Category: 123-39-7

Kamysbayev, Vladislav published the artcileCovalent surface modifications and superconductivity of two-dimensional metal carbide MXenes, Recommanded Product: N-Methylformamide, the main research area is titanium carbide MXene surface termination electronic property superconductivity.

Versatile chem. transformations of surface functional groups in two-dimensional transition-metal carbides (MXenes) open up a previously unexplored design space for this broad class of functional materials. We introduce a general strategy to install and remove surface groups by performing substitution and elimination reactions in molten inorganic salts. Successful synthesis of MXenes with oxygen, imido, sulfur, chlorine, selenium, bromine, and tellurium surface terminations, as well as bare MXenes (no surface termination), was demonstrated. These MXenes show distinctive structural and electronic properties. For example, the surface groups control interat. distances in the MXene lattice, and Tin+1Cn (n = 1, 2) MXenes terminated with telluride (Te2-) ligands show a giant (>18%) in-plane lattice expansion compared with the unstrained titanium carbide lattice. The surface groups also control superconductivity of niobium carbide MXenes.

Science (Washington, DC, United States) published new progress about Density of states. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Smirnov, Valeriy I. published the artcileThermochemical investigation of glycyl-L-alanine dissolution in aqueous solution of some acetamides and formamides at T = 298.15 K (Similarities and differences), Recommanded Product: N-Methylformamide, the main research area is acetamide formamide glycyl alanine dissolution.

The paper presents data on the glycyl-L-alanine dissolution enthalpies in aqueous solutions of formamide (FA), N-methyl-formamide (MFA), N,N-dimethylformamide (DMF), acetamide (AM), N-methyl-acetamide (NMA), and N,N-dimethylacetamide (DMA) at an organic co-solvent concentration x2 = 0 ÷ 0.25 – mole fraction and T = 298.15 K, obtained by calorimetry. The standard values of dissolution enthalpies (ΔsolHo), transfer enthalpies (ΔtrHo), and enthalpic coefficients of pairwise interaction (hxy) were calculated from these data. The dependences of the enthalpic characteristics of glycyl-L-alanine dissolution on the mixture composition and the interaction energy between the mixture components have been established. A comparative anal. of the values of the enthalpic coefficients of pairwise interactions of glycyl-L-alanine, glycyl-glycine, and glycyl-L-tyrosine in similarly mixed solvents has been carried out. A quant. assessment of the enthalpy contributions of the side-chains of glycyl-L-alanine and glycyl-L-tyrosine to the energetics of interaction with amide mols. in an aqueous solution is given.

Journal of Chemical Thermodynamics published new progress about Solution enthalpy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Orlov, Alexey A. published the artcileChemoinformatics-Driven Design of New Physical Solvents for Selective CO2 Absorption, Application In Synthesis of 123-39-7, the main research area is chemoinformatic driven design phys solvent CO2 absorption; carbon dioxide; carbon monoxide; chemoinformatics; gas solubility; hydrogen; industrial gases; machine learning; methane; nitrogen.

The removal of CO2 from gases is an important industrial process in the transition to a low-carbon economy. The use of selective phys. (co-)solvents is especially perspective in cases when the amount of CO2 is large as it enables one to lower the energy requirements for solvent regeneration. However, only a few phys. solvents have found industrial application and the design of new ones can pave the way to more efficient gas treatment techniques. Exptl. screening of gas solubility is a labor-intensive process, and solubility modeling is a viable strategy to reduce the number of solvents subject to exptl. measurements. In this paper, a chemoinformatics-based modeling workflow was applied to build a predictive model for the solubility of CO2 and four other industrially important gases (CO, CH4, H2, and N2). A dataset containing solubilities of gases in 280 solvents was collected from literature sources and supplemented with the new data for six solvents measured in the present study. A modeling workflow based on the usage of several state-of-the-art machine learning algorithms was applied to establish quant. structure-solubility relationships. The best models were used to perform virtual screening of the industrially produced chems. It enabled the identification of compounds with high predicted CO2 solubility and selectivity toward other gases. The prediction for one of the compounds, 4-methylmorpholine, was confirmed exptl.

Environmental Science & Technology published new progress about Air purification. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Application In Synthesis of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Gao, Feng published the artcileDesign, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin, Formula: C2H5NO, the main research area is imidazopyridine derivative preparation antitumor activity tubulin katanin; Antitumor; Imidazo[4,5-c]pyridin-2-one; Katanin; Tubulin polymerization.

Microtubule is one of the important targets for cancer treatment. A novel class of diaryl substituted imidazo[4,5-c]pyridin-2-ones and imidazo[4,5-c]pyridines were designed based on combination principles by merging the structures of β-lactams and purine-type compounds known as tubulin polymerization inhibitor and katanin activity up-regulator, resp. Their antitumor activities were evaluated in vitro and the mechanism was elucidated, leading to the identification of 1,6-diaryl-1H-imidazo[4,5-c]pyridin-2(3H)-one I as the first bifunctional agent that can target both tubulin and katanin simultaneously. The in vivo assays verified that compound I significantly inhibited xenograft tumor growth with good pharmacokinetic characteristics, demonstrating a promising potential for further development into anti-tumor drug candidates with a unique mechanism of dual-targeting microtubule.

European Journal of Medicinal Chemistry published new progress about Antitumor agents. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Shankaraiah, P. published the artcileSynthesis and Cytotoxicity of Quinazolin-4(3H)-one Based Peptides, Category: amides-buliding-blocks, the main research area is isocyanide benzaldehyde benzoic acid Ugi multicomponent reaction; quinazolinone preparation antitumor.

A series of quinazolin-4(3H)-one derivatives was synthesized in high yields using the multicomponent Ugi reaction and characterized by IR, NMR and mass spectral data. The products has been tested for their cytotoxic activity against HeLa cells. Two tested compounds had shown potent activity compared to standard drug Doxorubicin. The in silico docking studies of the compounds against quinone reductase-2 (4ZVM) enzyme had also supported their activity.

Russian Journal of General Chemistry published new progress about Antitumor agents. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Category: amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Owen, Aniekan Ekpenyong published the artcileManganese-Catalyzed Dehydrogenative Synthesis of Urea Derivatives and Polyureas, Related Products of amides-buliding-blocks, the main research area is amine methanol manganese catalyst dehydrogenative coupling reaction; formamide amine manganese catalyst dehydrogenative coupling reaction; urea preparation.

Here the synthesis of (poly)ureas using much less toxic reagents-(di)amines and methanol-via a catalytic dehydrogenative coupling process. The reaction was catalyzed by a pincer complex of an earth-abundant metal, manganese, and liberates H2 gas, valuable by itself, as the only byproduct, making the overall process highly atom-economic. A broad variety of sym. and unsym. urea derivatives and polyureas was synthesized in moderate to quant. yields using this catalytic protocol. Mechanistic insights was also been provided using experiments and DFT computation, suggesting that the reaction proceeds via an isocyanate intermediate.

ACS Catalysis published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Vivek, J. Padmanabhan published the artcileNegating the Interfacial Resistance between Solid and Liquid Electrolytes for Next-Generation Lithium Batteries, Formula: C2H5NO, the main research area is negate interfacial resistance solid liquid electrolyte lithium battery water; electrolyte additives; lithium metal batteries; lithium−ion transport; solid−liquid electrolyte interphases; solid−liquid hybrid electrolytes.

The combination of solid and liquid electrolytes enables the development of safe and high-energy batteries where the solid electrolyte acts as a protective barrier for a high-energy lithium metal anode, while the liquid electrolyte maintains facile electrochem. reactions with the cathode. However, the contact region between the solid and liquid electrolytes is associated with a very high resistance, which severely limits the specific energy that can be practically delivered. In this work, we demonstrate a suitable approach to virtually suppress such interfacial resistance. Using a NASICON-type solid electrolyte in a variety of liquid electrolytes (ethers, DMSO, acetonitrile, ionic liquids, etc.), we show that the addition of water as electrolyte additive decreases the interfacial resistance from >100 Ω cm2 to a negligible value (<5 Ω cm2). XPS measurements reveal that the composition of the solid-liquid electrolyte interphase is very similar in wet and dry liquid electrolytes, and thus the suppression of the associated resistance is tentatively ascribed to a plasticizer or preferential ion solvation effect of water, or to a change in the interphase morphol. or porosity caused by water. Our simple estimates show that the improvement in the solid-liquid electrolyte interphase resistance observed here could translate to an enhancement of 15-22% in the practical energy d. of a Li-S or Li-O2 battery and improvements in the roundtrip efficiency of 21-28 percentage points. ACS Applied Materials & Interfaces published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Volli, Vikranth published the artcileOxidative stability, thermal hazard analysis, and decomposition kinetics of 1-methylimidazolium nitrate via DSC, TGA, and GC/MS, Safety of N-Methylformamide, the main research area is methylimidazolium nitrate oxidative stability thermal hazard analysis decomposition kinetics.

Imidazolium-based ionic liquids are green solvents used as separation and electrolyte media in liquid-liquid extraction processes and electrochem. devices. However, they are volatile and flammable once they reach their thermal decomposition temperatures In the present study, the oxidative stability, decomposition, and combustion reaction of 1-methylimidazolium nitrate [Mim][NO3] were investigated via thermogravimetric anal. (TG) and differential scanning calorimetry (DSC). TG anal. revealed a single-stage mass loss between 117.6 and 230.2 °C with oxidative onset temperatures in the range of 126.6-163.2 °C with the increase in heating rate (1.0, 2.0, 4.0, and 8.0 °C min-1). DSC results indicated the degradation as exothermic with the average enthalpy of decomposition as 1610.4 J g-1. The estimated average value of apparent activation energy using isoconversional methods such as Kissinger, FWO, and Friedman was in the range of 106.1-114.2 kJ mol-1, and the reaction function (autocatalytic model) is expressed as: f(α) = (1 – α)1.42 (0.017 + α0.62) using multivariate nonlinear regression. The GC/MS anal. revealed the formation of methane isocyanate indicating the hazardous, toxic, corrosive, and carcinogenic nature of the decomposed gases. This research was aimed to develop a predictive model for oxidative degradation behavior and to provide the necessary basis for the design of precise safety systems.

Journal of Thermal Analysis and Calorimetry published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Safety of N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Andreou, Fevronia T. published the artcileIntercalation of N-methylformamide in kaolinite: In situ monitoring by near-infrared spectroscopy and X-ray diffraction, HPLC of Formula: 123-39-7, the main research area is methylformamide kaolinite IR spectroscopy Xray diffraction.

The selective self-assembly of small mols. in the interlayer of kaolinite is a fundamentally important and technol. relevant process, typically studied ex situ by X-ray diffraction (XRD). Near-IR (NIR) spectroscopy is now introduced to provide a complementary local structural description of intercalation with improved control of exptl. conditions. New NIR- and XRD-based proxies were developed and applied to the real-time monitoring of N-methylformamide (NMF) intercalation in two reference kaolinites differing in stacking order. The commonly employed XRD-based formalism was found to overestimate reaction progress. The bonding of NMF in the interlayer was independent of reaction progress and kaolinite type. Both NIR and XRD recorded identical sigmoidal kinetics. Isothermal NIR monitoring (25-80°C) yielded time-temperature superimposable sigmoidals with an apparent activation energy of ∼60 kJ/mol, common to both samples. All NIR and XRD data series could be described as linear combinations of empty and fully intercalated kaolinite. The filling of the interlayer was too fast to be observed The sigmoidal curves were instead modeled as the log-normally distributed response of an ensemble of intercalating entities, presumably crystallites. The multiplicative standard deviation of the distribution, which determines its steepness, is a sample-specific, temperature-independent property of kaolinite.

Applied Clay Science published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, HPLC of Formula: 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ma, Jing published the artcileProton transfer reaction of the formamide and its derivatives characterized via the Kohn-Sham potential, HPLC of Formula: 123-39-7, the main research area is formamide derivative proton transfer reaction Kohn Sham potential.

Proton transfer (PT) reaction plays a critical role in chem. and biol. processes, but the bond breaking and forming during the reaction as well as the charge change are rarely concerned. In this work, Kohn-Sham potential (KSpot) quantum chem. topol. (QCT) method is used to partition a mol. into resp. basins and yield a new at. charge model. The bond critical point and Dpb gained from KSpot are applied to determine chem. bond forming and estimate the bond strength, resp. Moreover, KSpot mol. face has been defined by the KSpot that presents the reactive site of formamide during PT process. In general, KSpot method can present the charge change, visualize reactive sites and quantify the chem. bond strength in the PT process, which can be considered as the cornerstone for other chem. reactions.

Computational & Theoretical Chemistry published new progress about Activation energy. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, HPLC of Formula: 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics