Author: Jessica.F

On July 9, 2009, Bappert, Erhard; De Vries, Andreas Hendrikus Maria; Domin, Doris; Helms, Matthias; Imboden, Christoph; Nazir, Zarghun; Skranc, Wolfgang; Spindler, Felix; Stanek, Michael; Tschebull, Wilhelm; Verzijl, Gerardus Karel Maria published a patent.Computed Properties of 65645-88-7 The title of the patent was Process for the preparation of an enantiomeric trisubstituted 3,4-dihydroisoquinoline derivative. And the patent contained the following:

The invention relates to a process for the preparation of the compound of formula I by enantioselective hydrogenation of the corresponding imine intermediate catalyzed by bis[chloro-1,5-cyclooctadiene-iridium] and (S)-1-dicyclohexylphosphino-2-[(S)-α-(dimethylamino)-2-(dicyclohexylphosphino)benzyl]ferrocene. Reaction conditions, such as additives, ratios of substrate/catalyst and solvent systems, play roles respect to enantioselectivity and yields therefore were examined Other metal/chiral ligand catalyst systems were evaluated for the enantioselective hydrogenation of the substrate. The experimental process involved the reaction of (S)-2-Hydroxy-N-methyl-2-phenylacetamide(cas: 65645-88-7).Computed Properties of 65645-88-7

The Article related to dihydroisoquinoline derivative hydrogenation iridium chiral ligand, tetrahydroisoquinoline derivative asym preparation, iridium chiral ligand asym hydrogenation catalyst, Heterocyclic Compounds (One Hetero Atom): Quinolines and Isoquinolines and other aspects.Computed Properties of 65645-88-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 8, 2021, Chen, Yan-Ru; Chung, Hsiao-Wei; Tung, Shih-Huang published an article.Application In Synthesis of N,N-Diethylacetamide The title of the article was On the Formation Mechanism of Nonsolvent-Induced Porous Polylactide Electrospun Fibers. And the article contained the following:

Polylactide (PLA) fibers were electrospun from the solutions of PLA dissolved in the mixtures of its good and poor solvents, and the formation mechanism of the poor solvent-induced porous structure on the fibers was investigated. From a systematic study using the pairs of a variety of good/poor solvents for electrospinning, the conditions, specifically the solvent properties, for producing uniform fibers with controllable pores that appear not only on the surface but also throughout the fibers were proposed. The water miscibility of the good/poor solvents is crucial, which is because the ambient moisture that condenses during electrospinning plays an important role in the formation of the pores. Furthermore, the evaporation rate of the good/poor solvents is another key factor that affects the pore size and pore distribution on fibers because the solvent evaporation rate regulates the moisture condensation and the phase-separated scale that are closely related to fiber morphol. The principles generalized in this work can be applied to other low-polar polymers for controlling the porosity of fibers. In addition, this work demonstrates that the porous PLA fibers can be electrospun from low-toxic solvents and that with a large surface area and storage space provided by the pores, the PLA porous fibers are highly capable of adsorbing oils, with a capacity double that of the smooth counterpart. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Application In Synthesis of N,N-Diethylacetamide

The Article related to porous polylactide electrospun fiber, Textiles and Fibers: Fiber and Yarn Processing and Processing Materials and other aspects.Application In Synthesis of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2015, Suhasini, K. P.; Christopher, V.; Rao, S. Rama Mohana; Kumar, Ch. Praveen; Murthy, Y. L. N. published an article.COA of Formula: C10H11NO3 The title of the article was Synthesis, characterisation and antitubercular screening of 5(4H)-oxazolone derivatives. And the article contained the following:

In search of new antitubercular agents, a new series of 4-(substituted benzylidene)-2-p-tolyloxazol-5(4H)-ones I [R = C6H5, 4-H3CC6H4, 4-CH3OC6H4, 2,5-(CH3O)2C6H3, 2,4,6-(CH3O)3C6H2, 4-ClC6H4, 4-BrC6H4, O2NC6H4] has been designed, synthesized and subjected to evaluate their antitubercular activity for the first time against Mycobacterium tuberculosis H37Rv, in comparison with standard drugs Rifampicin and Isoniazid. The out-put of these studies disclosed that all the synthesized target mols. I of the series displayed good to moderate activity with MIC values ranging 8-64 U+03BCg/mL. Compound I [R = 2,4,6-(CH3O)3C6H2] having three methoxy groups, is the most distinctive compound identified, amongst the series because of its remarkable in vitro antitubercular activity and thus may act as a promising lead mol. for further explorations. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).COA of Formula: C10H11NO3

The Article related to oxazolone preparation antitubercular, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.COA of Formula: C10H11NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 31, 2022, Hyder, M.; O’Donnell, A. D.; Chippindale, A. M.; German, I. M.; Harries, J. L.; Shebanova, O.; Hamley, I. W.; Hayes, W. published an article.Name: 1,3-Diphenylurea The title of the article was Tailoring viscoelastic properties of dynamic supramolecular poly(butadiene)-based elastomers. And the article contained the following:

The discovery and development of new adhesive materials is critical for real-world applications of polymeric composite materials. Herein, we report the design and synthesis of a library of structurally related phase-separated supramol. polyurethanes whose mech. properties and adhesive characteristics can be enhanced through minor structural modifications of the polymer end-group. The interplay between phase separation of the hard domain polar end-groups and soft polybutadiene domains, coupled with tuneable self-assembly afforded by the polar end-groups, gives rise to a class of materials with tuneable mech. properties. Exceptionally strong supramol. adhesives and mech. robust self-healing elastomers were identified. The mech. properties were investigated through tensile testing. Finally, rheol. anal. of the supramol. materials was used to identify suitable healing and adhesive temperatures in addition to elucidate the supramol. polyurethanes’ thermal-responsive nature. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Name: 1,3-Diphenylurea

The Article related to polybutadiene elastomer synthesis phase separation viscoelastic property, Synthetic Elastomers and Natural Rubber: Physical Properties and Testing and other aspects.Name: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 16, 2019, Yan, Dingyuan; Jiang, Heming; Sun, Wenxue; Wei, Wei; Zhao, Jing; Zhang, Xinhao; Wu, Yun-Dong published an article.HPLC of Formula: 685-91-6 The title of the article was Synthesis of Benzofurans and Benzoxazoles through a [3,3]-Sigmatropic Rearrangement: O-NHAc as a Multitasking Functional Group. And the article contained the following:

The synthesis of heterocycles relies heavily on diverse sigmatropic rearrangements triggered by the cleavage of X-Y (X, Y = C, O, N, S, I) bonds. However, a unified rearrangement approach for constructing heterocyclic libraries is highly desirable. Encouraged by computational anal. of [3,3]-sigmatropic rearrangements, we can now rapidly synthesize oxa-heterocycles by treating N-phenoxyacetamides (Ph-ONHAc) with compounds containing an sp-hybridized carbon. The generality of the process is illustrated by the late-stage diversification of natural products, including estrone and an approved drug. A combination of exptl. and computational studies revealed that the reactions proceed through a facile Claisen-like [3,3]-sigmatropic rearrangement/annulation process. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).HPLC of Formula: 685-91-6

The Article related to synthesis benzofuran benzoxazole, sigmatropic rearrangement mol modeling, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.HPLC of Formula: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 3, 2020, Nishiyori, Ryuichi; Okuno, Ken; Shirakawa, Seiji published an article.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the article was Triethylamine Hydroiodide as a Bifunctional Catalyst for the Solvent-Free Synthesis of 2-Oxazolidinones. And the article contained the following:

Among the wide variety of heterocycles, 2-oxazolidinones are recognized as some of the most important heterocyclic compounds in medicinal chem. Therefore, the development of a practical method for their synthesis would be an important development. Herein, we report an efficient method for the synthesis of 2-oxazolidinones under solvent-free conditions using triethylamine hydroiodide as a simple and effective bifunctional organocatalyst. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to epoxide isocyanate triethylamine hydroiodide cyclization catalyst, oxazolidinone preparation, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Safety of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Huang, Wenhua; Dong, Guangping; Mijiti, Zumureti published an article in 2012, the title of the article was One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N’-diisopropylcarbodiimide and Wittig olefination.Quality Control of 2-(4-Methylbenzamido)acetic acid And the article contains the following content:

By a combination of cyclodehydration of N-acyl amino acids with N,N’-diisopropylcarbodiimide (DIC) and non-classical Wittig olefination of the resultant 5(4H)-oxazolones with Ph3P=CHCN and Ph3P=CHCOOEt, 5-oxazoleacetonitriles and 5-oxazoleacetates were synthesized in one-pot in 41-85% and 57-70% yields, resp. E.g., reaction of 4-MeC6H4CONHCH2CO2H with Ph3P:CHCN in presence of DIC gave 85% 5-oxazoleacetonitrile (I). The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Quality Control of 2-(4-Methylbenzamido)acetic acid

The Article related to acyl amino acid cyclodehydration wittig olefination, oxazoleacetonitrile preparation, oxazoleacetate preparation, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Quality Control of 2-(4-Methylbenzamido)acetic acid

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 30, 2015, Suhasini, K. P.; Christopher, V.; Kumar, Ch. Praveen; Rao, S. Rama Mohana; Murthy, Y. L. N. published an article.Safety of 2-(4-Methylbenzamido)acetic acid The title of the article was Synthesis, characterisation and antimycobacterial screening of 5(4H)-oxazolone derivatives against M. tuberculosis H37Rv. And the article contained the following:

A series of 4-(substituted benzylidene)-2-p-tolyloxazol-5(4H)-ones I [R = H, 4-Cl, 2,5-(OCH3)2, etc.] has been designed, synthesized and subjected to evaluate their antimycobacterial activity against Mycobacterium tuberculosis H37Rv in comparison with standard drugs Rifampicin and Isoniazid. The out-put of these studies disclosed that all the synthesized target mols. of the series displayed good to moderate activity with MIC values ranging 8-64 U+03BCg/mL. The compound I [R = 2,4,6-(OCH3)3] is the most distinctive compound identified, amongst the series because of its remarkable in vitro antimycobacterial activity and thus may act as a promising lead mol. for further explorations. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Safety of 2-(4-Methylbenzamido)acetic acid

The Article related to oxazolone preparation antimycobacterial, methylbenzamido acetic acid preparation aldehyde aryl erlenmeyer plochl azlactone, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Safety of 2-(4-Methylbenzamido)acetic acid

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 7, 2022, Rostami, Ali; Ebrahimi, Amirhossein; Sakhaee, Nader; Golmohammadi, Farhad; Al-Harrasi, Ahmed published an article.Computed Properties of 102-07-8 The title of the article was Microwave-Assisted Electrostatically Enhanced Phenol-Catalyzed Synthesis of Oxazolidinones. And the article contained the following:

An electrostatically enhanced phenol is utilized as a straightforward, sustainable, and potent one-component organocatalyst for the atom-economic transformation of epoxides to oxazolidinones under microwave irradiation Integrating a pos. charged center into phenols over a modular one-step preparation gives rise to a bifunctional system with improved acidity and activity, competent in rapid assembly of epoxides and isocyanates under microwave irradiation in a short reaction time (20-60 min). A careful assessment of the efficacy of various pos. charged phenols and anilines and the impact of several factors, such as catalyst loading, temperature, and the kind of nucleophile, on catalytic reactivity were examined Under neat conditions, this one-component catalytic platform was exploited to prepare more than 40 examples of oxazolidinones from a variety of aryl- and alkyl-substituted epoxides and isocyanates within minutes, where up to 96% yield and high degree of selectivity were attained. DFT calculations to achieve reaction barriers for different catalytic routes were conducted to provide mechanistic understanding and corroborated the exptl. findings in which concurrent epoxide ring-opening and isocyanate incorporation were proposed. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Computed Properties of 102-07-8

The Article related to oxazolidinone preparation microwave irradiation, epoxide isocyanate cycloaddition electrostatically enhanced phenol catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Computed Properties of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 7, 2022, Rostami, Ali; Ebrahimi, Amirhossein; Sakhaee, Nader; Golmohammadi, Farhad; Al-Harrasi, Ahmed published an article.Reference of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the article was Microwave-Assisted Electrostatically Enhanced Phenol-Catalyzed Synthesis of Oxazolidinones. And the article contained the following:

An electrostatically enhanced phenol is utilized as a straightforward, sustainable, and potent one-component organocatalyst for the atom-economic transformation of epoxides to oxazolidinones under microwave irradiation Integrating a pos. charged center into phenols over a modular one-step preparation gives rise to a bifunctional system with improved acidity and activity, competent in rapid assembly of epoxides and isocyanates under microwave irradiation in a short reaction time (20-60 min). A careful assessment of the efficacy of various pos. charged phenols and anilines and the impact of several factors, such as catalyst loading, temperature, and the kind of nucleophile, on catalytic reactivity were examined Under neat conditions, this one-component catalytic platform was exploited to prepare more than 40 examples of oxazolidinones from a variety of aryl- and alkyl-substituted epoxides and isocyanates within minutes, where up to 96% yield and high degree of selectivity were attained. DFT calculations to achieve reaction barriers for different catalytic routes were conducted to provide mechanistic understanding and corroborated the exptl. findings in which concurrent epoxide ring-opening and isocyanate incorporation were proposed. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Reference of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to oxazolidinone preparation microwave irradiation, epoxide isocyanate cycloaddition electrostatically enhanced phenol catalyst, Heterocyclic Compounds (More Than One Hetero Atom): Oxazoles, Isoxazoles and other aspects.Reference of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics