Category: 91-00-9

An article Reactions between 5-Nitroso-1,3-diphenyltetrazolium Salts and Electron-Rich Arenes, Amines, Thiophenol, Sulfoxides, and Thioanisole WOS:000460122900006 published article about NITROSO-COMPOUNDS; OXIDATION; REDUCTION; COMPLEX; SYSTEM in [Matsukawa, Yuta; Hirashita, Tsunehisa; Araki, Shuki] Nagoya Inst Technol, Grad Sch Engn, Life Sci & Appl Chem, Showa Ku, Gokiso Cho, Nagoya, Aichi 4668555, Japan in 2019.0, Cited 35.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Name: Diphenylmethanamine

A series of reactions between 5-nitroso-1,3-diphenyltetrazolium tetrafluoroborate and methoxybenzenes, amines, thiols, sulfoxides, and sulfides, most of which are generally accepted as being inert to nitroso groups, is reported here. The tetrazolium-activated nitroso functionality is capable of oxidizing the aforementioned substrates to give the corresponding oxidized products, and the nitroso tetrazolium itself is transformed into the corresponding amide or hydroxyamide, depending on the nature of the reaction partners. In the case of thioanisole, an addition product was obtained.

COA of Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Authors Joseph, D; Park, MS; Lee, S in ROYAL SOC CHEMISTRY published article about H BOND-CLEAVAGE; N-C CLEAVAGE; SECONDARY AMIDES; CARBOXAMIDES; ACTIVATION in [Joseph, Devaneyan; Park, Myeong Seong; Lee, Sunwoo] Chonnam Natl Univ, Dept Chem, Gwangju 61186, South Korea in 2021.0, Cited 39.0. Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

N-Acyl lactam amides, such as benzoylpyrrolidin-2-one, benzoylpiperidin-2-one, and benzoylazepan-2-one reacted with amines in the presence of DTBP and TBAI to afford the transamidated products in good yields. The reactions were conducted under aqueous conditions and good functional group tolerance was achieved. Both aliphatic and aromatic primary amines displayed good activity under metal-free conditions. A radical reaction pathway is proposed.

Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Joseph, D; Park, MS; Lee, S or send Email.

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Amide – Wikipedia,
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Computed Properties of C13H13N. Linciano, P; Pozzi, C; dello Iacono, L; di Pisa, F; Landi, G; Bonucci, A; Gul, S; Kuzikov, M; Ellinger, B; Witt, G; Santarem, N; Baptista, C; Franco, C; Moraes, CB; Muller, W; Wittig, U; Luciani, R; Sesenna, A; Quotadamo, A; Ferrari, S; Pohner, I; Cordeiro-Da-Silva, A; Mangani, S; Costantino, L; Costi, MP in [Linciano, Pasquale; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Costantino, Luca; Costi, Maria Paola] Univ Modena & Reggio Emilia, Dipartimento Sci Vita, Via Campi 103, I-41125 Modena, Italy; [Pozzi, Cecilia; dello Iacono, Lucia; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Mangani, Stefano] Univ Siena, Dipartimento Biotecnol Chim & Farm, Via Aldo Moro 2, I-53100 Siena, Italy; [Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa] Fraunhofer Inst Mol Biol & Appl Ecol Screening Po, D-22525 Hamburg, Germany; [Santarem, Nuno; Baptista, Catarina] Inst Mol & Cell Biol, P-4150180 Porto, Portugal; [Santarem, Nuno; Baptista, Catarina] Univ Porto, Inst Invest & Inovacao Saude, P-4150180 Porto, Portugal; [Franco, Caio; Moraes, Carolina B.] CNPEM, Lab Nacl Biociencias LNBio, BR-13083100 Campinas, SP, Brazil; [Mueller, Wolfgang; Wittig, Ulrike] HITS, Sci Databases & Visualizat Grp, D-69118 Heidelberg, Germany; [Wittig, Ulrike] HITS, Mol & Cellular Modeling Grp, D-69118 Heidelberg, Germany; [Franco, Caio; Moraes, Carolina B.] Univ Sao Paulo, Dept Microbiol, Inst Biomed Sci, BR-05508900 Sao Paulo, SP, Brazil published Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections in 2019.0, Cited 57.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

2-Amino-benzo[d]thiazole was identified as a new scaffold for the development of improved pteridine reductase-1 (PTR1) inhibitors and anti-trypanosomatidic agents. Molecular docking and crystallography guided the design and synthesis of 42 new benzothiazoles. The compounds were assessed for Trypanosoma brucei and Leishmania major PTR1 inhibition and in vitro activity against T. brucei and amastigote Leishmania infantum. We identified several 2-amino-benzo[d]thiazoles with improved enzymatic activity (TbPTR1 IC50 = 0.35 mu M; LmPTR1 IC50 = 1.9 mu M) and low mu M antiparasitic activity against T. brucei. The ten most active compounds against TbPTR1 were able to potentiate the antiparasitic activity of methotrexate when evaluated in combination against T. brucei, with a potentiating index between 1.2 and 2.7. The compound library was profiled for early ADME toxicity, and 2-amino-N-benzylbenzo[d]thiazole-6-carboxamide (4c) was finally identified as a novel potent, safe, and selective anti-trypanocydal agent (EC50 = 7.0 mu M). Formulation of 4c with hydroxypropyl-beta-cyclodextrin yielded good oral bioavailability, encouraging progression to in vivo studies.

Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.. Computed Properties of C13H13N

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

COA of Formula: C13H13N. He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB in [He, Junhui; Su, Lebin; Wu, Shaofeng; Liu, Lixin; Yin, Shuang-Feng; Zhou, Yongbo] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China; [Dong, Jianyu] Hunan First Normal Univ, Dept Educ Sci, Changsha 410205, Peoples R China published Selective Oxidative Cleavage of 3-Methylindoles with Primary Amines Affording Quinazolinones in 2020.0, Cited 77.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A selective functionalization of C-C.C bonds toward N-C=O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.

Welcome to talk about 91-00-9, If you have any questions, you can contact He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB or send Email.. COA of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Iron-Catalyzed Direct Transformation of Benzylic Amines into Carbonyl Compounds in Water WOS:000482516100016 published article about DIRECT N-ALKYLATION; OXIDATIVE DEAMINATION; BOND-CLEAVAGE; METAL-FREE; MECHANISM; QUINAZOLINONES; HYDROGENATION; ALCOHOLS; ACIDS; SCOPE in [Minakawa, Maki; Sasaki, Takashi] Yamagata Univ, Dept Appl Chem Chem Engn & Biochem Engn, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan in 2019, Cited 32. Recommanded Product: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Fe-catalyzed direct transformation of benzylic amines into carbonyl compounds was performed in H2O. The reaction of benzylic amines with formaldehyde in the presence of FeCl3 center dot 6H(2)O in H2O afforded the corresponding carbonyl compounds (80 degrees C to reflux conditions; 14 examples, up to 94% yield). O-18-labeling experiments indicated that the O atom in the generated carbonyl is derived from H2O.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Environmentally benign decarboxylative N-, O-, and S-acetylations and acylations WOS:000598242900016 published article about EFFICIENT RECYCLABLE CATALYST; DBN TETRAPHENYLBORATE SALTS; DIRECT AMIDATION; CARBOXYLIC-ACIDS; HIGHLY EFFICIENT; SILICA-GEL; ALCOHOLS; AMINES; PHENOLS; SOLVENT in [Ghosh, Santanu; Purkait, Anisha; Jana, Chandan K.] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India in 2020.0, Cited 76.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Computed Properties of C13H13N

An operationally simple and general method for acetylation and acylation of a wide variety of substrates (amines, alcohols, phenols, thiols, and hydrazones) has been reported. Meldrum’s acid and its derivatives have been used as an air-stable, non-volatile, cost-effective, and easy to handle acetylating/acylating agent. Easily separable byproducts (CO2 and acetone) allowed the isolation of analytically pure acetylated products without the requirement of work-up and any chromatography.

Welcome to talk about 91-00-9, If you have any questions, you can contact Ghosh, S; Purkait, A; Jana, CK or send Email.. Computed Properties of C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

COA of Formula: C13H13N. I found the field of Chemistry very interesting. Saw the article Allylation and alkylation of oxindoleketimines via imine umpolung strategy published in 2021.0, Reprint Addresses Shen, MH; Xu, DF (corresponding author), Changzhou Univ, Sch Pharm, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Jiangsu, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine.

When treated with an alkoxide base like t-BuOK in aprotic solvent, N-diphenylmethyl imino oxindoles, made conveniently through condensation of corresponding isatins with N-diphenylmethyl amine, are deprotonated to form azaallyl anions. Allylation and alkylation of this type of intermediates proceed smoothly with diverse C-electrophiles. Acidic work up finishes 3-amino-3-allyl/alkyl oxindoles. The overall transformation equals to an umpolung process at the C3 of isatins. (c) 2021 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

COA of Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Consecutive Intermolecular Reductive Amination/Asymmetric Hydrogenation: Facile Access to Sterically Tunable Chiral Vicinal Diamines and N-Heterocyclic Carbenes WOS:000495739600018 published article about HIGHLY ENANTIOSELECTIVE HYDROGENATION; CATALYTIC ASYMMETRIC DIAMINATION; MESO-AZIRIDINES; MANNICH REACTION; IMINES; AMINOLYSIS; ADDITIONS; ALKENES; DESIGN; LIGAND in [Chen, Ya; Pan, Yixiao; He, Yan-Mei; Fan, Qing-Hua] ICCAS, Univ Chinese Acad Sci, CAS Key Lab Mol Recognit & Funct, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China; [Fan, Qing-Hua] Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China in 2019.0, Cited 82.0. Recommanded Product: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A highly enantioselective iridium- or ruthenium-catalyzed intermolecular reductive amination/asymmetric hydrogenation relay with 2-quinoline aldehydes and aromatic amines has been developed. A broad range of sterically tunable chiral N,N’-diaryl vicinal diamines were obtained in high yields (up to 95%) with excellent enantioselectivity (up to >99% ee). The resulting chiral diamines could be readily transformed into sterically hindered chiral N-heterocyclic carbene (NHC) precursors, which are otherwise difficult to access. The usefulness of this synthetic approach was further demonstrated by the successful application of one of the chiral vicinal diamines and chiral NHC ligands in a transition-metal-catalyzed asymmetric Suzuki-Miyaura cross-coupling reaction and asymmetric ring-opening cross-metathesis, respectively.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Computed Properties of C13H13N. I found the field of Pharmacology & Pharmacy very interesting. Saw the article Optimizing Targeted Inhibitors of P-Glycoprotein Using Computational and Structure-Guided Approaches published in 2019, Reprint Addresses Wise, JG; Vogel, PD (corresponding author), Southern Methodist Univ, Dept Biol Sci, 6501 Airline Rd, Dallas, TX 75205 USA.; Wise, JG; Vogel, PD (corresponding author), Southern Methodist Univ, Ctr Drug Discovery Design & Delivery, 6501 Airline Rd, Dallas, TX 75205 USA.; Wise, JG; Vogel, PD (corresponding author), Southern Methodist Univ, Ctr Sci Computat, 6501 Airline Rd, Dallas, TX 75205 USA.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine.

Overexpression of ABC transporters like P-glycoprotein (P-gp) has been correlated with resistances in cancer chemotherapy. Intensive efforts to identify P-gp inhibitors for use in combination therapy have not led to clinically approved inhibitors to date. Here, we describe computational approaches combined with structure-based design to improve the characteristics of a P-gp inhibitor previously identified by us. This hit compound represents a novel class of P-gp inhibitors that specifically targets and inhibits P-gp ATP hydrolysis while not being transported by the pump. We describe here a new program for virtual chemical synthesis and computational assessment, ChemGen, to produce hit compound variants with improved binding characteristics. The chemical syntheses of several variants, efficacy in reversing multidrug resistance in cell culture, and biochemical assessment of the inhibition mechanism are described. The usefulness of the computational predictions of binding characteristics of the inhibitor variants is discussed and compared to more traditional structure-based approaches.

Computed Properties of C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Wise, JG; Nanayakkara, AK; Aljowni, M; Chen, G; De Oliveira, MC; Ammerman, L; Olengue, K; Lippert, AR; Vogel, PD or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: Diphenylmethanamine. In 2019.0 ACS CATAL published article about C BOND-CLEAVAGE; METAL-FREE; CARBONYLATION REACTIONS; CARBON-MONOXIDE; ALKYL IODIDES; HALIDES; CHEMISTRY; COUPLINGS; ALKENES; SALTS in [Lu, Bin; Cheng, Ying; Chen, Li-Yan; Chen, Jia-Rong; Xiao, Wen-Jing] Cent China Normal Univ, Int Joint Res Ctr Intelligent Biosensing Technol, Key Lab Pesticides & Chem Biol, Minist Educ,Coll Chem, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China; [Xiao, Wen-Jing] Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China in 2019.0, Cited 79.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A visible light-induced and exogenous photo-sensitizer-free, copper-catalyzed radical aminocarbonylation of cycloketone oxime esters with CO gas and amines is developed. The mild catalytic system involving CuCl and N,N,N-tridentate ligand shows good reactivity and chemo-selectivity, and tolerates a wide range of cycloketone oxime esters and alkyl/aryl amines, giving the corresponding cyanoalkylated amides in moderate to good yields. Preliminary mechanistic studies suggest that the reaction involves a Cu-I/(CuCuIII)-Cu-II/-based catalytic cycle and radical intermediate.

Welcome to talk about 91-00-9, If you have any questions, you can contact Lu, B; Cheng, Y; Chen, LY; Chen, JR; Xiao, WJ or send Email.. Recommanded Product: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics