Author: Jessica.F

On February 2, 2021, Tang, Jinpeng; Fang, Ji; Tam, Nora Fungyee; Yang, Yang; Dai, Yunv; Zhang, Jinhua; Shi, Yuming published an article.Category: amides-buliding-blocks The title of the article was Impact of phytoplankton blooms on concentrations of antibiotics in sediment and snails in a subtropical river, China. And the article contained the following:

The present three-year field investigation on sediment in the eutrophic Pearl River in South China showed that concentrations of sulfonamides (SAs), fluoroquinolones (FQs), and macrolides (MLs) in the river areas where blooms occurred were 4.6, 2.4, and 3.4 times higher than those without blooms, resp., but the resp. concentrations of tetracycline (TC) and oxytetracycline (OTC) in the areas with blooms were 2.6 and 3.8 times lower than those without. Significant pos. correlations were found between concentrations of chlorophyll a in water and most antibiotics in sediment. Further investigation in each season suggested that lower diffusion but higher sinking were possible reasons driving the burial of sulfapyridine (SPD), sulfamethoxazole (SMX), and trimethoprim (TMP) in sediment from areas where blooms occurred, with burial rates up to 14.86, 48.58, and 52.19 g month-1, resp. Concentrations of TCs in both water and sediment were inversely correlated with phytoplankton biomass, which might be related to the enhanced biodegradation capacity of bacteria caused by phytoplankton blooms. Phytoplankton also affected concentrations of antibiotics in the snail, Bellamya purificata, with higher values in March but lower values in Sept. The concentration of antibiotics in snails pos. correlated with that in sediment when snails were dormant but with antibiotics in water after dormancy. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Category: amides-buliding-blocks

The Article related to phytoplankton blooms concentration antibiotics sediment snails subtropical river china, antibiotics, biodegradable pollutants, chemodynamics, eutrophic river, sedimentation and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 30, 2020, Wang, Dong; Fu, Zhifei; Xing, Yanchao; Tan, Yao; Han, Lifeng; Yu, Haiyang; Wang, Tao published an article.Synthetic Route of 27115-50-0 The title of the article was Rapid identification of chemical composition and metabolites of Pingxiao Capsule in vivo using molecular networking and untargeted data-dependent tandem mass spectrometry. And the article contained the following:

Pingxiao capsule (PXC) is a herbal medicine used for adjuvant therapy in breast cancer. However, the constituents and absorbed components of the formula and their related metabolites have not been elucidated to date. PXC is a typical traditional Chinese medicine formula consisting of Strychnos nux-vomica L., Curcuma wenyujin Y. H., Agrimonia pilosa Ledeb., Toxicodendron vernicifluum, Trogopterus dung, alumen, potassium nitrate (saltpeter) and Citrus aurantium L. In this study, a ultra-high performance liquid chromatog. system equipped with high resolution Q-Orbitrap mass spectrometry (MS) and comparative Global Natural Product Social mol. networking together with the Compound Discoverer software were used to identify metabolites of PXC in vitro and in vivo. Based on untargeted data-dependent MS2 and data-mining techniques, 89 peaks of alkaloids, flavonoids, organic acid and phenolic compounds were identified in a PXC 70% methanol extract Furthermore, 15 absorbed prototype compounds and their metabolites were rapidly confirmed in rat blood. Glucuronidation, oxidation, methylation and hydroxylation were the main metabolic pathways. We fully clarified the chem. constituents of PXC and provided a scientific and efficient strategy for rapid discovery and identification of prototypes and their metabolites in rat plasma using high-resolution MS aided by Global Natural Product Social and Compound Discoverer software. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).Synthetic Route of 27115-50-0

The Article related to pingxiao capsule chem composition metabolite mol networking mass spectrometry, pingxiao capsule, chemical constituents, mass spectrometry, metabolites, molecular networking and other aspects.Synthetic Route of 27115-50-0

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 1, 2022, Xing, Liqun; Li, Aimin; Sun, Jie; Kong, Fanjie; Kong, Ming; Li, Jun; Zhang, Rui published an article.Electric Literature of 144-80-9 The title of the article was Insights into the occurrence, elimination efficiency and ecological risk of antibiotics in rural domestic wastewater treatment facilities along the Yangtze River Basin, China. And the article contained the following:

China is embarking on the treatment of rural domestic wastewater, but little information on the characteristics of antibiotics in the rural domestic wastewater is available. As one of the most important new-emerging pollutants, antibiotic has been explicitly proposed to be controlled and treated since the fifth plenary session of the 19th Central Committee of the Communist Party of China. Thus, the occurrence, elimination efficiency and ecol. risk of antibiotics, as well as conventional wastewater quality parameters were investigated in influents and effluents from 41 rural domestic wastewater treatment facilities (RD-WWTFs) along the Yangtze River Basin. Results showed that elimination efficiencies of routinely monitored conventional pollutants in 33 RD-WWTFs (accounting for 80.5%) were effective based on conventional wastewater quality parameters. Of 39 target antibiotics selected, 26 ones were detected in the influents and effluents with a detection frequency (DF) between 2.4% and 100%. No significant decrease of antibiotics was observed in the effluents compared with that in the influents except chlortetracyclin (CTE) and tetracycline (TCs). The composition characteristics of antibiotics showed regional differences. Among the investigated antibiotics, ofloxacin (OFX), doxycycline (DOX), roxithromycin (ROX) and lincomycin (LIN) were the predominant, totally accounted for a median percentage of more than 60% of ΣAB concentrations in both influents and effluents. Ecol. risk values of ΣABs showed that 11 effluents presented high risks (26.8%), 18 ones had moderate risks (43.9%), and the rest 12 ones showed low risks (29.3%). Moreover, oxytetracycline (OXY), norfloxacin (NOR), LIN and ROX was the dominant contributors to the ecol. risk values. Overall, the elimination effect of antibiotics was limited in RD-WWTFs along the Yangtze River Basin, which was likely to pose potential adverse impacts on aquatic ecosystems. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Electric Literature of 144-80-9

The Article related to antibiotics ecol risk domestic wastewater treatment china, emerging organic pollutants, environmental impact, influent and effluent, regional differences, removal efficiency and other aspects.Electric Literature of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On June 15, 2021, A, Dan; Chen, Chun-xing; Zou, Meng-yao; Deng, Yang-yang; Zhang, Xiao-meng; Du, Jian-jun; Yang, Yang published an article.Name: N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Removal efficiency, kinetic, and behavior of antibiotics from sewage treatment plant effluent in a hybrid constructed wetland and a layered biological filter. And the article contained the following:

Sewage treatment plant (STP) is the major point source of antibiotic contamination, yet the advanced treatment of antibiotic polluted STP effluent has not been given necessary attention. This study is conducted to evaluate the removal efficiency, kinetic, and behavior of sulfonamides, quinolones, tetracyclines, and macrolides antibiotics from STP effluent in a hybrid constructed wetland (HCW) and a layered biol. filter (LBF) at different hydraulic loading rates (HLRs). The results showed that the removal efficiency of antibiotics in all the HLRs was ranked as follow: quinolones of HCW (70-95%) > macrolides of HCW (58-77%) > tetracyclines of both systems (59-67%) > quinolones of LBF (28-64%) > macrolides of LBF (13-25%) > sulfonamides of both systems (<0%). The optimal HLR is 1.0 m/day for quinolones and 2.0 m/day for tetracyclines-macrolides in the HCW, and 6.4 m/day for quinolones-tetracyclines in the LBF, resp. Although HCW performed better on the removal of most antibiotics, LBF exhibited stronger total loading toleration and higher removal loading ability to antibiotics. Among them, quinolones were markedly removed by multiple effect of substrate adsorption, microbial anaerobic degradation, and photolysis in the HCW (planted), and by filter sorption and interception in the LBF (unplanted); adsorption is the dominant elimination approach for tetracyclines in both systems; plant uptake plays a significant role on the removal of macrolides in the HCW. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotic removal kinetics hcw lbf wastewater sewage treatment plant, artificial wetland, biofilter, deep purification, pharmaceutical, wastewater treatment plant discharge and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xue, Weifeng; Yang, Chunguang; Liu, Mengyao; Lin, Xiaomei; Wang, Mei; Wang, Xiaowen published an article in 2022, the title of the article was Metabolomics Approach on Non-Targeted Screening of 50 PPCPs in Lettuce and Maize.Name: N-((4-Aminophenyl)sulfonyl)acetamide And the article contains the following content:

The metabolomics approach has proved to be promising in achieving non-targeted screening for those unknown and unexpected (U&U) contaminants in foods, but data anal. is often the bottleneck of the approach. In this study, a novel metabolomics anal. method via seeking marker compounds in 50 pharmaceutical and personal care products (PPCPs) as U&U contaminants spiked into lettuce and maize matrixes was developed, based on ultrahigh-performance liquid chromatog.-tandem mass spectrometer (UHPLC-MS/MS) output results. Three concentration groups (20, 50 and 100 ng mL-1) to simulate the control and exptl. groups applied in the traditional metabolomics anal. were designed to discover marker compounds, for which multivariate and univariate anal. were adopted. In multivariate anal., each concentration group showed obvious separation from other two groups in principal component anal. (PCA) and orthogonal partial least squares discriminant anal. (OPLS-DA) plots, providing the possibility to discern marker compounds among groups. Parameters including S-plot, permutation test and variable importance in projection (VIP) in OPLS-DA were used for screening and identification of marker compounds, which further underwent pairwise t-test and fold change judgement for univariate anal. The results indicate that marker compounds on behalf of 50 PPCPs were all discovered in two plant matrixes, proving the excellent practicability of the metabolomics approach on non-targeted screening of various U&U PPCPs in plant-derived foods. The limits of detection (LODs) for 50 PPCPs were calculated to be 0.4∼2.0μg kg-1 and 0.3∼2.1μg kg-1 in lettuce and maize matrixes, resp. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Name: N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to lettuce maize ppcps nontargeted screening metabolomics, marker compounds, metabolomics, non-targeted screening, pharmaceutical and personal care products, plant-derived food and other aspects.Name: N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Elliott, Rory; Ryan, Aoife A.; Aggarwal, Aviral; Zhu, Nianyong; Steuber, Friedrich W.; Senge, Mathias O.; Schmitt, Wolfgang published an article in 2021, the title of the article was 2D porphyrinic metal-organic frameworks featuring rod-shaped secondary building units.Application In Synthesis of N,N-Diethylacetamide And the article contains the following content:

Metal-organic frameworks (MOFs) encompass a rapidly expanding class of materials with diverse potential applications including gas storage, mol. separation, sensing and catalysis. So-called ‘rod MOFs’, which comprise infinitely extended 1D secondary building units (SBUs), represent an underexplored subclass of MOF. Further, porphyrins are considered privileged ligands for MOF synthesis due to their tunable redox and photophys. properties. In this study, the CuII complex of 5,15-bis(4-carboxyphenyl)-10,20-diphenylporphyrin (H2L-CuII, where H2 refers to the ligand’s carboxyl H atoms) is used to prepare two new 2D porphyrinic rod MOFs PROD-1 and PROD-2. Single-crystal X-ray anal. reveals that these frameworks feature 1D MnII- or CoII-based rod-like SBUs that are coordinated by labile solvent mols. and photoactive porphyrin moieties. Both materials were characterised using IR (IR) spectroscopy, powder X-ray diffraction (PXRD) spectroscopy and thermogravimetric anal. (TGA). The structural attributes of PROD-1 and PROD-2 render them promising materials for future photocatalytic investigations. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Application In Synthesis of N,N-Diethylacetamide

The Article related to porphyrinic metal organic framework secondary building unit, 2d mof, 2d materials, mof, porphyrin mof, porphyrinoids, coordination chemistry, metal-organic framework, rod mof and other aspects.Application In Synthesis of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2022, Rambaldo, Lorenzo; Avila, Hector; Escola Casas, Monica; Guivernau, Miriam; Vinas, Marc; Trobajo, Rosa; Perez-Burillo, Javier; Mann, David G.; Fernandez, Belen; Biel, Carme; Rizzo, Luigi; Bayona, Josep M.; Matamoros, Victor published an article.Computed Properties of 144-80-9 The title of the article was Assessment of a novel microalgae-cork based technology for removing antibiotics, pesticides and nitrates from groundwater. And the article contained the following:

Groundwater pollution has increased in recent years due to the intensification of agricultural and livestock activities. This results in a significant reduction in available freshwater resources. Here, we have studied the long term assessment of a green technol. (1-4 L/day) based on a photobioreactor (PBR) containing immobilized microalgae-bacteria in polyurethane foam (PF) followed by a cork filter (CF) for removing nitrates, pesticides (atrazine and bromacil), and antibiotics (sulfamethoxazole and sulfacetamide) from groundwater. The prototype was moderately effective for removing nitrates (58%) at an HRT of 8 days, while its efficiency decreased at a HRT of 4 and 2 days (<20% removal). The combined use of PBR-CF enabled antibiotics and pesticides to be attenuated by up to 95% at an HRT of 8 days, but their attenuation decreased with shorter HRT, with pesticides being the compounds most affected (reducing from 97 to 98% at an HRT of 8 days to 23-45% at an HRT of 2 days). Pesticide transformation products were identified after the CF, supporting biodegradation as the main attenuation process. A gene-based metataxonomic assessment linked the attenuation of micropollutants to the presence of specific pesticide biodegradation species (e.g. genus Phenylobacterium, Sphingomonadaceae, and Caulobacteraceae). Therefore, the results highlighted the potential use of microalgae and cork to treat polluted groundwater. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Computed Properties of 144-80-9

The Article related to groundwater pesticide nitrate antibiotics microalgae cork transformation product, antibiotics, microalgae, nitrates, pesticides, photo-biodegradation, transformation products and other aspects.Computed Properties of 144-80-9

Referemce:
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Amide – an overview | ScienceDirect Topics

On February 15, 2022, Riggs, Daniel W.; Malovichko, Marina V.; Gao, Hong; McGraw, Katlyn E.; Taylor, Breandon S.; Krivokhizhina, Tatiana; Rai, Shesh N.; Keith, Rachel J.; Bhatnagar, Aruni; Srivastava, Sanjay published an article.HPLC of Formula: 27115-50-0 The title of the article was Environmental exposure to volatile organic compounds is associated with endothelial injury. And the article contained the following:

Volatile organic compounds (VOCs) are airborne toxicants abundant in outdoor and indoor air. High levels of VOCs are also present at various Superfund and other hazardous waste sites; however, little is known about the cardiovascular effects of VOCs. We hypothesized that ambient exposure to VOCs exacerbate cardiovascular disease (CVD) risk by depleting circulating angiogenic cells (CACs). In this cross-sectional study, we recruited 603 participants with low-to-high CVD risk and measured 15 subpopulations of CACs by flow cytometry and 16 urinary metabolites of 12 VOCs by LC/MS/MS. Associations between CAC and VOC metabolite levels were examined using generalized linear models in the total sample, and sep. in non-smokers. In single pollutant models, metabolites of ethylbenzene/styrene and xylene, were neg. associated with CAC levels in both the total sample, and in non-smokers. The metabolite of acrylonitrile was neg. associated with CD45dim/CD146+/CD34+/AC133+ cells and CD45+/CD146+/AC133+, and the toluene metabolite with AC133+ cells. In anal. of non-smokers (n = 375), multipollutant models showed a neg. association with metabolites of ethylbenzene/styrene, benzene, and xylene with CD45dim/CD146+/CD34+ cells, independent of other VOC metabolite levels. Cumulative VOC risk score showed a strong neg. association with CD45dim/CD146+/CD34+ cells, suggesting that total VOC exposure has a cumulative effect on pro-angiogenic cells. We found a non-linear relationship for benzene, which showed an increase in CAC levels at low, but depletion at higher levels of exposure. Sex and race, hypertension, and diabetes significantly modified VOC associated CAC depletion. Low-level ambient exposure to VOCs is associated with CAC depletion, which could compromise endothelial repair and angiogenesis, and exacerbate CVD risk. The experimental process involved the reaction of 2-(4-Methylbenzamido)acetic acid(cas: 27115-50-0).HPLC of Formula: 27115-50-0

The Article related to volatile organic compound environmental exposure endothelial injury, benzene, circulating angiogenic cells, endothelial injury, ethylbenzene, vocs, volatile organic compounds and other aspects.HPLC of Formula: 27115-50-0

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Guo, Feng; Wang, Yanan; Peng, Jie; Huang, Hetian; Tu, Xiangting; Zhao, Hu; Zhan, Nan; Rao, Zhu; Zhao, Gaofeng; Yang, Hongbo published an article in 2022, the title of the article was Occurrence, Distribution, and Risk Assessment of Antibiotics in the Aquatic Environment of the Karst Plateau Wetland of Yangtze River Basin, Southwestern China.Recommanded Product: 144-80-9 And the article contains the following content:

In this study, the occurrence, distribution, and ecol. risk of 40 commonly used antibiotics, including 15 sulfonamides (SAs), 9 fluoroquinolones (FQs), 7 macrolides (MCs), 3 tetracyclines (TCs), 2 chloramphenicols (CAPs), and 4 other categories, in the aquatic environment of the karst plateau wetland Caohai of the Yangtze River basin in southwestern China are reported. In total, 27 antibiotics were detected, with the detection rate ranging from 5% to 100%. The total concentration at each site ranged from 21.8 ng/L to 954 ng/L, with the average concentration being 189 ng/L. FQs and MCs were the most predominant categories, contributing 29.3% and 25.0% of the total antibiotic burden. The five most commonly detected antibiotics were ciprofloxacin (CIP), oxytetracycline (OTC), acetyl sulfamethoxazole (ASMZ), norfloxacin (NOR), and florfenicol (FF). The spatial distribution of the total concentration at each site demonstrated a decreasing trend from the southeastern area upstream adjoining the main counties to the northwestern area downstream, indicating that human activities have a great impact. Meanwhile, the natural attenuation rates of different types of antibiotics in the direction of flow ranged from 17.6% to 100%, which implied the natural purification potential of the wetland for antibiotics. The cluster anal. results indicated that domestic sewage and wastewater from agriculture and animal husbandry were the main sources of contamination in the surrounding wetland. Risk quotients (RQs) assessment showed that most of the individuals were at low to medium risk and that the adverse risks posed by mixtures of antibiotics were higher than those posed by the individual antibiotics. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Recommanded Product: 144-80-9

The Article related to antibiotic aquatic environment plateau wetland risk assessment southwestern china, antibiotics, aquatic environment, distribution, occurrence, plateau wetland, risk assessment and other aspects.Recommanded Product: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On March 9, 2022, He, Tong; Cui, Peng Lei; Liu, Jing; Feng, Cheng; Wang, Jian Ping published an article.HPLC of Formula: 144-80-9 The title of the article was Production of a Natural Dihydropteroate Synthase and Development of a Signal-Amplified Pseudo-Immunoassay for the Determination of Sulfonamides in Pork. And the article contained the following:

In this study, a type of magnetic photoaffinity-labeled activity-based protein profiling probe for sulfonamide drugs was first synthesized for the purpose of capturing the natural dihydropteroate synthase of Escherichia coli by using simple incubation and magnetic separation After characterization of its identity with LC-ESI-MS/MS, this enzyme was used as a recognition reagent to develop a direct competitive pseudo-ELISA for the determination of the residues of 40 sulfonamides in pork. Because of the use of streptavidin-horseradish peroxidase and biotinylated horseradish peroxidase as a signal-amplified system, the limits of detection for the 40 drugs were in the range of 0.001-0.016 ng/mL. Compared to the steps in a conventional assay formation, the operation steps were the same, but the sensitivities increased 32-88-fold. Furthermore, the assay performances were better than the previously reported immunoassays performances for sulfonamides. Therefore, this method could be used as a practical tool for multiscreening the trace levels of sulfonamides residues in food samples. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).HPLC of Formula: 144-80-9

The Article related to dihydropteroate synthase pseudo immunoassay sulfonamide pork, dihydropteroate synthase, magnetic photoaffinity-labeled probe, pork, signal-amplified pseudo-elisa, sulfonamides and other aspects.HPLC of Formula: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics