Category: 91-00-9

Hahn, G; Kunnas, P; de Jonge, N; Kempe, R in [Hahn, G.; Kempe, R.] Univ Bayreuth, Chair Inorgan Chem II Catalyst Design, Bayreuth, Germany; [Kunnas, P.; de Jonge, N.] INM Leibniz Inst New Mat, Saarbrucken, Germany; [de Jonge, N.] Saarland Univ, Dept Phys, Saarbrucken, Germany published General synthesis of primary amines via reductive amination employing a reusable nickel catalyst in 2019, Cited 54. Recommanded Product: Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Reusable catalysts based on earth-abundant metals with a broad applicability in organic synthesis are a key to a more sustainable production of fine chemicals, pharmaceuticals and agrochemicals. Herein, we report on a nanostructured nickel catalyst for the general and selective synthesis of primary amines via reductive amination, employing ammonia dissolved in water. Our catalyst, which operates at low temperature and pressure, is highly active, reusable and easy to handle. The synthesis from a specific nickel complex and gamma-Al2O3 is straightforward, with the ligand-metal combination of this complex being crucial. Aldehydes (including purely aliphatic ones), aryl-alkyl, dialkyl and diaryl ketones can all be converted smoothly into primary amines. In addition, the amination of pharmaceuticals, bioactive compounds and natural products is demonstrated. Many functional groups-including hydrogenation-sensitive examples-are tolerated. We expect that our findings will inspire others to develop reusable and nanostructured earth-abundant metal catalysts for complex organic transformations.

Welcome to talk about 91-00-9, If you have any questions, you can contact Hahn, G; Kunnas, P; de Jonge, N; Kempe, R or send Email.. Recommanded Product: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Lewis Acid-Catalyzed Nucleophilic Substitutions of Benzylic Alcohols with Sulfamides published in 2021.0. Application In Synthesis of Diphenylmethanamine, Reprint Addresses Nakata, K (corresponding author), Shimane Univ, Dept Chem, Grad Sch Nat Sci & Technol, 1060 Nishikawatsu, Matsue, Shimane 6908504, Japan.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Nucleophilic substitutions of benzylic alcohols with sulfamides were achieved using an FeCl3 Lewis acid catalyst in MeNO2. It was necessary to adjust the reaction conditions to obtain efficient yields depending on the stability of the carbocation intermediates. The reaction could easily be performed, and it was revealed that a variety of diarylmethanols and benzylic alcohols were applicable to the reaction, irrespective of the type and position of the substituents. The sulfamide moieties were easily deprotected and converted into amine groups.

Application In Synthesis of Diphenylmethanamine. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Wang, L; Wang, XW; Hou, HB; Zhu, GQ; Han, ZY; Yang, WY; Chen, X; Wang, QG in [Wang, Liang; Wang, Xiaowu; Hou, Hongbin; Zhu, Guangqian; Han, Zhenyu; Yang, Weiying; Chen, Xiao; Wang, Qinggang] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, Qingdao 266101, Peoples R China; [Zhu, Guangqian; Han, Zhenyu; Yang, Weiying] Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Beijing 100049, Peoples R China published An unsymmetrical binuclear iminopyridine-iron complex and its catalytic isoprene polymerization in 2020.0, Cited 51.0. Application In Synthesis of Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A series of chloride-bridged unsymmetrical mixed Fe(ii)-HS/Fe(ii)-LS binuclear structures has been prepared and characterized. Upon activation with MAO, highly efficient catalytic polymerization of isoprene was achieved, delivering an ultra-high molecular weight (catalyst loading = 2.5 ppm,M-n= 1.8 x 10(6)g mol(-1),M-w/M-n= 1.4).

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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recently I am researching about ACTIVATED RECEPTOR-ALPHA; PPAR-ALPHA; FENOFIBRATE; GROWTH; CELL; DRUGS; MELANOMA; METABOLISM; INHIBITION; PREDICTION, Saw an article supported by the School of Medicine, LSU Health Sciences Center [P20-GM121288-01]; STEPFARM, LLC; Faculty of Biochemistry, Biophysics and Biotechnology of Jagiellonian University-a partner of the Leading National Research Center (KNOW) – Ministry of Science and Higher Education; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [P20GM121288] Funding Source: NIH RePORTER. Recommanded Product: Diphenylmethanamine. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Stalinska, J; Houser, L; Rak, M; Colley, SB; Reiss, K; Jursic, BS. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Structural variations of the benzylphenoxyacetamide (BPA) molecular skeleton were explored as a viable starting point for designing new anti-glioblastoma drug candidates. Hand-to-hand computational evaluation, chemical modifications, and cell viability testing were performed to explore the importance of some of the structural properties in order to generate, retain, and improve desired anti-glioblastoma characteristics. It was demonstrated that several structural features are required to retain the anti-glioblastoma activity, including a carbonyl group of the benzophenone moiety, as well as 4′-chloro and 2,2-dimethy substituents. In addition, the structure of the amide moiety can be modified in such a way that desirable anti-glioblastoma and physical properties can be improved. Via these structural modifications, more than 50 compounds were prepared and tested for anti-glioblastoma activity. Four compounds were identified (HR28, HR32, HR37, and HR46) that in addition to HR40 (PP1) from our previous study, have been determined to have desirable physical and biological properties. These include high glioblastoma cytotoxicity at low mu M concentrations, improved water solubility, and the ability to penetrate the blood brain barrier (BBB), which indicate a potential for becoming a new class of anti-glioblastoma drugs.

Recommanded Product: Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Stalinska, J; Houser, L; Rak, M; Colley, SB; Reiss, K; Jursic, BS or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Naqvi, S; Kumar, M; Kumar, R in [Naqvi, Samya; Kumar, Rachana] CSIR Natl Phys Lab, Adv Mat & Devices Metrol Div, Photovolta Metrol Grp, Dr KS Krishnan Marg, New Delhi 110012, India; [Kumar, Mahesh] CSIR Natl Phys Lab, Adv Mat & Devices Metrol Div, Photon Mat Metrol Grp, Dr KS Krishnan Marg, New Delhi 110012, India published Facile Synthesis and Evaluation of Electron Transport and Photophysical Properties of Photoluminescent PDI Derivatives in 2019.0, Cited 83.0. Recommanded Product: Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Perylenediimides (PDIs) have emerged as potential materials for optoelectronic applications. In the current work, four PDI derivatives, substituted at imide nitrogen with 2,6-diisopropyl phenyl, 2-nitrophenyl, diphenylmethylene, and pentafluorophenyl groups, have been synthesized from perylene 3,4,9,10-tetracarboxylic dianhydride using a facile imidization synthesis process. PDI derivatives have been spectroscopically characterized for their structure and optical properties. Temperature-variable absorption and emission spectroscopy study confirmed the H-aggregation property. H-aggregation along with strong emission suggests the slipped pi-pi stacking of PDI molecules. Electrochemical analysis was performed for their redox behavior and calculation of lowest unoccupied molecular orbital and highest occupied molecular orbital energy levels. Scanning electron microscopy showed the formation of ordered structures. The PDI derivatives showed excellent electron conductivity without doping and 5-10x higher electron mobility than that of state-of-the-art fullerene acceptor phenyl-C-61 -butyric acid methyl ester (PC61BM). Finally, the charge generation and charge transfer phenomenon was studied by transient absorption spectroscopy (TAS). TAS showed ultrafast charge transfer from the poly(3-hexyl)thiophene (P3HT) donor polymer to PDI and formation of long-lived charge-separated states similar to fullerene derivative PC61 BM/P3HT blends. Such PDI derivatives with excellent solubility and photophysical and electronic properties are potential n-type materials to be used in organic electronic devices.

About Diphenylmethanamine, If you have any questions, you can contact Naqvi, S; Kumar, M; Kumar, R or concate me.. Recommanded Product: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Hexacoordinated nickel catalysts containing salicylaldbenzhydrylimine ligand and tetrahydrofuran heterocycle: High catalytic activity and high 1-hexene insert ratios for norbornene (Co)polymerization published in 2020.0. SDS of cas: 91-00-9, Reprint Addresses He, XH (corresponding author), Nanchang Univ, Sch Mat Sci & Engn, 999 Xuefu Ave, Nanchang 330031, Jiangxi, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Three novel hexacoordinated nickel catalysts containing salicylaldbenzhydrylimine ligand and tetrahydrofuran heterocycle, Ni{(THF) (3-R-1) (5-R-2)C6H2(O)CHNCH(C6H5)(2)}(2), (R-1 = Br, R-2 = H, Ni1; R-1 = Br, R-2 = Br, Ni2; R-1 = Cl, R-2 = Cl, Ni3.), were synthesized and their molecular structures were confirmed by X-ray crystallography. Ni1-Ni3 catalysts exhibited high activities (0.53-2.11 x 10(6) g(polymer)/mol(Ni).h) toward norbornene homopolymerization and high activity (0.29-2.62 x 10(5) g(polymer)/mol(Ni).h) to copolymerization of norbornene and 1-hexene. When the 1-hexene feed ratio was changed from 10 to 70%, the 1-hexene content in the obtained copolymers could be controlled to 8.23-26.58%. The Ni3 with R-1 and R-2 were both electron withdrawing groups (-Cl) on the aromatic ring of salicylaldehyde, showed the highest activity as well as the highest 1-hexene insert ratios. At the same time, only a small amount of B(C6F5)(3) cocatalyst (5 x 10(-5) mol) need to be consumed in the copolymerization process. In addition, the obtained copolymers had a high thermal decomposition temperature (T-d > 386 degrees C) and a low glass transition temperature (T-g = 208.67-237.42 degrees C), which showed that the processability of these polymers was improved while the high thermal decomposition temperature was kept. The copolymers also exhibited good solubility in general organic solvents and high optical transparency in the visible region. (C) 2020 Elsevier B.V. All rights reserved.

SDS of cas: 91-00-9. Welcome to talk about 91-00-9, If you have any questions, you can contact He, XH; Duan, YP; Guo, Y; Wang, K; Wu, B; Wen, YF; Zou, JH; Zhu, CY; Huang, SM; Chen, DF or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Product Details of 91-00-9. In 2019 NAT CATAL published article about AQUEOUS AMMONIA; SELECTIVE HYDROGENATION; IRON CATALYSTS; ALKYLATION; ALCOHOLS; KETONES; ACIDS; FURFURYLAMINE; NANOPARTICLES; NITROARENES in [Hahn, G.; Kempe, R.] Univ Bayreuth, Chair Inorgan Chem II Catalyst Design, Bayreuth, Germany; [Kunnas, P.; de Jonge, N.] INM Leibniz Inst New Mat, Saarbrucken, Germany; [de Jonge, N.] Saarland Univ, Dept Phys, Saarbrucken, Germany in 2019, Cited 54. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Reusable catalysts based on earth-abundant metals with a broad applicability in organic synthesis are a key to a more sustainable production of fine chemicals, pharmaceuticals and agrochemicals. Herein, we report on a nanostructured nickel catalyst for the general and selective synthesis of primary amines via reductive amination, employing ammonia dissolved in water. Our catalyst, which operates at low temperature and pressure, is highly active, reusable and easy to handle. The synthesis from a specific nickel complex and gamma-Al2O3 is straightforward, with the ligand-metal combination of this complex being crucial. Aldehydes (including purely aliphatic ones), aryl-alkyl, dialkyl and diaryl ketones can all be converted smoothly into primary amines. In addition, the amination of pharmaceuticals, bioactive compounds and natural products is demonstrated. Many functional groups-including hydrogenation-sensitive examples-are tolerated. We expect that our findings will inspire others to develop reusable and nanostructured earth-abundant metal catalysts for complex organic transformations.

Welcome to talk about 91-00-9, If you have any questions, you can contact Hahn, G; Kunnas, P; de Jonge, N; Kempe, R or send Email.. Product Details of 91-00-9

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Highly Enantioselective Synthesis of Acyclic N,N ‘-Acetals by Chiral Urea Derived from Quinine Catalyzed the Addition of Aryl Amines to Isatin-Derived Ketimines published in 2019.0. Quality Control of Diphenylmethanamine, Reprint Addresses Lin, YJ; Duan, HF (corresponding author), Jilin Univ, Dept Organ Chem, Coll Chem, 2699 Qianjin St, Changchun 130012, Jilin, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

N,N’-Acetals are sensitive compounds, and the challenging asymmetric synthesis of acyclic N,N’-acetals by the general addition of amines to ketimines has never been reported so far. In this study, highly enantioselective addition of aryl amines to isatin-derived ketimines catalyzed by chiral urea derived from quinine was developed. A series of new acyclic N,N’-acetals were constructed by this protocol in high to excellent yields (78-99%) and high to excellent enantioselectivities (76-96% ee).

Quality Control of Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Liu, YX; Wang, JD; Wei, ZL; Cao, JG; Liang, DP; Lin, YJ; Duan, HF or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: Diphenylmethanamine. I found the field of Pharmacology & Pharmacy very interesting. Saw the article 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis published in 2020.0, Reprint Addresses Hoehn, KL (corresponding author), Univ Virginia, Dept Pharmacol, Charlottesville, VA 22908 USA.; Hoehn, KL (corresponding author), Univ Virginia, Dept Med, Charlottesville, VA 22908 USA.; Hoehn, KL (corresponding author), Univ New South Wales, Sch Biotechnol & Biomol Sci, Kensington, NSW 2033, Australia.; Santos, WL (corresponding author), Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA.; Santos, WL (corresponding author), Virginia Tech, Virginia Tech Ctr Drug Discovery, Blacksburg, VA 24061 USA.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine.

Small molecule mitochondrial uncouplers have recently garnered great interest for their potential in treating nonalcoholic steatohepatitis (NASH). In this study, we report the structure-activity relationship profiling of a 6-amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol core, which utilizes the hydroxy moiety as the proton transporter across the mitochondrial inner membrane. We demonstrate that a wide array of substituents is tolerated with this novel scaffold that increased cellular metabolic rates in vitro using changes in oxygen consumption rate as a readout. In particular, compound SHS4121705 (12i) displayed an EC50 of 4.3 mu M in L6 myoblast cells and excellent oral bioavailability and liver exposure in mice. In the STAM mouse model of NASH, administration of 12i at 25 mg kg(-1) day(-1) lowered liver triglyceride levels and improved liver markers such as alanine aminotransferase, NAFLD activity score, and fibrosis. Importantly, no changes in body temperature or food intake were observed. As potential treatment of NASH, mitochondrial uncouplers show promise for future development.

Recommanded Product: Diphenylmethanamine. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Authors Welker, A; Kersten, C; Muller, C; Madhugiri, R; Zimmer, C; Muller, P; Zimmermann, R; Hammerschmidt, S; Maus, H; Ziebuhr, J; Sotriffer, C; Schirmeister, T in WILEY-V C H VERLAG GMBH published article about CORONAVIRUS PAPAIN-LIKE; RESPIRATORY SYNDROME CORONAVIRUS; PNEUMONIA in [Welker, Armin; Sotriffer, Christoph] Justus Maximilians Univ Wurzburg, Inst Pharm & Food Chem, D-97074 Wurzburg, Germany; [Kersten, Christian; Zimmer, Collin; Mueller, Patrick; Zimmermann, Robert; Hammerschmidt, Stefan; Maus, Hannah; Schirmeister, Tanja] Johannes Gutenberg Univ Mainz, Inst Pharmaceut & Biomed Sci, Staudingerweg 5, D-55128 Mainz, Germany; [Mueller, Christin; Madhugiri, Ramakanth; Ziebuhr, John] Justus Liebig Univ Giessen, Inst Med Virol, Schubertstr 81, D-35392 Giessen, Germany in 2021.0, Cited 29.0. HPLC of Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Inhibition of coronavirus (CoV)-encoded papain-like cysteine proteases (PLpro) represents an attractive strategy to treat infections by these important human pathogens. Herein we report on structure-activity relationships (SAR) of the noncovalent active-site directed inhibitor (R)-5-amino-2-methyl-N-(1-(naphthalen-1-yl)ethyl) benzamide (2 b), which is known to bind into the S3 and S4 pockets of the SARS-CoV PLpro. Moreover, we report the discovery of isoindolines as a new class of potent PL(pro)inhibitors. The studies also provide a deeper understanding of the binding modes of this inhibitor class. Importantly, the inhibitors were also confirmed to inhibit SARS-CoV-2 replication in cell culture suggesting that, due to the high structural similarities of the target proteases, inhibitors identified against SARS-CoV PL(pro)are valuable starting points for the development of new pan-coronaviral inhibitors.

Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics