Category: 2447-79-2

Yasmin, Nasima published the artcileA simple one-pot synthesis of 2-aryl-5-alkyl-substituted oxazoles by Cs₂CO₃-mediated reactions of aromatic primary amides with 2,3-dibromopropene, Category: amides-buliding-blocks, the publication is Synlett (2009), 2825-2827, database is CAplus.

A simple and efficient method for the synthesis of 2-aryl-5-alkyl-substituted oxazoles has been developed. A series of 2,5-disubstituted oxazoles were synthesized in a single step by Cs₂CO₃-mediated reactions of aromatic primary amides with 2,3-dibromopropene.

Synlett published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C16H14O6, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Queen, Z. Edel published the artcileThe GC MS study of one ayurvedic preparation Amrithamehari churnam, Computed Properties of 2447-79-2, the publication is International Journal of Pharmaceutical Sciences Review and Research (2016), 39(2), 169-172, database is CAplus.

Amrithamehari churnam is an Ayurvedic formulation for the treatment of diabetes, weight loss and bladder disorders. The present study deals with the GC MS anal. of of Amrithamehari churnam. Fifty different peaks were observed indicating various bimols. It was observed that there is an indication of the presence of some compounds such as Pyridinium, 1-(2-hydrazino-2-oxoethyl)-, chloride, Arsonous dichloride, methyl-, 1-Dodecane, 2-Methoxy-4-vinylphenol, 1-Undecanol, 1-hexadecanol, Artumerone, Tumerone, Curlone, 4-Isoquinolinecarboxylic acid, 2, 3, 5, 6, 7, 8-hexahydro-3-oxo-, 1-Docosene, Squalene, á-Sitosterol, Benzenepropanoic acid, 3, 5-bis(1,1-dimethylethyl)-4-hydroxy etc. The medicinal values of each compound have similarity with that of the main drug, Amrithamehari churnam. Further work is in progress to prove the efficacy of this drug by standard methods.

International Journal of Pharmaceutical Sciences Review and Research published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Computed Properties of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Owston, Nathan A. published the artcileIridium-catalyzed conversion of alcohols into amides via oximes, Application In Synthesis of 2447-79-2, the publication is Organic Letters (2007), 9(1), 73-75, database is CAplus and MEDLINE.

The iridium catalyst [Ir(Cp*)Cl₂]₂ is effective for the rearrangement of oximes to furnish amides. The reaction has been combined with catalytic transfer hydrogenation between an alc. and alkene to allow the conversion of alcs. into amides in a one-pot process.

Organic Letters published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Application In Synthesis of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Owston, Nathan A. published the artcileHighly efficient ruthenium-catalyzed oxime to amide rearrangement, Quality Control of 2447-79-2, the publication is Organic Letters (2007), 9(18), 3599-3601, database is CAplus and MEDLINE.

A wide range of aldoximes has been converted into the corresponding amides using the ruthenium-based catalyst Ru(PPh₃)₃(CO)H₂/dppe/TsOH. The amides were generated in high yield and selectivity, with catalyst loading as low as 0.04 mol %.

Organic Letters published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Quality Control of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Datta, Bandita published the artcileSilica chloride-catalyzed microwave-assisted efficient and selective one-pot synthesis of amides from aldehydes, Recommanded Product: 2,4-Dichlorobenzamide, the publication is Bulletin of the Korean Chemical Society (2012), 33(7), 2129-2130, database is CAplus.

A one-pot selective conversion of aromatic aldehydes to amides with NH₂OH.HCl by catalytic SiO₂-Cl in a microwave reactor at 100 W was presented. This synthesis is suitable for electron-withdrawing and electron-donating aldehydes. The developed protocol has advantages of short reaction time and high yields, utilizes an efficient and recyclable heterogeneous catalyst, and follows green chem. norms.

Bulletin of the Korean Chemical Society published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Recommanded Product: 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Gholivand, Khodayar published the artcileNew N-nicotinyl and N-2,4-dichlorobenzoyl phosphorictriamides: syntheses, spectroscopic study, and crystal structures, Recommanded Product: 2,4-Dichlorobenzamide, the publication is Main Group Chemistry (2008), 7(4), 251-269, database is CAplus.

New phosphoric triamides, ArC(O)NHP(O)(NR₂)₂ [R = iBu, Ar = 3-pyridyl (1), Ph (6); Ar = 2,4-Cl₂C₆H₄, R = Et (2), n-Pr (3), n-Bu (4), iBu (5)] were synthesized and characterized by ¹H, ¹³C, ³¹P NMR, IR spectroscopy and elemental anal. It is noteworthy that as far as is known there were not any efforts for the synthesis of phosphoric triamides with nicotinamide substituent up to now and compound 1 is the 1st example of this series. Compounds 1, 5, 6 indicate the coupling of diastereotopic CH₂ protons with each other, CH proton and the corresponding P atom in ¹H NMR spectra as well as two separated signals for the two CH₃ moieties in ¹³C NMR spectra. The ¹H NMR spectrum of compound 5 demonstrates long-range ⁶J_P,H coupling constant Also, long-range ⁴J_H,H coupling constant appeared for the aromatic protons of mols. 1–4. Also, the structures were determined for 2–4 by x-ray crystallog.

Main Group Chemistry published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Recommanded Product: 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Gholivand, Khodayar published the artcileNew phosphoric triamides: chlorine substituents effects and polymorphism, Safety of 2,4-Dichlorobenzamide, the publication is Heteroatom Chemistry (2010), 21(3), 168-180, database is CAplus.

New phosphoric triamides 1–10 were synthesized by the reaction of N-2,4-dichlorobenzoyl phosphoramidic dichloride with various cyclic aliphatic amines, and the products were characterized by ¹H, ¹³C, ³¹P NMR, and IR spectroscopy and elemental anal. Surprisingly, the ¹H NMR spectra of compounds 1–7 demonstrate long-range ⁴J(H,H) coupling constant from 1.5 to 1.9 Hz. Comparison of the NMR and IR spectra of N-benzoyl, N-4-chlorobenzoyl, and N-2,4-dichlorobenzoyl phosphoric triamide analogs indicates that N-2,4-dichlorobenzoyl derivatives have the most upfield δ(³¹P) and the highest ν(C=O) values. The crystal structures of 3, 4, 6, 6a, and 10 have been determined by x-ray crystallog. Interestingly, the structures of 6 and 6a are polymorphic. All structures form dimers through strong, intermol. -P=O···H-N- hydrogen bonds. The dimers connect to each other via weak C-H···Cl and C-H···OH- bonds to produce two-dimensional polymeric chains for 4 and three-dimensional networks for others. Among new synthesized N-2,4-dichlorobenzoyl phosphoric triamides, one indicated polymorphism. All structures were characterized by ¹H, ¹³C, ³¹P NMR, and IR spectroscopy and elemental anal. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:168-180, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20592.

Heteroatom Chemistry published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Safety of 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Gholivand, Khodayar published the artcileN-2,4-dichlorobenzoyl phosphoric triamides: Synthesis, spectroscopic and x-ray crystallography studies, Synthetic Route of 2447-79-2, the publication is Journal of Chemical Sciences (Bangalore, India) (2010), 122(4), 549-559, database is CAplus.

New phosphoric triamides (R¹P(O)Cl₂, 1; R¹P(O)(OH)₂, 2; R¹P(O)(NHCH₂CH=CH₂)₂, 3; R¹P(O)[NHCH(CH₃)₂]₂, 4; R¹P(O)[NH-C(CH₃)₃]₂, 5; R¹P(O)(NHCH₂-C₄H₃O)₂, 6; R¹P(O)(NHCH₂C₆H₅)₂, 7; R¹P(O)[N(CH₃)(CH₂C₆H₅)]₂, 8; R¹P(O)[NHCH(CH₃)(C₆H₅)]₂, 9; R¹ = 2,4-Cl₂-C₆H₃C(O)NH) were synthesized by the reaction of N-2,4-dichlorobenzoyl phosphoramidic dichloride with various cyclic aliphatic amines and the products were characterized by ¹H, ¹³C, ³¹P NMR, IR spectroscopy and elemental anal. Surprisingly, the ¹H NMR spectrum of 2 indicated long range ⁶J (P, H) coupling constant = 1.3, 1.4 Hz and those of mols. 3, 4, 6–8 display long-range ⁴J (H, H) coupling constants (1.8-1.9 Hz) for the coupling of aromatic protons in 2,4-dichlorophenyl rings. ¹H NMR spectra indicated ³J (PNCH) for enantiotopic and diastereotopic benzylic CH₂ protons in compounds 7 and 8. The spectroscopic data of newly synthesized compounds were compared with those related N-benzoyl derivatives The structures of compounds 5, 8 and 10 (2,4-Cl₂-C₆H₃C(O)NHP(O)[N(CH₂CH(CH₃)₂)₂]₂) have been determined by x-ray crystallog. The structures form centrosym. dimers through intermol. strong -P=O…H-N-hydrogen bonds. The dimers connect to each other via rather strong and weak C-H…O plus weak C-H…Cl H-bonds to produce a 1-D network for 5 while 3-D polymeric chains for 8 and 10.

Journal of Chemical Sciences (Bangalore, India) published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Synthetic Route of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Odiaka, Timothy I. published the artcileNew tricarbonyl(amido-substituted-1,3-diene)iron complexes, Related Products of amides-buliding-blocks, the publication is Journal of Organometallic Chemistry (1985), 288(2), C30-C32, database is CAplus.

Benzamides I (R = H, 2-OH, 4-MeO, 3-MeO, 3,5-(MeO)₂, 4-Cl, 2,4-Cl₂) added reversibly to the dienyl rings of II (R¹ = H, MeO; n = 1, 2) to give III.

Journal of Organometallic Chemistry published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Related Products of amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Bose, D. Subhas published the artcileTrocCl mediated efficient synthesis of nitriles from primary amides, SDS of cas: 2447-79-2, the publication is Synthetic Communications (2000), 30(16), 3047-3052, database is CAplus.

To establish a rapid conversion method of primary amides to nitriles, various types of carboxamides were treated with 2,2,2-trichloroethyl chloroformate and Et₃N, as a dehydrating agent to obtain the desired nitriles in 82-95% yields.

Synthetic Communications published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, SDS of cas: 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics