Author: Jessica.F

On August 31, 2013, Karimi Zarchi, Mohammad Ali; Tarabsaz, Ali published an article.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the article was Versatile and efficient method for synthesis of β-halohydrins via regioselective ring opening reaction of epoxides using cross-linked poly (4-vinylpyridine) supported HCl and HBr under solvent-free conditions. And the article contained the following:

In this paper a versatile and efficient method for synthesis of vicinal halohydrins via regioselective ring opening of epoxides by using polymer-supported HCl and HBr under solvent-free conditions is described. The regioselective ring opening of various epoxides is achieved under mild and solvent-free conditions by using crosslinked poly(4-vinylpyridine)-supported hydrochloric acid, [P4-VP]HCl and crosslinked poly(4-vinylpyridine)-supported hydrobromic acid, [P4-VP]HBr, under heterogeneous conditions. [P4-VP]HCl and [P4-VP]HBr act as both solid proton source and as nucleophile and consequently, the corresponding β-halohydrin product is prepared [P4-VP]HCl and [P4-VP]HBr can be easily regenerated and reused several cycles without their activity changing appreciably. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to vinylpyridine polymer hydrobromide hydrochloride catalyst ring opening epoxide, halohydrin production vinylpyridine polymer hydrobromide hydrochloride catalyst, Plastics Manufacture and Processing: Chemical Properties Of Resins and other aspects.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 31, 2021, Wang, Guoying; Li, Guoxue; Chang, Jiali; Kong, Yilin; Jiang, Tao; Wang, Jiani; Yuan, Jing published an article.Recommanded Product: 144-80-9 The title of the article was Enrichment of antibiotic resistance genes after sheep manure aerobic heap composting. And the article contained the following:

In this study, physio-chem. properties, 45 antibiotics, 6 heavy metals, 42 antibiotic resistance genes (ARGs), 3 mobile genetic elements, and the bacterial community structure were investigated to analyze the fate of ARGs during sheep manure aerobic heap composting. Results showed that sheep manure heap composting could produce mature compost. The degradation processes reduced the total antibiotics content by 85%. The abundance of ARGs and mobile genetic elements (MGEs) were enriched 9-fold, with the major increases to sul and tet genes (sulI, sulII, tetQ, and tetX). Tetracycline and sulfonamide resistance genes were the most abundant ARGs after composting (more than 88% of all genes). The genes tetA, tetX and sulI were related to the most diverse bacteria that were most able to proliferate during heap composting. Therefore, sulI and tetX are the major ARGs to be controlled, and Actinobacteria and Bacteroidetes may be the major host bacteria. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Recommanded Product: 144-80-9

The Article related to antibiotic resistance gene sheep manure aerobic heap composting, antibiotic, antibiotic resistance genes, bacterial community structures, heap composting, sheep manure, Waste Treatment and Disposal: Physical Treatment Of Aqueous Wastes and other aspects.Recommanded Product: 144-80-9

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Amide – an overview | ScienceDirect Topics

Hardia, Sunita Patel; Khadikar, Padmakar V. published an article in 2008, the title of the article was QSAR study on diuretic activity of sulphonamides using force-constant.SDS of cas: 97-09-6 And the article contains the following content:

This is the first report on the use of valence force constant for modeling diuretic activity of benzene sulfonamides. The authors used both the regular as well as robust multiple regression analyses for this purpose. Statistically significant models are obtained in multi-parametric regression anal. upon introduction of indicator parameters. The results are discussed critically using variety of statistics. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).SDS of cas: 97-09-6

The Article related to qsar diuretic sulfonamide force, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.SDS of cas: 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 5, 2021, Laurence, Christian; Mansour, Sergui; Vuluga, Daniela; Planchat, Aurelien; Legros, Julien published an article.Synthetic Route of 685-91-6 The title of the article was Hydrogen-Bond Acceptance of Solvents: A 19F Solvatomagnetic β1 Database to Replace Solvatochromic and Solvatovibrational Scales. And the article contained the following:

A variety of physicochem. properties and several hydrogen-bond donors have been used to define methods and to build scales aiming at measuring the hydrogen-bond acceptance of solvents. There is a great deal of confusion in these scales and methods. Solvatochromic, solvatocalorimetric, solvatovibrational, and 19F solvatomagnetic comparison methods are critically reviewed. Only two methods, the solvatomagnetic and the solvatocalorimetric ones, are able to yield reliable solvent hydrogen-bond acceptance scales. The solvatomagnetic β1 scale defined from the 19F chem. shift of 4-fluorophenol is extended to many solvents including ionic liquids and green solvents. The results for about 240 hydrogen-bond acceptor solvents are organized in a numerical β1 database. The comparison of β1 with solvatochromic scales highlights their shortcomings, in particular for the important class of amphiprotic solvents. Therefore, the use of the 19F solvatomagnetic comparison method and of the solvatomagnetic β1 scale is recommended in solvent effect studies. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Synthetic Route of 685-91-6

The Article related to solvent hydrogen bond acceptor solvatomagnetic scale database, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Synthetic Route of 685-91-6

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Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Nazli, Ibrahim Hanif; Celepci, Duygu Barut; Yakali, Guel; Topkaya, Derya; Ayguen, Muhittin; Alp, Serap published an article in 2018, the title of the article was Spectroscopic, structural and density functional theory (DFT) studies of two oxazol-5-one derivatives.Category: amides-buliding-blocks And the article contains the following content:

In this study, two oxazol-5-one derivatives, C20H20N2O2 (1) and C21H22N2O2 (2), were synthesized by getting condensed p-N,N-diethylaminobenzaldehyde with two presented hippuric acid derivatives and in further studies they were analyzed spectrochem. Mol. and crystal structures of the compounds were determined by single-crystal X-ray diffraction and the results revealed that the mol. packing of the crystal structures were stabilized by weak intraand intermol. interactions also with C-O···π, C-H···π and π···π stacking interactions. Computational studies were also performed using DFT method at B3LYP/6-311G(d,p) level of theory. Vibrational modes and chem. shifts were calculated and compared with the exptl. data. In addition, frontier MOs and mol. electrostatic potential surfaces were simulated. The calculated results show that the optimized geometries can well reproduce the crystal structure. Purpose of this study was to survey the effects of the reactants, which were condensed with each other to produce oxazol-5-one, upon the characteristic properties and crystal forms of the final oxazol-5-one. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Category: amides-buliding-blocks

The Article related to oxazolone condensation reaction hydrogen bond crystal structure, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 3, 2015, Fujiki, Hironao; Suzuki, Takanori published a patent.Category: amides-buliding-blocks The title of the patent was Conductive composition, conductive composition production method, anti-static resin composition and antistatic resin film. And the patent contained the following:

A transparent conductive film with fewer problems originating from amine compounds is provided using a conductive composition stably and pseudo-solubly dispersed in a solvent consisting mainly of an organic solvent. This invention relates to: a conductive composition which is pseudo-solubly dispersed in a solvent consisting mainly of an organic solvent and which contains (a) a π-conjugated conductive polymer, (b) polyanions doping the π-conjugated conductive polymer (a), and (c) a reaction product of those anions of the polyanions (b) that were not needed for doping, and an oxirane group- and/or oxetane group-containing organic compound; a production method of said conductive composition; an antistatic resin composition formed by mixing said conductive composition and a resin solution dissolved in an organic solvent; and antistatic resin film formed by curing said antistatic resin composition The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Category: amides-buliding-blocks

The Article related to conductive composition production antistatic resin antistatic film, Electric Phenomena: Conductors, Semiconductors, Resistors, Contacts and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 25, 2007, Yu, Xuhui; Ge, Hongyan; Zhang, Lei; Song, Han; Yu, Ying; Wang, Yuhong published an article.Synthetic Route of 456-12-2 The title of the article was Expressions of IL-12 and IL-18 in patients with acute optic neuritis before and after methylprednisolone pulse therapy. And the article contained the following:

The expressions of interleukin-12 (IL-12) and interleukin-18 (IL-18) and the relationship between IL-12 and IL-18 in acute optic neuritis (AON) before and after methylprednisolone pulse therapy (MPPT) were investigated. ELISA was employed to determine the expressions of IL-12 and IL-18 in serum in 27 patients with AON before and after MPPT. RT-PCR anal. was employed to demonstrate the expressions of IL-12 and IL-18 receptors in peripheral lymphocytes. The serum level of IL-12 was decreased from (45.6±12.2) ng/L to (17.1±4.7) ng/L after MPPT (P < 0.01), and that of IL-18 was decreased from (157.5±39.3) ng/L to (126.2±22.6) ng/L (P < 0.05). The expression of IL12R mRNA was decreased after MPPT too (0.2948 vs. 0.1507, P < 0.05), and so was that of IL18R mRNA (0.5352 vs. 0.2843, P < 0.05). The expressions of IL-12 and IL-18 as well as those of their receptors were pos. correlated. Methylprednisolone could exert its important antiphlogistic action against AON by inhibiting the expressions of the proinflammatory cytokines, IL-2 and IL-18. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Synthetic Route of 456-12-2

The Article related to interleukin il12 il18 optic neuritis methylprednisolone antiinflammatory, Mammalian Hormones: Corticosteroid, Gonadal, and Placental Hormones and other aspects.Synthetic Route of 456-12-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Nayaka, Swapna r.; Sabari, Anand j. v.; Shareef, Shaik mabu; Usha, N. s. published an article in 2020, the title of the article was Gas chromatography-mass spectroscopy [Gc-Ms] analysis and phytochemical screening for bioactive compounds in Caulerpapeltata(Greenalga).COA of Formula: C6H13NO And the article contains the following content:

Seaweeds (Marine macroalgae) area large group of marine organisms containing important phytochem. constituents with various biol. activities. They are potentially prolific sources of highly bioactivese condary metabolites, which manifest many of the rapeutic effects like anti-cancer, anti-oxidant, anti-inflammatory and anti-diabetic activities. Seaweeds are used by many Asian cultures for traditional medicine preparations The Caulerpapeltata was collected from Rameshwaram coastal area it was shade dried, made in to powder using standardized procedure to get Caulerpa peltata Methanolic Extract (CPME). The phytochems. and Gas Chromatog.-Mass Spectrometry (GC-MS) anal. was done on prepared CPME for identifying the bioactive compounds Phytochem. in vestigation suggests that the Caulerpa peltata exhibited the presence of phytochems. like Alkaloids, Carbohydrates, Phytosterols, Saponins and Diterpenes, which may contribute to its biol. activities. GC-MS anal. showed 28 variety of compounds, among which Dibutylphthalate, n-hexadecanoic acid, and 1,2-Benzenedic arboxylic acid was found in high percentage. The phytochem. studies and the compounds available in GC-MS showed that the Caulerpapeltata contain important bio active compounds, which may have anti-microbial, anti-fungal and anti-canceractivity. Further research is needed for finding its use in development of new pharmaceutical agent and its safe consumption by human for various health benefits. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).COA of Formula: C6H13NO

The Article related to cauler papeltata bioactive compound phytochem gas chromatog mass spectroscopy, Microbial, Algal, and Fungal Biochemistry: Composition and Products and other aspects.COA of Formula: C6H13NO

Referemce:
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Amide – an overview | ScienceDirect Topics

Zhang, Chuhui; Maness, J. Clark; Cuthbertson, Amy A.; Kimura, Susana Y.; Liberatore, Hannah K.; Richardson, Susan D.; Stanford, Benjamin D.; Sun, Mei; Knappe, Detlef R. U. published an article in 2020, the title of the article was Treating water containing elevated bromide and iodide levels with granular activated carbon and free chlorine: impacts on disinfection byproduct formation and calculated toxicity.Electric Literature of 79-07-2 And the article contains the following content:

We evaluated the efficacy of granular activated carbon (GAC) adsorption for mitigating formation of chlorine disinfection byproducts (DBPs) in water with a wide range of bromide (20-1000μg L-1) and iodide (<5-100μg L-1) concentrations GAC effectiveness was assessed by determining speciated total organic halogen (TOX), 70 DBPs, and calculated cyto- and genotoxicity. Overall, GAC treatment effectively lowered formation of TOX and the majority of targeted DBPs over the evaluated service time (>30 000 bed volumes). In the GAC influent, total organic bromine increased from 10 to 84% of TOX as bromide levels increased from 20 to 1000μg L-1. Dissolved organic carbon (DOC) removal by GAC increased the bromide-to-DOC (Br/DOC) concentration ratio in GAC effluent relative to influent. As a result, bromine incorporation into DBPs increased after GAC treatment, especially at early GAC service times and low bromide levels. Total organic iodine was <3.5% of TOX, and iodo-DBP formation was low because elevated iodide was only evaluated in the presence of high bromide and free chlorine, a scenario that favors iodate formation. Although trihalomethanes (THMs) and haloacetic acids (HAAs) consistently formed at the highest molar concentrations, they were not major contributors to calculated cyto- and genotoxicity. Principal contributors to calculated cytotoxicity included haloacetaldehydes (HALs), haloacetamides (HAMs), and haloacetonitriles (HANs), while the main drivers of genotoxicity were HALs, HAMs, HANs, and halonitromethanes (HNMs) despite lower concentrations Because bromine incorporation into DBPs increased nonlinearly with increasing Br/DOC concentration ratios, GAC more effectively controlled calculated toxicity at elevated bromide levels. Calculated cyto- and genotoxicity did not vary strongly with GAC service life, suggesting that GAC treatment can effectively lower calculated toxicity over long periods of operation. The majority of TOX remained unknown (>50%) in all samples despite the quantification of 70 DBPs targeted in this study, highlighting the need to assess toxicity associated with unknown DBPs. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Electric Literature of 79-07-2

The Article related to bromide iodide activated carbon chlorine disinfection byproduct formation toxicity, Water: Water Purification (Including Treatment For Industrial Uses) and other aspects.Electric Literature of 79-07-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 1, 2022, Dabrowska, Aleksandra M.; Mech-Warda, Paulina; Wera, Michal; Domzalska, Marta; Makowski, Mariusz; Chylewska, Agnieszka published an article.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Prototropic tautomerism of (E)-N-((4-((2-hydroxy-5-methoxybenzylidene) amino)phenyl)sulfonyl)acetamide and its coordination abilities towards Ru, Rh, and Ir trivalent metal ions. And the article contained the following:

The Schiff base (E)-N-((4-((2-hydroxy-5-methoxybenzylidene)amino)phenyl)sulfonyl) acetamide (ScB-SAM) has been synthesized bytheir condensation at room temperature in ethanol. X-ray crystallog. anal. revealed that the keto-enol tautomerism of its solid state exists as a complex equilibrium system that is stabilized intramol. hydrogen bond. The enol, keto and mixed enol-zwitterionic forms were observed in the crystal structure. The crystallog. results were supported by ATR, and UV-Vis. Phys. properties were determined in different polar and nonpolar solvents and solid state. All above exptl. results were then compared with DFT calculations Addnl., the stabilities of the trivalent: iridium, rhodium and ruthenium ions complexes with ScB-SAM have also been investigated by spectrophotometric titration methods in water. The data showed that the examined coordination compounds were stable in solution based on the values of their stability constants found. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to salicylideneaniline schiff base preparation electronic structure metal coordination stability, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics