Category: 89-73-6

Product Details of 89-73-6《Accurate calculation of equilibrium constants using potentiometric titrations》 was published in 2022. The authors were Phansi, Piyawan;Ferreira, Sergio L. C.;Cerda, Victor, and the article was included in《TrAC, Trends in Analytical Chemistry》. The author mentioned the following in the article:

The aim of this work is to revise some programs, which are used to obtain accurate equilibrium constants using several chained programs. For this purpose, the AutoAnal. software is very useful to perform the exptl. work, including potentiometric titrations The POTENtit program allows detecting some problems in the data obtained with AutoAnal. along the exptl. work, like the presence of metals in the sample and the carbonation of the titrant. This program also allows obtaining the standard potential of the working electrode, and the ionic product of the solvent under the used exptl. ionic strength. Finally the MINIPOT program allows refining the results obtained, both for the calibration of the electrodes (E0, jH, JOH, pKs, and g) and for the constants equilibrium (HqLp or MqLp). These three mentioned programs have been updated in order to run under the Windows 10 environment.N,2-Dihydroxybenzamide (cas: 89-73-6) were involved in the experimental procedure.

N,2-Dihydroxybenzamide(cas: 89-73-6) has also been shown to be active against wild-type strains of Candida glabrata, but not against resistant mutants. Product Details of 89-73-6 This drug may have therapeutic potential for bone cancer and metabolic disorders such as obesity.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ding, Lingzhi;Zhou, Jiamin;Ye, Lisa;Sun, Yechao;Jiang, Zhenglin;Gan, Deqiang;Xu, Lihua;Luo, Qianqian;Wang, Guohua published 《PPAR-γ Is Critical for HDAC3-Mediated Control of Oligodendrocyte Progenitor Cell Proliferation and Differentiation after Focal Demyelination》. The research results were published in《Molecular Neurobiology》 in 2020.Formula: C7H7NO3 The article conveys some information:

Disruption of remyelination contributes to neurodegeneration and cognitive impairment in chronically disabled patients. Valproic acid (VPA) inhibits histone deacetylase (HDAC) function and probably promotes oligodendrocyte progenitor cell (OPC) proliferation and differentiation; however, the relevant mol. mechanisms remain unknown. Here, focal demyelinating lesions (FDLs) were generated in mice by two-point stereotactic injection of lysophosphatidylcholine (LPC) into the corpus callosum. Cognitive functions, sensorimotor abilities and histopathol. changes were assessed for up to 28 days post-injury with or without VPA treatment. Primary OPCs were harvested and used to study the effect of VPA on OPC differentiation under inflammatory conditions. VPA dose-dependently attenuated learning and memory deficits and robustly protected white matter after FDL induction, as demonstrated by reductions in SMI-32 and increases in myelin basic protein staining. VPA also promoted OPC proliferation and differentiation and increased subsequent remyelination efficiency by day 28 post-FDL induction. VPA treatment did not affect HDAC1, HDAC2 or HDAC8 expression but reduced HDAC3 protein levels. In vitro, VPA improved the survival of mouse OPCs and promoted their differentiation into oligodendrocytes following lipopolysaccharide (LPS) stimulation. LPS caused OPCs to overexpress HDAC3, which translocated from the cytoplasm into the nucleus, where it directly interacted with the nuclear transcription factor PPAR-γ and neg. regulated PPAR-γ expression. VPA decreased the expression of HDAC3 and promoted remyelination and functional neurol. recovery after FDL. These findings may support the use of strategies modulating HDAC3-mediated regulation of protein acetylation for the treatment of demyelination-related cognitive dysfunction. The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Formula: C7H7NO3It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wang, Yuanyuan;Jin, Tianlin;Wang, Xue;Liang, Dacheng published 《Phytosterol alterations responding to ROS inhibitors by GC-MS in Arabidopsis》. The research results were published in《Pakistan Journal of Botany》 in 2022.Computed Properties of C7H7NO3 The article conveys some information:

Phytosterols, essential components of cellular membrane integrity, play an important role in plant growth, development, and responses to various types of stressors. Emerging studies have proposed that phytosterols are a result of adaptation to the aerobic environment during evolution. We reasoned that phytosterols could dramatically respond to changes in external reactive oxygen species (ROS) levels. The levels of five phytosterols were measured by gas chromatog.-mass spectrometry (GC-MS) after Arabidopsis plants were treated with the ROS-altering drugs 2′-3′-dideoxycytidine (DDC), H2O2, Catalase (CAT), diphenyleneiodonium (DPI), and salicylhydroxamic acid (SHAM) and auxin transport inhibitors 2,3,5-triiodobenzoic acid (TIBA) and 1-N-naphthylphthalamic acid (NPA). We found that all redox-altering agents can dramatically reduce sterol levels, whereas CAT and NPA can partly increase them. Our results establish a link between redox balance and sterol level alteration. The experimental procedure involved many compounds, such as N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Computed Properties of C7H7NO3It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Cao, Shiming;Cao, Yijun;Ma, Zilong;Liao, Yinfei;Zhang, Xiaolin published 《Structural and electronic properties of bastnaesite and implications for surface reactions in flotation》. The research results were published in《Journal of Rare Earths》 in 2020.Recommanded Product: N,2-Dihydroxybenzamide The article conveys some information:

The structural and electronic properties of bastnaesite were studied by using the first-principles method based on the d. functional theory (DFT). The geometry structure of bastnaesite was first optimized, and then the Mulliken populations, electron d. and d. of states were calculated and further analyzed in detail. The calculation results reveal that it mainly ruptures along the ionic Ce-O and Ce-F bonds during the cleavage of bastnaesite, leaving ≈Ce⁺, ≈F^– and ≈CO^–₃ dangling bonds exposed on the cleavage surface of bastnaesite. Combined with contact angle measurement, surface complexation theory and XPS anal., the implications of structural and electronic properties on bastnaesite flotation reactions were studied. The hydration of exposed strong ionic bond on cleavage surface results in hydrophilic surface. According to surface complexation theory, the formed surface groups are ≈CeOH⁰, ≈CO₃H⁰ and ≈FH⁰ groups. The investigated metal ions and flotation reagents complex with surface ≈CeOH⁰ groups, while ≈CO₃H⁰ and ≈FH⁰ groups are not involved in the complexation. The high activity of Ce atoms facilitates these surface reactions.N,2-Dihydroxybenzamide (cas: 89-73-6) were involved in the experimental procedure.

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Recommanded Product: N,2-DihydroxybenzamideIt inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Name: N,2-Dihydroxybenzamide《Estrogen dampens central cannabinoid receptor 1-mediated neuroexcitation and pressor response in conscious female rats》 was published in 2022. The authors were Yao, Fanrong;Abdel-Rahman, Abdel A., and the article was included in《Biochemical Pharmacology (Amsterdam, Netherlands)》. The author mentioned the following in the article:

Activation of the rostral ventrolateral medulla (RVLM) cannabinoid receptor-1 (CB1R) causes neuronal nitric oxide synthase (nNOS)-dependent increases in sympathetic activity, blood pressure (BP) and heart rate (HR) in male rats. However, it remains unknown if the CB1R-mediated neurochem. and cardiovascular responses are influenced by the ovarian sex hormones, particularly estrogen (E2). Therefore, we studied the effects of intra-RVLM CB1R activation (WIN 55,212-2) on BP and HR in conscious female rats under the following hormonal states: (1) highest E2 level (proestrus sham-operated, SO); (2) E2-deprivation (ovariectomized, OVX); (3) OVX with E2 replacement (OVXE2). Intra-RVLM WIN55,212-2 elicited dose (100-400 pmol) dependent pressor and tachycardic responses, in OVX rats, which replicated the reported responses in male rats. However, in SO and OVXE2 rats, the CB1R-mediated pressor response was attenuated and the tachycardic response reverted to bradycardic response. The neurochem. findings suggested a key role for the upregulated RVLM sympathoexcitatory mols. phosphorated protein kinase B, phosphorated nNOS and reactive oxygen species in the exaggerated CB1R-mediated BP and HR responses in OVX rats, and an E2-dependent dampening of these responses. The intra-RVLM WIN55212-2-evoked cardiovascular and neurochem. responses were CB1R-mediated because they were attenuated by prior CB1R blockade (AM251). Our findings suggest that attenuation of RVLM neuroexcitation and oxidative stress underlies the protection conferred by E2, in female rats, against the CB1R-mediated adverse cardiovascular effects. To complete the study, the researchers used N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Name: N,2-DihydroxybenzamideIt inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Application In Synthesis of N,2-Dihydroxybenzamide《Cytochrome c and the transcription factor ABI4 establish a molecular link between mitochondria and ABA-dependent seed germination》 was published in 2022. The authors were Racca, Sofia;Gras, Diana E.;Canal, M. Victoria;Ferrero, Lucia V.;Rojas, Bruno E.;Figueroa, Carlos M.;Ariel, Federico D.;Welchen, Elina;Gonzalez, Daniel H., and the article was included in《New Phytologist》. The author mentioned the following in the article:

During germination, seed reserves are mobilised to sustain the metabolic and energetic demands of plant growth. Mitochondrial respiration is presumably required to drive germination in several species, but only recently its role in this process has begun to be elucidated. Using Arabidopsis thaliana lines with changes in the levels of the respiratory chain component cytochrome c (CYTc), we investigated the role of this protein in germination and its relationship with hormonal pathways. Cytochrome c deficiency causes delayed seed germination, which correlates with decreased cyanide-sensitive respiration and ATP production at the onset of germination. In addition, CYTc affects the sensitivity of germination to abscisic acid (ABA), which neg. regulates the expression of CYTC-2, one of two CYTc-encoding genes in Arabidopsis. CYTC-2 acts downstream of the transcription factor ABSCISIC ACID INSENSITIVE 4 (ABI4), which binds to a region of the CYTC-2 promoter required for repression by ABA and regulates its expression. The results show that CYTc is a main player during seed germination through its role in respiratory metabolism and energy production In addition, the direct regulation of CYTC-2 by ABI4 and its effect on ABA-responsive germination establishes a link between mitochondrial and hormonal functions during this process. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) is a hydroxamic acid that inhibits the activity of p-hydroxybenzoic acid (PHBA) reductase, an enzyme involved in the conversion of PHBA to benzoic acid. Application In Synthesis of N,2-Dihydroxybenzamide The compound has been shown to inhibit mitochondrial membrane potential and mitochondrial functions, leading to cell death.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yuan, Yu;Shan, Xiaosong;Men, Weidong;Zhai, Hexin;Qiao, Xiaoxia;Geng, Lianting;Li, Chunhui published 《The effect of crocin on memory, hippocampal acetylcholine level, and apoptosis in a rat model of cerebral ischemia》. The research results were published in《Biomedicine & Pharmacotherapy》 in 2020.Product Details of 89-73-6 The article conveys some information:

Although the memory- improving effect of crocin has been suggested by previous evidences, the association between this effect and hippocampal acetylcholine (Ach) level and apoptosis is not well investigated. This study aimed to determine the protective effects of crocin on memory, hippocampal Ach level, and apoptosis in a rat model of cerebral ischemia. Male Wistar rats were divided into sham group received saline, and other 3 groups underwent 4-vessel occlusion brain ischemia (4VOI), received oral administration of either saline or crocin in doses of 30 mg/day and 60 mg/day for 7 days. Outcomes were memory, determined by radial eight-arm maze (RAM) task and Morris water maze (MWM) test, Ach release in the dorsal hippocampus (evaluated by microdialysis-HPLC) and apoptosis (investigated by TUNEL assay). 4VOI impaired memory reduced dorsal hippocampus Ach level, and induced apoptosis. Crocin, significantly improved the memory (F = 343.20; P < 0.001 for RAM error choices and F = 182.5; P < 0.0001 for MWM), increased Ach level (F = 115.1; P < 0.001) and prevented hippocampal neuronal apoptosis (W = 183.50; P < 0.001) as compared statistically by ANOVA test. Crocin can be suggested as a promising therapy for ischemic cerebrovascular accidents by its memory preserving, Ach-increasing, and neuroprotective effects. To complete the study, the researchers used N,2-Dihydroxybenzamide (cas: 89-73-6) .

N,2-Dihydroxybenzamide(cas: 89-73-6) can be used:To prepare phenylboronic acid-based bioconjugates for chromatographic applications;As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.Product Details of 89-73-6

Reference:
Amide – Wikipedia,
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S., Nalumpang;T., Poti;K., Akimitsu published 《Effect of salicylhydroxamic acid on mycelial growth and baseline sensitivity to azoxystrobin in Phytophthora infestans causing potato late blight in Thailand》. The research results were published in《International Journal of Agricultural Technology》 in 2021.Recommanded Product: N,2-Dihydroxybenzamide The article conveys some information:

Late blight of potato caused by Phytophthora infestans is proved to be an aggressive pathogen. Azoxystrobin, a broad spectrum quinone outside inhibitor (QoI), has been used in potato cultivation, but not directly recommended to use to control late blight disease. In this study, a suitable method to determine the sensitivity of P. infestans against azoxystrobin and azoxystrobin sensitivity to P. infestans population was recorded in Chiang Rai and Chiang Mai, Thailand. The toxicity of SHAM was proved a nessary of SHAM addition to artificial media for an efficient determination of azoxystrobin sensitivity. Increased of SHAM concentration led increased mycelial inhibition. SHAM at concentration of 5 to 10μg/mL showed less effect to mycelia growth of six representative isolates with means of 5.33 to 12.06% inhibition. Both concentrations of SHAM were applied with azoxystrobin for pre-in vitro sensitivity determination Effective concentration for 50% inhibition (EC50) of azoxystrobin without SHAM was 0.0873μg/mL, and the sensitivity were significantly increased in azoxystrobin amended with SHAM at 5 and 10μg/mL for 55.34 and 70.90%, resp. SHAM at 5μg/mL was used for in vitro sensitivity assay to azoxystrobin. The thirty-six isolates of P. infestans were determined their azoxystrobin sensitivities based on EC₅₀ evaluation. The mean EC50 value of isolate was 0.0531μg/mL and ranged from 0.0005 to 0.4415μg/mL indicating that azoxystrobin was very effective to control the mycelial growth of P. infestans isolated from Chiang Rai and Chiang Mai, Thailand. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) can be used:To prepare phenylboronic acid-based bioconjugates for chromatographic applications;As a ligand to synthesize Fe(III), Cu(II), Ni(II) and Zn(II) complexes.Recommanded Product: N,2-Dihydroxybenzamide

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Luo, Liping;Xu, Longhua;Meng, Jinping;Lu, Jiahui;Wu, Houqin published 《New insights into the mixed anionic/cationic collector adsorption on ilmenite and titanaugite: An in situ ATR-FTIR/2D-COS study》 in 2021. The article was appeared in 《Minerals Engineering》. They have made some progress in their research.HPLC of Formula: 89-73-6 The article mentions the following:

Elucidation of the co-adsorption characteristics of multiple functional groups will help to screen suitable reagents to improve the floatability and comprehensive utilization of valuable minerals. Herein, salicylhydroxamic acid (SHA), an anionic collector with two functional groups, mixed with a cationic collector dodecylamine (DDA) in ilmenite-titanaugite flotation system was in-depth studied mainly using in-situ attenuated total reflectance Fourier transform IR spectroscopy (ATR-FTIR) combined with the two-dimensional correlation spectroscopic anal. (2D-COS) and XPS. The highest flotation separation performance, at pH 8-9, can be achieved using the SHA/DDA complex with a molar ratio of 6:1. Moreover, at. force microscope (AFM) anal. ulteriorly proved the selectivity of the mixed SHA/DDA collector in the ilmenite-titanaugite flotation system. In-situ ATR-FTIR combined with 2D-COS gave the characteristic sequential adsorption and interaction with the functional groups related to SHA/DDA, which was further confirmed in the results of XPS. The preferred adsorption configuration for the adsorption of the mixed collector were drew to explain the flotation separation between ilmenite and titanaugite. It is predictable that the detailed study into the hybrid collectors with multiple functional groups will provide new insights into the design, synthesis and development of more-powerful collectors. And N,2-Dihydroxybenzamide (cas: 89-73-6) was used in the research process.

N,2-Dihydroxybenzamide(cas: 89-73-6) has also been shown to be active against wild-type strains of Candida glabrata, but not against resistant mutants. HPLC of Formula: 89-73-6 This drug may have therapeutic potential for bone cancer and metabolic disorders such as obesity.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Travis, Jordan R.;Van Trieste, Gerard P. III;Zeller, Matthias;Zaleski, Curtis M. published 《Crystal structures of two dysprosium-aluminium-sodium [3.3.1] metallacryptates that form two-dimensional sheets》 in 2020. The article was appeared in 《Acta Crystallographica, Section E: Crystallographic Communications》. They have made some progress in their research.Category: amides-buliding-blocks The article mentions the following:

The two [3.3.1] metallacryptate complexes, namely, poly[[μ3-acetato-hexakis(μ-N,N-dimethylformamide)bis(N,N-dimethylformamide)bis[salicylhydroximato(2-)]heptakis[salicylhydroximato(3-)]hexaaluminium(III)dysprosium(III)pentasodium(I)] N,N-dimethylformamide tetrasolvate monohydrate], [DyAl6Na5(OAc)(Hshi)2(shi)7(DMF)8]·4DMF·H2O or {[DyAl6Na5(C7H5NO3)2(C7H4NO3)7(C2H3O2)(C3H7NO)8]·4C3H7NO·H2O}n, 1, and poly[[di-μ4-acetato-nonakis(μ-N,N-dimethylformamide)octakis(N,N-dimethylformamide)tetrakis[salicylhydroximato(2-)]tetradecakis[salicylhydroximato(3-)]dodecaaluminium(III)didysprosium(III)decasodium(I)] N,N-dimethylformamide 6.335-solvate], [DyAl6Na5(OAc)(Hshi)2(shi)7(DMF)8.5]2·6.335DMF or {[Dy2Al12Na10(C7H5NO3)4(C7H4NO3)14(C2H3O2)2(C3H7NO)17]·6.335C3H7NO}n, 2, where shi3- is salicylhydroximate and DMF is N,N-dimethylformamide, both consist of an aluminum-based metallacryptand. In 1 and 2, the metallacryptand encapsulates a dysprosium(III) ion in the central cavity, and the resulting metallacryptates are connected to each other via sodium-DMF linkages to generate a two-dimensional sheet. The metallacryptates of 1 and 2 are the three-dimensional analogs of metallacrowns as the metallacryptates contain a metal-nitrogen-oxygen cyclic repeat unit throughout the complexes. For 1 the building block of the two-dimensional sheet is comprised of only one type of metallacryptate, which is connected to four neighboring metallacryptates via four sodium-DMF linkages. In 2, the building block is a dimeric unit of two metallacryptates. Each dimeric metallacryptate unit is connected to four other dimeric units via six sodium-DMF linkages. The two metallacryptates of each dimeric unit can be considered enantiomers of each other. In both 1 and 2, chirality is imparted to the metallacryptate due to the Λ and Δ propeller configurations of the four octahedral aluminum ions of the metallacryptand shell.N,2-Dihydroxybenzamide (cas: 89-73-6) were involved in the experimental procedure.

N,2-Dihydroxybenzamide(cas: 89-73-6) is widely used for a variety of roles in biology and medicine as a chelating therapy.Category: amides-buliding-blocksIt inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths.

Reference:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics