibility, 41% to 89% product yields, gram-scale synthesis of 2° and 3° amides, broad substrate scope, and an umpolung strategy.

Advanced Synthesis & Catalysis published new progress about Amides, secondary Role: SPN (Synthetic Preparation), PREP (Preparation). 7465-88-5 belongs to class amides-buliding-blocks, name is 4-Methoxy-N-phenylbenzamide, and the molecular formula is C14H13NO2, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xu, Xu-Dong published the artcileMetal-Free Regioselective Radical Cyclization of 1,6-Enynes with Carbonyl Compounds, Product Details of C2H5NO, the main research area is enyne carbonyl regioselective radical cyclization.

A regioselective cyclization of 1,6-enynes is reported by a tert-Bu hydroperoxide (TBHP)-mediated, one-pot, cascade reaction with com. available carbonyl compounds under metal- and additive-free conditions. The reaction scope includes both 1,6-enynes and carbonyl compounds A possible cascade reaction mechanism, consisting of acyl radical addition, intramol. cyclization, and hydrogen abstraction, is proposed.

ACS Sustainable Chemistry & Engineering published new progress about Alkenynes Role: RCT (Reactant), RACT (Reactant or Reagent) (1,6-Enynes). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Product Details of C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ding, Wenwu published the artcileCharacterization of volatile compounds between industrial closed fermentation and traditional open fermentation doubanjiang-meju, Application of N-Methylformamide, the main research area is alc ester volatile compound doubanjiang meju closed open fermentation.

Doubanjiang-meju has been used as an intermediate for producing Pixian Douban (PXDB) and contributes significantly to its flavor. In this study, a profiling anal. of volatile compounds in open fermented doubanjiang-meju (OFD) and closed fermented doubanjiang-meju (CFD) was performed with gas chromatog.-mass spectrometry (GC-MS) and gas chromatog.-olfactometry (GC-O). A total of 42 and 50 volatile compounds were identified in the OFD and CFD, resp. Compared with the OFD, more diversity and higher concentrations of alcs. and esters were found in the CFD. Ten and 12 volatile compounds were finally identified as the major aroma-active compounds in the OFD and CFD, resp., by the combined anal. of aroma intensity values and odor activity values (OAVs). The CFD had significantly stronger umami and soy sauce flavor but weaker beany when compared with the OFD (p < 0.05) by quant. descriptive anal. (QDA), which were basically consistent with intensity values of aroma compounds obtained with GC-O. The results indicated that the CFD had better characteristics of volatile compounds than those of the OFD, which provided a basis of further study for the closed fermentation process of tank fermenter. European Food Research and Technology published new progress about Acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Dong, Yi published the artcileRhodium(III)-catalyzed sulfonamide directed ortho C-H carbenoid functionalization via metal carbene migratory insertion, HPLC of Formula: 35203-88-4, the main research area is diazoacetate arylsulfonyl acetamide preparation rhodium catalyst regioselective migratory insertion; acetylsulfamoyl arylacetate preparation.

A rhodium(III)-catalyzed sulfonamide directed ortho C-H carbenoid functionalization was developed with good yields. This method was attractive due to its broad substrate scope and enabled derivation of diverse biol. active sulfonamide structures and late-stage modification of sulfa drugs.

Chemical Communications (Cambridge, United Kingdom) published new progress about 1,3-Dicarbonyl compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 35203-88-4 belongs to class amides-buliding-blocks, name is 3-Acetylbenzenesulfonamide, and the molecular formula is C8H9NO3S, HPLC of Formula: 35203-88-4.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Perry, Carolina Trindade published the artcileAmides as cryoprotectants for the freezing of Brycon orbignyanus sperm, Safety of N-Methylformamide, the main research area is Brycon sperm freezing amide cryoprotectant.

The objective of this study was to evaluate the use of different amides as an alternative for the cryopreservation of sperm from the endangered species, Bryconorbignyamus, an important fish for aquaculture in Brazil. The cryoprotectants which were combined with Beltsville Thawing Solution extender, each at the concentrations of 2.5%, 5%, 7.5%, and 10%, were as follows: (1) dimethylacetamide (DMA), (2) DMF (DMF), and (3) methylformamide (MF). The cyoprotectant methylglycol (MG, 10%) was used as a control group. Therefore, 13 treatment groups were performed. In order to assess DNA fragmentation index, lipid peroxidation, cell integrity, integrity of plasma membrane, membrane fluidity, mitochondrial functionality, and reactive oxygen species, flow cytometry was used. The best results were obtained with 7.5% DMF, among all the amides tested, with sperm motility (66%) significantly higher than the other cryoprotectants evaluated (P < .05). It also exhibited high membrane integrity (84.5%) and cell integrity (98.7%), and low membrane fluidity (20.3%) (P < .05). MG (10%) exhibited only 38% motility, lower mitochondrial protection (39.8%), and higher DNA fragmentation index (0.07), despite the high membrane integrity observed (85.6%). The DMF concentration of 7.5% demonstrated greater protection of sperm function and cellular structure, and is therefore recommended for the cryopreservation of B. orbignyamus spermatozoa. Aquaculture published new progress about Amides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Safety of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Srinivasulu, A. published the artcileCopper-Catalyzed N-Alkyl Formamide Activation: Tandem Oxidative Coupling Approach for the Construction of C-N and C-O Bonds to Synthesize 3-Alkyl-1,3-Benzoxazine-2,4-Dione and 4-Methylene-3-Alkyl-1,3-Benzoxazine-2-One Derivatives, Application of N-Methylformamide, the main research area is alkyl benzoxazine dione preparation; salicyaldehyde alkyl formamide activation tandem oxidative coupling copper catalyst; methylene alkyl dihydrobenzoxazineone preparation; hydroxy acetophenone alkyl formamide activation tandem oxidative coupling copper.

Synthesis of 3,4-dihydro-2H-benzo[e][1,3]oxazin-2-ones I [R = Me, Et; R1= H, 6-Me, 7-OMe, etc.; X = O, CH2] via N-alkyl formamide activation by using copper/oxidant system via tandem oxidative coupling with salicyaldehydes/hydroxy acetophenones constructing C-N/C-O bond was reported. This protocol elucidated a method for the synthesis of pharmaceutically interested 3-alkyl-1,3-benzoxazine-2,4-dione and 1,3-methylene-3-alkyl-benzoxazine-2-one derivatives without the aid of toxic chems. such as phosgene or its derivatives

Advanced Synthesis & Catalysis published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent) (o-hydroxy). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Dudko, Volodymyr published the artcileOsmotic delamination: Forceless alternative for production of nanosheets now in highly polar and aprotic solvents, Name: N-Methylformamide, the main research area is osmotic delamination nanosheet polar aprotic solvent.

Repulsive osmotic delamination is thermodynamically allowed “”dissolution”” of two-dimensional (2D) materials and therefore represents an attractive alternative to liquid-phase exfoliation to obtain strictly monolayered nanosheets with an appreciable aspect ratio with quant. yield. However, osmotic delamination was so far restricted to aqueous media, severely limiting the range of accessible 2D materials. Alkali-metal intercalation compounds of MoS2 or graphite are excluded because they cannot tolerate even traces of water. We now succeeded in extending osmotic delamination to polar and aprotic organic solvents. Upon complexation of interlayer cations of synthetic hectorite clay by crown ethers, either 15-crown-5 or 18-crown-6, steric pressure is exerted, which helps in reaching the threshold separation required to trigger osmotic delamination based on translational entropy. This way, complete delamination in water-free solvents like aprotic ethylene and propylene carbonate, N-methylformamide, N-methylacetamide, and glycerol carbonate was achieved.

Langmuir published new progress about Alkali metals Role: TEM (Technical or Engineered Material Use), USES (Uses). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Name: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sikorski, Patryk published the artcileSolid-liquid equilibria in systems consisting of potassium pseudohalides and amides, Recommanded Product: N-Methylformamide, the main research area is potassium pseudohalide amide solid liquid equilibrium.

Within the framework of this research, we measured solid-liquid equilibrium diagrams of binary systems of potassium thiocyanate or potassium selenocyanate in {formamide, or N-methylformamide, or N,N-dimethylformamide} as functions of temperature, using the cloud-point and DSC techniques over the full concentration range. The temperatures varied approx. between 220 and 450 K. As a next step, we determined limited solubility data for the potassium cyanate with {formamide or N-methylformamide}. We then correlated the data by the thermodn. solubility equations with the solute activity coefficients represented by the Redlich-Kister model. Finally, we proceeded to calculate the coordinates of the invariant points, and discussed the observed phenomena.

Journal of Molecular Liquids published new progress about Amides Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Khachatrian, Artashes A. published the artcileEffect of cation structure on the formation of hydrogen bond between ionic liquids and solute molecules, Formula: C2H5NO, the main research area is cation structure formation hydrogen bond ionic liquid solute mol.

In this work, we have studied the thermochem. of the hydrogen bond formation between ionic liquids and solute mols. The solution enthalpies of several organic compounds (benzene, acetone, 3-picoline dimethylsulfoxide, formamide, N-methylformamide, acetamide, N-methylacetamide) in the series of ionic liquids with common anion bis(trifluoromethanesulfonyl)imide and different cations (1-butyl-3-methylimidazolium [BMIM][NTf2], 1-butyl-1-methylpyrrolidinium [BMPYR][NTf2], 1-butylpyridinium [BPY][NTf2], 1-butyl-1-methylpiperidinium [BMPIP][NTf2], trimethylpropylammonium [TMPAm][NTf2]) were measured by solution calorimetry at infinite dilution The enthalpies of hydrogen bond between solutes and ionic liquids were determined by the previously proposed approach. The hydrogen bond enthalpies were correlated with the proton acceptor ability of ionic liquids from the Kamlet-Abboud-Taft equation and the proton donor ability of amides from the Abraham model. The proton donor ability and hydrogen bond reorganization of studied ionic liquids was analyzed. The formation of the hydrogen bond complexes of linear amides with ionic liquids with different compositions was shown. The effect of the ionic liquid structure on the strength of the hydrogen bond of linear amides with ionic liquids has been established.

Journal of Molecular Liquids published new progress about Amides Role: PEP (Physical, Engineering or Chemical Process), PROC (Process). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Protesescu, Loredana published the artcileColloidal nano-MOFs nucleate and stabilize ultra-small quantum dots of lead bromide perovskites, Recommanded Product: N-Methylformamide, the main research area is lead bromide perovskites nanoparticle metal organic framework quantum dot.

The development of synthetic routes to access stable, ultra-small (i.e. <5 nm) lead halide perovskite (LHP) quantum dots (QDs) is of fundamental and technol. interest. The considerable challenges include the high solubility of the ionic LHPs in polar solvents and aggregation to form larger particles. Here, we demonstrate a simple and effective host-guest strategy for preparing ultra-small lead bromide perovskite QDs through the use of nano-sized MOFs that function as nucleating and host sites. Cr3O(OH)(H2O)2(terephthalate)3 (Cr-MIL-101), made of large mesopore-sized pseudo-spherical cages, allows fast and efficient diffusion of perovskite precursors within its pores, and promotes the formation of stable, ∼3 nm-wide lead bromide perovskite QDs. CsPbBr3, MAPbBr3 (MA+ = methylammonium), and (FA)PbBr3 (FA+ = formamidinium) QDs exhibit significantly blue-shifted emission maxima at 440 nm, 446 nm, and 450 nm, resp., as expected for strongly confined perovskite QDs. Optical characterization and composite modeling confirm that the APbBr3 (A = Cs, MA, FA) QDs owe their stability within the MIL-101 nanocrystals to both short- and long-range interfacial interactions with the MOF pore walls. Chemical Science published new progress about Carboxylic acids Role: TEM (Technical or Engineered Material Use), USES (Uses). 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics