Author: Jessica.F

On February 21, 2020, Nanda, Tanmayee; Ravikumar, P. C. published an article.Quality Control of 1,3-Diphenylurea The title of the article was A Palladium-Catalyzed Cascade C-C Activation of Cyclopropenone and Carbonylative Amination: Easy Access to Highly Functionalized Maleimide Derivatives. And the article contained the following:

We describe herein the first report on palladium-catalyzed C-C bond activation of cyclopropenone and concomitant carbonylative amination to produce maleimides. The interesting aspect of this reaction is that the sacrificial elimination of carbon monoxide from the substrate is efficiently recaptured by one of the intermediates in the catalytic cycle for the formation of maleimides. 18O isotopic studies confirmed that the source of carbon monoxide is from cyclopropenone. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Quality Control of 1,3-Diphenylurea

The Article related to palladium catalyzed cascade decarbonylation carbonylative amination cyclopropenone, maleimide synthesis, Heterocyclic Compounds (One Hetero Atom): Pyrroles and Pyrrolizines and other aspects.Quality Control of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 19, 2020, Sandler, Isolde; Larik, Fayaz Ali; Mallo, Neil; Beves, Jonathon E.; Ho, Junming published an article.Quality Control of 1,3-Diphenylurea The title of the article was Anion Binding Affinity: Acidity versus Conformational Effects. And the article contained the following:

High-level quantum chem. calculations were used to elucidate the gas- and solution-phase conformational equilibrium for a series of sym. substituted (thio)ureas, (thio)squaramides, and croconamides. Gas-phase calculations predict that the thermodn. conformer of many of these anion receptors is not the dual-hydrogen-bond-facilitating anti-anti conformer as is commonly assumed. For N,N’-diaryl thiosquaramides and croconamides, the syn-syn conformer is typically the predominant conformer. Solution-phase calculations show that the anti-anti conformer is increasingly stabilized as the polarity of the solvent increases. However, the syn-syn conformer remains the lowest energy conformation for croconamides. These predictions are used to explain the acidity vs. chloride binding affinity correlations recently reported for some of these compounds The chloride binding constants for thioureas and croconamides are significantly lower than expected on the basis of their pKa values, and this may be due in part to the need for these receptors to reorganize into the anti-anti conformer. Exptl. NMR nuclear Overhauser effect (NOE) measurements of an asym. substituted squaramide and its thio analog are consistent with the syn-syn conformation being predominant at 298 K. The conformational equilibrium should therefore be an important consideration for the design and development of future anion receptors and organocatalysts. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Quality Control of 1,3-Diphenylurea

The Article related to urea thiourea squaramide thiosquaramide croconamide, receptor anion binding affinity acidity conformational effect, Physical Organic Chemistry: Other Reactions, Processes, and Spectra and other aspects.Quality Control of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Krais, Annette M.; Essig, Julie Y.; Gren, Louise; Vogs, Carolina; Assarsson, Eva; Dierschke, Katrin; Nielsen, Joern; Strandberg, Bo; Pagels, Joakim; Broberg, Karin; Lindh, Christian H.; Gudmundsson, Anders; Wierzbicka, Aneta published an article in 2021, the title of the article was Biomarkers after controlled inhalation exposure to exhaust from Hydrogenated vegetable oil (HVO).Recommanded Product: 27115-50-0 And the article contains the following content:

Hydrogenated vegetable oil (HVO) is a renewable diesel fuel used to replace petroleum diesel. The organic compounds in HVO are poorly characterized; therefore, toxicol. properties could be different from petroleum diesel exhaust. The aim of this study was to evaluate the exposure and effective biomarkers in 18 individuals after short-term (3 h) exposure to HVO exhaust and petroleum diesel exhaust fumes. Liquid chromatog. tandem mass spectrometry was used to analyze urinary biomarkers. A proximity extension assay was used for the measurement of inflammatory proteins in plasma samples. Short-term (3 h) exposure to HVO exhaust (PM1 ~1μg/m3 and ~90μg/m3 for vehicles with and without exhaust aftertreatment systems, resp.) did not increase any exposure biomarker, whereas petroleum diesel exhaust (PM1 ~300μg/m3) increased urinary 4-MHA, a biomarker for p-xylene. HVO exhaust from the vehicle without exhaust aftertreatment system increased urinary 4-HNE-MA, a biomarker for lipid peroxidation, from 64 ng/mL urine (before exposure) to 141 ng/mL (24 h after exposure, p < 0.001). There was no differential expression of plasma inflammatory proteins between the HVO exhaust and control exposure group. In conclusion, short-term exposure to low concentrations of HVO exhaust did not increase urinary exposure biomarkers, but caused a slight increase in lipid peroxidation associated with the particle fraction. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Recommanded Product: 27115-50-0

The Article related to hydrogenated vegetable oil inhalation exposure biomarker, hvo, aerosol, biomarkers, exposure studies, lipid peroxidation, renewable diesel, Fossil Fuels, Derivatives, and Related Products: Crude-Oil Refining and other aspects.Recommanded Product: 27115-50-0

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 31, 2020, Baulina, T. V.; Kudryavtsev, I. Yu.; Artem’ev, A. V.; Bagryanskaya, I. Yu.; Pasechnik, M. P.; Brel, V. K. published an article.Reference of 2-Chloroacetamide The title of the article was Synthesis, Molecular, and Crystal Structure of Tris(2-carbamoylmethoxyphenyl)phosphine Oxide. And the article contained the following:

New tripodal ligand, tris(2-carbamoylmethoxyphenyl)phosphine oxide (I), has been synthesized via the alkylation of tris(2-hydroxyphenyl)phosphine oxide with chloroacetamide. The ligand structure has been studied by means of IR and NMR (1H, 31P) spectroscopy as well as X-ray diffraction. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Reference of 2-Chloroacetamide

The Article related to tris carbamoylmethoxyphenyl phosphine mol structure oxide, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Reference of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On April 19, 2017, Ma, Xiaodong; Ge, Yang; Song, Zhendong; Huang, Shanshan; Wang, Changyuan; Zhang, Jianbin; Tang, Zeyao; Liu, Kexin published a patent.Application In Synthesis of N-(3-Aminophenyl)acrylamide The title of the patent was Phosphoryl pyrimidine compound, and its composition and application. And the patent contained the following:

The title phosphoryl pyrimidine compound is shown in formula I, wherein, X is Cl or F; L is -CH2- or -O(CH2)2CH2-; R1 is selected from H, Me, methoxy, and Cl; R2 is selected from methoxy, ethoxy, etc.; R3 is methoxy, ethoxy, etc. The phosphoryl pyrimidine compound is capable of inhibiting Brutons tyrosine kinase, so as to treat tumor diseases, such as Burkitts lymphoma, diffuse large B cell lymphoma, follicular lymphoma, and chronic lymphocytic leukemia. The experimental process involved the reaction of N-(3-Aminophenyl)acrylamide(cas: 16230-24-3).Application In Synthesis of N-(3-Aminophenyl)acrylamide

The Article related to phosphoryl pyrimidine compound preparation antitumor activity, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Application In Synthesis of N-(3-Aminophenyl)acrylamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 15, 2022, Wang, Zheng; Li, Mengxiao; Liao, Yufeng; Pan, Yang; Shuang, Chendong; Li, Jun; Zhou, Qing; Li, Aimin published an article.Reference of 2-Chloroacetamide The title of the article was Formation of disinfection byproducts from chlorinated soluble microbial products: Effect of carbon sources in wastewater denitrification processes. And the article contained the following:

Carbon sources are crucial for biol. denitrification in wastewater treatment that significantly affects the production of soluble microbial products (SMPs), thereby affecting the formation of disinfection byproducts (DBPs) during subsequent chlorination. However, the effect of carbon sources on DBPs formation has not been studied. In this work, sodium acetate, sodium lactate, and glucose were used as carbon sources, and denitrifying SMPs derived from different carbon sources were used as DBPs precursors to investigate the formation potential (FP) of 16 carbonaceous DBPs and 19 nitrogenous DBPs. Results showed that the carbonaceous DBPs FP of SMPs derived from acetate, lactate, and glucose were 502.1-584.3, 250.3-288.9, and 374.7-439.1μg/L, resp., and the nitrogenous DBPs FP were 19.1-45.6, 12.8-21.9, and 7.9-9.0μg/L, resp. After chlorination, the genotoxicity of SMPs measured by the SOS/umu test was also evaluated with 364 ng 4-NQO/L for acetate, 212 ng 4-NQO/L for lactate, and 138 ng 4-NQO/L for glucose. Based on XPS, chem. structures of SMPs were characterized, and their relationship with DBPs FP was investigated to explain the mechanism of DBPs formation. Aromatic C and C-O were found to be the major precursor structures to form carbonaceous DBPs, and their lowest proportions in lactate-derived SMPs caused the lowest carbonaceous DBPs FP. Organic nitrogen, including aromatic N, amide/peptide N, and primary amine N, was the precursor of nitrogenous DBPs. The lowest concentration of dissolved organic nitrogen for glucose-derived SMPs caused the lowest nitrogenous DBPs FP and genotoxicity. Glucose may be a better choice among the three carbon sources in terms of reducing genotoxicity. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Reference of 2-Chloroacetamide

The Article related to carbon disinfection byproduct denitrification wastewater treatment, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Reference of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2022, Pu, Miao; Ailijiang, Nuerla; Mamat, Anwar; Chang, Jiali; Zhang, Qiongfang; Liu, Yifan; Li, Nanxin published an article.Name: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Occurrence of antibiotics in the different biological treatment processes, reclaimed wastewater treatment plants and effluent-irrigated soils. And the article contained the following:

Reclaimed wastewater is increasingly being used for agricultural irrigation to address water scarcity, particularly in arid and semiarid areas. In this study, the occurrence and removal of 24 antibiotics were investigated in two wastewater treatment systems (WWTSs) and their irrigation areas located in the arid northwestern region of China. The different WWTSs included absorption-biodegradation (AB) + anaerobic-anoxic-oxic (AAO) and AAO + AAO + membrane bioreactor (MBR). Nineteen antibiotics were detected, with concentrations ranging from low to 60.8μg/L. The dominant antibiotic classes were quinolones (QNs) and macrolides (MLs) in winter, and MLs and sulfonamides (SAs) in summer. The AAO + AAO + MBR system exhibited better removal efficiencies for most antibiotics, improving their adsorption and biodegradation Except for ofloxacin (OFC) and norfloxacin (NFC), the concentrations of the detected antibiotics were higher in summer than in winter. However, the antibiotic removal efficiency increased by 2-141% in summer compared to winter due to the increase in microbial activity with temperature Even though reclaimed treatment water plants contributed to the removal of antibiotics, residual antibiotics still affected the soil environment after green irrigation. In irrigated soil, QNs were predominantly detected, with a maximum concentration of 150.9 ng/kg for NFC. An ecol. risk assessment showed that OFC, NFC, enrofloxacin, and lomefloxacin presented low or medium ecol. risks in at least two irrigated sites. Thus, more attention should be given to the reuse of reclaimed wastewater, as it may pose toxicity risks to organisms in the soil environment. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotics biol process reclaimed wastewater treatment plant soil, Waste Treatment and Disposal: Biological Treatment Of Aqueous Wastes and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 25, 2019, Zhou, Qilin; Zhang, Fenghua; Xie, Jianhua; Wang, Lixin published a patent.Related Products of 65645-88-7 The title of the patent was Chiral spiro phosphine-amino-oxazoline tridentate ligand, its preparation method and application. And the patent contained the following:

A chiral spiro phosphine-amino-oxazoline tridentate ligand having ruthenium complex exhibits high catalytic activity (TON to 10,000) and enantioselectivity (up to 98% ee) in the asym. hydrogenation of α-ketoamide, which has practical value is provided. The chiral spiro phosphine-amino-oxazoline tridentate ligand comprises a compound of formula I or an enantiomer, racemate, or a catalytically acceptable salt thereof, and having a main structural feature of having a chiral spiroindoline skeleton and having a chiral oxazoline group. The method for preparing a chiral spiro phosphine-amino-oxazoline tridentate ligand by racemic or optically active 7-diaryl/alkylphosphino-7/-aminospiroindole represented by formula 1 having a chiral spiroindoline skeleton used as a starting material. The chiral spiro phosphine-amino-oxazoline tridentate ligand forms a complex with the transition metal salt and can be used to catalyze the asym. catalytic hydrogenation of the carbonyl compound The experimental process involved the reaction of (S)-2-Hydroxy-N-methyl-2-phenylacetamide(cas: 65645-88-7).Related Products of 65645-88-7

The Article related to chiral spiro phosphine amino oxazoline preparation enantioselective hydrogenation catalyst, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Related Products of 65645-88-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 20, 2020, Fernandez-Perez, Hector; Lenartowicz, Pawel; Carreras, Lucas; Grabulosa, Arnald; Kafarski, Pawel; Vidal-Ferran, Anton published an article.Quality Control of 2-Chloroacetamide The title of the article was Access to α-Aminophosphonic Acid Derivatives and Phosphonopeptides by [Rh(P-OP)]-Catalyzed Stereoselective Hydrogenation. And the article contained the following:

The hydrogenation of N-substituted vinylphosphonates using rhodium complexes derived from P-OP ligands L1, ent-L1 or (R,R)-Me-DuPHOS as catalysts has been successfully accomplished, achieving very high levels of stereoselectivity (up to 99% ee or de). The described synthetic strategy allowed for the efficient preparation of alpha-aminophosphonic acid derivatives, e.g. I, and phosphonopeptides, e.g. II, which are valuable building blocks for the preparation of biol. relevant mols. The experimental process involved the reaction of 2-Chloroacetamide(cas: 79-07-2).Quality Control of 2-Chloroacetamide

The Article related to vinyl phosphonate rhodium catalyst hydrogenation mol structure, alpha aminophosphonic acid phophonopeptide asym preparation, Organometallic and Organometalloidal Compounds: Phosphorus Compounds and other aspects.Quality Control of 2-Chloroacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Wang, Juan; Zhang, Peng-Li; Ansari, Mohammad Fawad; Li, Shuo; Zhou, Cheng-He published an article.COA of Formula: C8H10N2O3S The title of the article was Molecular design and preparation of 2-aminothiazole sulfanilamide oximes as membrane active antibacterial agents for drug resistant Acinetobacter baumannii. And the article contained the following:

A series of 2-aminothiazole sulfanilamide oximes were developed as new membrane active antibacterial agents to conquer the microbial infection. Benzoyl derivative 10c was preponderant for the treatment of drug-resistant A. baumannii infection in contrast to norfloxacin and exerted excellent biocompatibility against mammalian cells including erythrocyte and LO2 cell line. Meanwhile, it had ability to eradicate established biofilm to alleviate the resistance burden. Mechanism investigation elucidated that compound 10c was able to disturb the membrane effectively and inhibit lactic dehydrogenase, which led to cytoplasmic content leakage. The cellular redox homeostasis was interfered via the production of reactive oxygen and nitrogen species (RONS), which further contributed to respiratory pathway inactivation and reduction of GSH activity. This work indicated that 2-aminothiazole sulfanilamide oximes could be a promising start for the exploitation of novel antibacterial agents against pathogens. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).COA of Formula: C8H10N2O3S

The Article related to acinetobacter aminothiazole sulfanilamide oxime antibacterial mol design, a. baumannii, aminothiazole, antibacterial, oxime, sulfanilamide, Microbial, Algal, and Fungal Biochemistry: Antimicrobial Sensitivity and other aspects.COA of Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics