Category: 70298-88-3

Andres, J. Ignacio; Alonso, Jose M.; Fernandez, Javier; Iturrino, Laura; Martinez, Pedro; Meert, Theo F.; Sipido, Victor K. published their research in Bioorganic & Medicinal Chemistry Letters on December 16 ,2002. The article was titled 《2-(Dimethylaminomethyl)-tetrahydroisoxazolopyridobenzazepine derivatives. Synthesis of a new 5-HT2C antagonist with potential anxiolytic properties》.Application of 70298-88-3 The article contains the following contents:

The synthesis of 2-(dimethylaminomethyl)-2,3,3a,8-tetrahydroisoxazolo[3,2-a]pyrido[3,4-c]-[2]benzazepine and 2-(dimethylaminomethyl)-2,3,3a,8-tetrahydroisoxazolo[3,2-a]pyrido[3,2-c]-[2]benzazepine via a new route is reported. The affinities for several receptors as well as the m-chlorophenylpiperazine antagonistic activity of the compounds synthesized are described. After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Application of 70298-88-3)

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Application of 70298-88-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

The author of 《CuCl-catalyzed ortho trifluoromethylation of arenes and heteroarenes with a pivalamido directing group》 were Cai, Shangjun; Chen, Chao; Sun, Zelin; Xi, Chanjuan. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2013. Recommanded Product: 2,2-Dimehtyl-N-pyridin-3-yl-propionamide The author mentioned the following in the article:

The CuCl catalyzed direct trifluoromethylation of sp2 C-H bonds has been realized, using the Togni reagent as the CF3 source. This reaction achieves the goal of regio-selectively converting C-H into C-CF3 with ecol. and readily available starting materials. After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Recommanded Product: 2,2-Dimehtyl-N-pyridin-3-yl-propionamide)

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. The methylamines occur in small amounts in some plants. Many polyfunctional amines (i.e., those having other functional groups in the molecule) occur as alkaloids in plants—for example, mescaline, 2-(3,4,5-trimethoxyphenyl)ethylamine; the cyclic amines nicotine, atropine, morphine, and cocaine; and the quaternary salt choline, N-(2-hydroxyethyl)trimethylammonium chloride, which is present in nerve synapses and in plant and animal cells.Recommanded Product: 2,2-Dimehtyl-N-pyridin-3-yl-propionamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

The author of 《Simultaneous infrared-ultrasound irradiation in organic synthesis: acylation of amines alcohols and amino alcohols》 were Luna-Mora, Ricardo Alfredo; Ortega-Jimenez, Fernando; Rios-Guerra, Hulme; Garcia-Estrada, Jose Guadalupe; Perez-Flores, Francisco Javier; Gonzalez-Carrillo, Jessica; Torres-Reyes, Angeles; Moreno-Gonzalez, Linda; Martinez-Zaldivar, Alejandro; Penieres-Carrillo, Jose Guillermo. And the article was published in Journal of the Mexican Chemical Society in 2019. Product Details of 70298-88-3 The author mentioned the following in the article:

The acylation of both aliphatic and aromatic amines, alcs. and amino alcs. by simultaneous IR-ultrasound irradiation (SIUI) in solvent-free conditions in short reaction times and with good to excellent yields was achieved. The results obtained with SIUI and for thermal, IR and ultrasound energy sources are compared. This is the first report regarding to the application of SIUI in acylation reactions. In the part of experimental materials, we found many familiar compounds, such as 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Product Details of 70298-88-3)

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Product Details of 70298-88-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

COA of Formula: C10H14N2OOn June 7, 1999, Iwaki, Takehiko; Yasuhara, Akito; Sakamoto, Takao published an article in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry. The article was 《Novel synthetic strategy of carbolines via palladium-catalyzed amination and arylation reaction》. The article mentions the following:

The four parent carbolines I-IV and their C-5 or C-9 methylsulfonyl derivatives were prepared by Pd-catalyzed intramol. arylation reaction of ortho-bromo-substituted anilinopyridines which were prepared by Pd-catalyzed amination of iodobenzenes with aminopyridines. Carbazole and its C-9 methylsulfonyl derivative were also prepared by the same method. After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3COA of Formula: C10H14N2O)

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime.Typically the presence of an amine functional group is deduced by a combination of techniques, including mass spectrometry as well as NMR and IR spectroscopies. 1H NMR signals for amines disappear upon treatment of the sample with D2O. In their infrared spectrum primary amines exhibit two N-H bands, whereas secondary amines exhibit only one.COA of Formula: C10H14N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

《Crystal structure of 2,2-dimethyl-N-(pyridin-3-yl)propanamide》 was written by El-Hiti, Gamal A.; Smith, Keith; Hegazy, Amany S.; Alanazi, Saud A.; Kariuki, Benson M.. Application of 70298-88-3 And the article was included in Acta Crystallographica, Section E: Crystallographic Communications on April 30 ,2015. The article conveys some information:

In the title compound, C10H14N2O, the pyridine ring is inclined to the mean plane of the amide moiety [N-C(=O)C] by 17.60 (8)°. There is an intramol. C-H···O hydrogen bond present involving the carbonyl O atom. In the crystal, mols. are linked via N-H···N hydrogen bonds, forming chains propagating along [100]. The tert-Bu group is disordered over two sets of sites with a refined occupancy ratio of 0.758 (12):0.242 (12). After reading the article, we found that the author used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Application of 70298-88-3)

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. Amines have a free lone pair with which they can coordinate to metal centers. Amine–metal bonds are weaker because amines are incapable of backbonding, but they are still important for sensing applications.While stronger than hydrogen bonds, amine–metal bonds are still weaker than both covalent and ionic bonds.Application of 70298-88-3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics