Veryser, Lieselotte et al. published their research in BioMed Research International in 2016 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Related Products of 18836-52-7

Quantitative in vitro and in vivo evaluation of intestinal and blood-brain barrier transport kinetics of the plant N-alkylamide pellitorine was written by Veryser, Lieselotte;Bracke, Nathalie;Wynendaele, Evelien;Joshi, Tanmayee;Tatke, Pratima;Taevernier, Lien;De Spiegeleer, Bart. And the article was included in BioMed Research International in 2016.Related Products of 18836-52-7 The following contents are mentioned in the article:

Objective: To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant Nalkylamide pellitorine. Methods: Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut after oral administration, and (3) the BBB in mice after i.v. and intracerebroventricular administration. A validated bioanal. UPLC-MS2 methodwas used to quantify pellitorine. Results: Pellitorine was able to cross the Caco-2 cell monolayer from the apical-to-basolateral and from the basolateral-to-apical side with apparent permeability coefficients between 0.6 · 10^^-^^5 and 4.8 · 10^^-^^5 cm/h and between 0.3 · 10^^-^^5 and 5.8 · 10^^-^^5 cm/h, resp. In rats, a serum elimination rate constant of 0.3 h^^-^^1 was obtained. I.v. injection of pellitorine in mice resulted in a rapid and high permeation of pellitorine through the BBB with a unidirectional influx rate constant of 153μL/(g·min). In particular, 97% of pellitorine reached the brain tissue, while only 3% remained in the brain capillaries. An efflux transfer constant of 0.05 min-1 was obtained. Conclusion: Pellitorine shows a good gut permeation and rapidly permeates the BBB once in the blood, indicating a possible role in the treatment of central nervous system diseases. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Related Products of 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Related Products of 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ramya, R. et al. published their research in Research Journal of Biotechnology in 2020 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

In silico investigation of quorum quenching potential of Piper nigrum, Piper betle and Coscinium fenestratum on Vibrio cholerae was written by Ramya, R.;Gopinath, S. M.. And the article was included in Research Journal of Biotechnology in 2020.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Current study investigates the ability of phytoligands to inhibit biofilm formation in multidrug resistant, clin. isolated V. cholerae. Methanolic extracts of Coscinium fenestratum, Piper betle and Piper nigrum were checked for their antibiofilm activity. The herbal bioactive compounds were screened by LC/MS-MS and binding potentials against the drug targets were predicted by mol. docking. The extracts exhibited a MIC in a range of 0.1mg/mL- 0.15mg/mL. Reduction of EPS and rhamnolipids was found to be 84.27%, 67% and 46.6% resp. by C. fenestratum, P. betle and P. nigrum. Six major proteins were selected as putative targets. of the 6 targets, the phytoligands were effective against AphB, HapR, LuxO and Vps. Berberine present in C. fenestratum (binding energy of -8.6 kcal/mol), Eugenol in P. betle (binding energy – 6.2 kcal/mol) and Piperidine in P. nigrum (binding energy -4.0 kcal/mol) demonstrated effective min. binding energy against AphB. In silico anal. has revealed that the QS proteins of V. cholerae targeted by the phytoligands might destabilize the biofilm on d. dependent manner based on inhibition of surface adhesion and attenuating the virulence factors leading to quorum sensing inhibition. Berberine and Eugenol can be used as quorum inhibitors for attenuation of MDR V. cholerae at sub inhibitory concentration of 50μg/mL. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Guo, Ziyan et al. published their research in Journal of Pharmacy and Pharmacology in 2019 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.COA of Formula: C14H25NO

Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L. was written by Guo, Ziyan;Xu, Jie;Xia, Jianhua;Wu, Zi;Lei, Jiachuan;Yu, Jianqing. And the article was included in Journal of Pharmacy and Pharmacology in 2019.COA of Formula: C14H25NO The following contents are mentioned in the article:

Objectives : To explore effective extraction method and to find active constituents, we investigated the biol. activity of three extracts and isolated active compounds from the fruits of Piper longum L. Methods : Three extracts from the fruits were obtained by reflux, ultrasonic and supercritical fluid extraction, resp. Active compounds were isolated by the bioassay-guided method. The anti-inflammatory activity, antiproliferation activity and cytotoxicity were evaluated. The apoptosis was detected by Hoechst 33258 staining assay. The relevant proteins were investigated by Western blot assay. Key findings : The anti-inflammatory activity and cytotoxicity of supercritical fluid extract (SE) were stronger than those of the other two extracts Among all isolated compounds, the anti-inflammatory activity of eight compounds was stronger than that of indomethacin, and compounds 8, 9, 11, 14 and 15 were found to possess anti-inflammatory effect for the first time. Compounds 1, 2, 3 and 14 exhibited significant cytotoxicity against cancer cells. SE and piperine were found to reduce colony formation, inhibit cell migration and promote apoptosis through increasing cleaved PARP and the ratio of Bax/Bcl-2. Conclusions : The anti-inflammatory and antitumor effects of SE were better than those of the other two extracts The compounds responsible for the activity were elucidated. SE and piperine inhibit cell growth through apoptosis. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7COA of Formula: C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.COA of Formula: C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Saetang, Jirakrit et al. published their research in Pharmaceutical Biology (Abingdon, United Kingdom) in 2022 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Formula: C14H25NO

The attenuation effect of low piperine Piper nigrum extract on doxorubicininduced toxicity of blood chemical and immunological properties in mammary tumor rats was written by Saetang, Jirakrit;Tedasen, Aman;Sangkhathat, Surasak;Sangkaew, Natnaree;Dokduang, Sirinapa;Prompat, Napat;Taraporn, Siriporn;Graidist, Potchanapond. And the article was included in Pharmaceutical Biology (Abingdon, United Kingdom) in 2022.Formula: C14H25NO The following contents are mentioned in the article:

Many natural extracts have been shown to minimize the toxicity of doxorubicin (Dox). Low piperine Piper nigrum L. (Piperaceae) extract (PFPE) is a natural extract containing many types of antioxidants that may reduce Dox toxicities. To evaluate the effect of PFPE in attenuating the side effects of Dox. Tumor-bearing Sprague Dawley rats were divided into five groups including normal, vehicle, 100 mg/kg BW of PFPE plus 2 mg/kg BW of Dox (P100 Dox), 100 mg/kg BW of PFPE plus 2 mg/kg BW of Dox (P200 Dox) and Dox. Rats were treated with Dox and/or PFPE three times/ week for 4 wk. Tumor burden, blood parameters, weight of internal organs and immunol. data were investigated. The addition of 200 mg/kg PFPE significantly restored the levels of AST from 174.60 ± 45.67 U/L in the Dox group near to normal levels at 109.80 ± 4.99 U/L. The combination of PFPE and Dox also decreased the levels of CXCL7, TIMP-1, sICAM-1 and L-selectin about 1.4-1.6-fold compared to Dox group. Feeding rats with 200 mg/kg BW of PFPE combination with Dox slightly increased Th1 from 161.67 ± 14.28 cells in Dox group to 200.75 ± 5.8 cells meanwhile suppressed Treg from 3088 ± 78 cells in Dox to 2561 ± 71 cells. This study showed that PFPE ameliorated Dox toxicity in many aspects indicating the role of antioxidant and other substances in the extract on toxicity attenuation. This suggested the using of PFPE may be valuable for Dox treated patients. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Formula: C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Formula: C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Tine, Yoro et al. published their research in Chemistry & Biodiversity in 2017 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Safety of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Chemical diversity and antimicrobial activity of volatile compounds from Zanthoxylum zanthoxyloides Lam. according to compound classes, plant organs and Senegalese sample locations was written by Tine, Yoro;Diop, Abdoulaye;Diatta, William;Desjobert, Jean-Marie;Boye, Cheikh Saad Bouh;Costa, Jean;Wele, Alassane;Paolini, Julien. And the article was included in Chemistry & Biodiversity in 2017.Safety of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

The chem. diversity of Zanthoxylum zanthoxyloides growing wild in Senegal was studied according to volatile compound classes, plant organs and sample locations. The composition of fruit essential oil was investigated using an original targeted approach based on the combination of gas chromatog. (GC) and liquid chromatog. (LC) both coupled with mass spectrometry (MS). The volatile composition of Z. zanthoxyloides fruits exhibited relative high amounts of hydrocarbon monoterpenes (24.3 – 55.8%) and non-terpenic oxygenated compounds (34.5 – 63.1%). The main components were (E)-β-ocimene (12.1 – 39%), octyl acetate (11.6 – 21.8%) and decanol (9.7 – 15.4%). The GC and GC/MS profiling of fruit essential oils showed a chem. variability according to geog. locations of plant material. The LC/MS/MS anal. of fruit oils allowed the detection of seven coumarins in trace content. The chem. composition of fruit essential oils was compared with volatile fractions of leaves and barks (root and trunk) from the same plant station. Hexadecanoic acid, germacrene D and decanal were identified as the major constituents of leaves whereas the barks (root and trunk) were dominated by pellitorine (85.8% and 57%, resp.), an atypic linear compound with amide group. The fruit essential oil exhibited interesting antimicrobial activities against Staphylococcus aureus and Candida albicans, particularly the alc. fraction of the oil. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Safety of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Safety of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hussain, Khalid et al. published their research in Pharmacologyonline in 2009 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 18836-52-7

Cytotoxicity evaluation and characterization of chloroform extract of leaf of Piper sarmentosum possessing antiangiogenic activity was written by Hussain, Khalid;Ismail, Zhari;Sadikun, Amirin;Ibrahim, Pazillah. And the article was included in Pharmacologyonline in 2009.Application of 18836-52-7 The following contents are mentioned in the article:

The chloroform extract of leaves of Piper sarmentosum, a traditional medicinal plant, have shown promising antiangiogenic activity, IC50 45 μg/mL. Therefore, present study aimed to investigate the extract to rule out the probability of the involvement of cell death in the activity, and characterize the extract using colorimetry, gas chromatog. time of the flight mass spectrometry (GC-TOFMS) and high performance liquid chromatog. (HPLC). Different concentrations of the extract were evaluated by MTT cell-viability assay using human hepatic carcinoma cell line (HepG2) and human umbilical vascular endothelial cell line (HUVEC). Vincristine sulfate (IC50 0.016 μg/mL) was used as a pos. control. The extract exhibited IC50 76.24 μg/mL for HepG2 cells and 64.43 μg/mL for HUVEC. These IC50 values were found to be higher than IC50 (45 μg/mL) of the extract for antiangiogenic activity. The extract was analyzed for total amide content using colorimetric method and to characterize two main peaks by GC-TOFMS which were found to be pellitorine and sarmentine. In HPLC anal., the extract was found to have pellitorine (0.020 mg/g) and sarmentine (0.006 mg/g). Both of these markers exhibited 30 % antiangiogenic activity. The results of this study indicate that the extract inhibits angiogenesis without changing morphol. and viability of vascular endothelial cells. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Application of 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Lieder, Barbara et al. published their research in Molecules in 2019 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Formula: C14H25NO

Biological evaluation of natural and synthesized homovanillic acid esters as inhibitors of intestinal fatty acid uptake in differentiated Caco-2 cells was written by Lieder, Barbara;Hans, Joachim;Hentschel, Fabia;Geissler, Katrin;Ley, Jakob. And the article was included in Molecules in 2019.Formula: C14H25NO The following contents are mentioned in the article:

The modulation of fatty acid uptake by enterocytes represents a promising target for body weight maintenance. Recent results demonstrated that the trigeminal active compounds capsaicin, nonivamide, and trans-pellitorine dose-dependently reduce fatty acid uptake in differentiated Caco-2 cells as a model for the intestinal barrier. However, non-pungent alternatives have not been investigated and structural determinants for the modulation of intestinal fatty acid uptake have not been identified so far. Thus, based on the previous results, we synthesized 23 homovanillic acid esters in addition to the naturally occurring capsiate and screened them for their potential to reduce intestinal fatty acid uptake using the fluorescent fatty acid analog Bodipy-C12 in differentiated Caco-2 cells as an enterocyte model. Whereas pre-incubation with 100μM capsiate did not change fatty acid uptake by Caco-2 enterocytes, a maximum inhibition of -47% was reached using 100μM 1-methylpentyl-2-(4-hydroxy-3-methoxy-phenyl)acetate. Structural anal. of the 24 structural analogs tested in the present study revealed that a branched fatty acid side chain, independent of the chain length, is one of the most important structural motifs associated with inhibition of fatty acid uptake in Caco-2 enterocytes. The results of the present study may serve as an important basis for designing potent dietary inhibitors of fatty acid uptake. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Formula: C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Formula: C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Singh, Deepak Kumar et al. published their research in Journal of Biologically Active Products from Nature in 2020 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Recommanded Product: 18836-52-7

Studies on Pellitorine Production and Antioxidant Activity of Explant Specific Calli of Anacyclus pyrethrum was written by Singh, Deepak Kumar;Babbar, Shashi Bhushan;Mir, Bilal Ahmad. And the article was included in Journal of Biologically Active Products from Nature in 2020.Recommanded Product: 18836-52-7 The following contents are mentioned in the article:

Anacyclus pyrethrum is a perennial and procumbent herb of immense medicinal value, largely due to the presence of an array of therapeutically active alkaloids such as Pellitorine. In this study, cotyledon, hypocotyl and root explants of A. pyrethrum were tested for their callogenic response and subsequent pellitorine accumulation on MS medium supplemented with 2, 4-D. At elevated concentrations of 2,4-D cotyledonary explants showed higher callogenic response than root and hypocotyl but at lower concentrations of 2,4-D, the results were observed the opposite. The calli of all the treatments were harvested after 30, 45, 60 and 75 days of inoculation. The calli of all the three explants were tested for pellitorine content after 30d, 45d, 60d, and 75d of the culture. Interestingly, calli of cotyledons harvested at 75d of inoculation accumulated maximum pellitorine content of 94.50μg/g dry weight indicating that the old callus is harvested for maximum economic benefit and large scale production of pellitorine. Antioxidant activity of calli raised from different explants and harvested after different time intervals were examined using DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Thus, this study reports an efficient and reproducible protocol for successful callus induction from various explants of A. pyrethrum for large scale production of pellitorine and evaluation of antioxidant activities. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Recommanded Product: 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ahoua, Angora Remi Constant et al. published their research in Planta Medica in 2019 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Anti-inflammatory and Quinone Reductase-Inducing Compounds from Beilschmiedia mannii was written by Ahoua, Angora Remi Constant;Monteillier, Aymeric;Borlat, Frederic;Ciclet, Olivier;Marcourt, Laurence;Nejad Ebrahimi, Samad;Kone, Mamidou Witabouna;Bonfoh, Bassirou;Christen, Philippe;Cuendet, Muriel. And the article was included in Planta Medica in 2019.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Previous studies on the therapeutic potential of plant species found in the diet of chimpanzees living in tai national park have shown that they could be potential candidates for the search of new mols. useful for humans. Based on the screening of some of these plants, the fruits of beilschmiedia mannii, whose dichloromethane extract showed cancer chemopreventive properties, were selected. Bioactivity-guided fractionation of the extract resulted in the isolation and identification of two pyrones, including desmethoxydihydromethysticin ( 1), found in a natural source for the first time, and a new congener, beilschmiediapyrone ( 2), as well as five known alkamides ( 3 – 7). Their structures were established by using nmr spectroscopy and mass spectrometry methods. The isolated compounds were evaluated for their cancer chemopreventive potential by using quinone reductase induction and nuclear factor-kappa b inhibition tests in hepa 1c1c7 and hek-293/nf- b-luc cells, resp. Among them, compounds 1and 2were the most active. The concentrations to double the quinone reductase activity were 7.5 mum for compound 1and 6.1 mum for compound 2. Compounds 1and 2inhibited nuclear factor-kappa b with ic 50values of 2.1 and 3.4 mum, resp. These results are promising with regard to cancer chemoprevention, especially because this plant is also used for cooking by the local population around the tai forest. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Liang, Jian et al. published their research in Food Research International in 2021 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Chemical analysis and classification of black pepper (Piper nigrum L.) based on their country of origin using mass spectrometric methods and chemometrics was written by Liang, Jian;Sun, Jianghao;Chen, Pei;Frazier, Jared;Benefield, Virginia;Zhang, Mengliang. And the article was included in Food Research International in 2021.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

The current study applied gas chromatog.-mass spectrometry (GC-MS), liquid chromatog.-mass spectrometry (LC-MS), and thermal desorption direct anal. in real-time mass spectrometry (TD-DART-MS) methods to the anal. of black pepper (Piper nigrum L.) samples from different countries. The black pepper powder samples were analyzed directly by TD-DART-MS without any extraction, but for GC-MS and LC-MS methods, a methanol extraction procedure was employed before the anal. Various compounds, such as piperamides and terpenes, were detected. Partial least squares-discriminant anal. (PLS-DA) was used to classify black pepper samples based on their origins. Total ion mass spectrum (TMS) data profiles from GC-MS, LC-MS, and TD-DART-MS methods were constructed and evaluated for the performance of classification. A cubic-root data transformation was tested in the data preprocessing and found to be effective for improving the classification rates. The average classification rates of PLS-DA models with GC-MS-cubic-root-TMS, LC-MS-cubic-root-TMS, and DART-MS-cubic-root-TMS data representations were 94.1 ± 0.6%, 87.7 ± 0.6%, and 97.0 ± 0.3% resp., for 100-time bootstrapped-Latin-partition cross-validation. This study presents for the first time the anal. of plant-based food materials by using TD-DART-MS, and it has been demonstrated as a simple and high-throughput method for classification studies. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics