Category: 91-00-9

Computed Properties of C13H13N. He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB in [He, Junhui; Su, Lebin; Wu, Shaofeng; Liu, Lixin; Yin, Shuang-Feng; Zhou, Yongbo] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China; [Dong, Jianyu] Hunan First Normal Univ, Dept Educ Sci, Changsha 410205, Peoples R China published Selective Oxidative Cleavage of 3-Methylindoles with Primary Amines Affording Quinazolinones in 2020.0, Cited 77.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A selective functionalization of C-C.C bonds toward N-C=O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.

Computed Properties of C13H13N. About Diphenylmethanamine, If you have any questions, you can contact He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

In 2021.0 EUR J ORG CHEM published article about PI-ACTIVATED ALCOHOLS; ALLYLIC ALCOHOLS; UNSYMMETRICAL SULFAMIDES; EFFICIENT SYNTHESIS; CHIRAL-AUXILIARY; DIRECT AMINATION; ASYMMETRIC ARYLATION; ALKYLATION REACTION; CONJUGATE ADDITION; SULFONAMIDES in [Oda, Ryoga; Nakata, Kenya] Shimane Univ, Dept Chem, Grad Sch Nat Sci & Technol, 1060 Nishikawatsu, Matsue, Shimane 6908504, Japan in 2021.0, Cited 104.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Name: Diphenylmethanamine

Nucleophilic substitutions of benzylic alcohols with sulfamides were achieved using an FeCl3 Lewis acid catalyst in MeNO2. It was necessary to adjust the reaction conditions to obtain efficient yields depending on the stability of the carbocation intermediates. The reaction could easily be performed, and it was revealed that a variety of diarylmethanols and benzylic alcohols were applicable to the reaction, irrespective of the type and position of the substituents. The sulfamide moieties were easily deprotected and converted into amine groups.

About Diphenylmethanamine, If you have any questions, you can contact Oda, R; Nakata, K or concate me.. Name: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: 91-00-9. Authors Karteek, SD; Reddy, AG; Tej, MB; Rao, MVB in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Karteek, S. Durga] Koneru Lakshmaiah Educ Fdn, Dept Chem, Vaddeswaram 522502, India; [Reddy, A. Gopi] SANA Coll Pharm, Dept Pharm, Kodad 508206, India; [Tej, M. Bhuvan] Sri Ramachandra Med Coll & Res Inst, Dept Pharm, Chennai 600116, Tamil Nadu, India; [Rao, M. V. Basaveswara] Krishna Univ, Dept Chem, Machilipatnam 521001, India in 2021.0, Cited 38.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A new series of fused tricyclic coumarin derivatives were designed, synthesized by a simple and convenient method, starting from 4-hydroxycoumarin and virtually screened by molecular docking on the target protein 3FRZ (PDB ID: 3FRZ), a HCV RNA-dependent RNA polymerase, for potency against hepatitis C virus (HCV). Efficient binding to the target protein was found for most of the synthesized compounds.

Recommanded Product: 91-00-9. About Diphenylmethanamine, If you have any questions, you can contact Karteek, SD; Reddy, AG; Tej, MB; Rao, MVB or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

SDS of cas: 91-00-9. Dodo, K; Kuboki, E; Shimizu, T; Imamura, R; Magarisawa, M; Takahashi, M; Tokuhiro, T; Yotsumoto, S; Asano, K; Nakao, S; Terayama, N; Suda, T; Tanaka, M; Sodeoka, M in [Dodo, Kosuke; Shimizu, Tadashi; Nakao, Shuhei; Terayama, Naoki; Sodeoka, Mikiko] RIKEN Cluster Pioneering Res, Synthet Organ Chem Lab, 2-1 Hirosawa, Wako, Saitama 3510198, Japan; [Dodo, Kosuke; Sodeoka, Mikiko] JST, ERATO, Sodeoka Live Cell Chem Project, 2-1 Hirosawa, Wako, Saitama 3510198, Japan; [Dodo, Kosuke; Shimizu, Tadashi; Takahashi, Masahiro; Sodeoka, Mikiko] Tohoku Univ, IMRAM, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan; [Kuboki, Erika; Magarisawa, Megumi; Tokuhiro, Takuto; Yotsumoto, Satoshi; Asano, Kenichi; Tanaka, Masato] Tokyo Univ Pharm & Life Sci, Sch Life Sci, Lab Immune Regulat, HAC, 1432-1 Horinouchi, Tokyo 1920392, Japan; [Imamura, Ryu; Suda, Takashi] Kanazawa Univ, Canc Res Inst, Div Immunol & Mol Biol, Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan; [Shimizu, Tadashi] Hyogo Univ Hlth Sci, Adv Med Res Ctr, 1-3-6 Minatojima, Kobe, Hyogo 6508530, Japan published Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis in 2019.0, Cited 31.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

The indolylmaleimide (IM) derivative IM-17 shows inhibitory activity against oxidative-stress-induced necrotic cell death and cardioprotective activity in rat ischemia-reperfusion injury models. In order to develop a more potent derivative, we conducted a detailed structure-activity relationship study of IM derivatives and identified IM 93 as the most potent derivative with good water solubility. IM-93 inhibited ferroptosis and NETosis, but not necroptosis or pyroptosis. In contrast, ferrostatin-1 (Fer-1), a ferroptosis inhibitor, did not inhibit NETosis, although the accompanying lipid peroxidation was partially inhibited by Fer-1, as well as by IM-93. Thus, IM derivatives have a unique activity profile and appear to be promising candidates for in vivo application.

SDS of cas: 91-00-9. About Diphenylmethanamine, If you have any questions, you can contact Dodo, K; Kuboki, E; Shimizu, T; Imamura, R; Magarisawa, M; Takahashi, M; Tokuhiro, T; Yotsumoto, S; Asano, K; Nakao, S; Terayama, N; Suda, T; Tanaka, M; Sodeoka, M or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Application In Synthesis of Diphenylmethanamine. Authors Chang, YJ; Cao, M; Chan, JZ; Zhao, CY; Wang, YK; Yang, R; Wasa, M in AMER CHEMICAL SOC published article about in [Chang, Yejin; Cao, Min; Chan, Jessica Z.; Zhao, Cunyuan; Wang, Yuankai; Yang, Rose; Wasa, Masayuki] Boston Coll, Merkert Chem Ctr, Dept Chem, Chestnut Hill, MA 02467 USA in 2021.0, Cited 123.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

We disclose a catalytic method for beta-C(sp(3))-H functionalization of N-alkylamines for the synthesis of enantiomerically enriched beta-substituted amines, entities prevalent in pharmaceutical compounds and used to generate different families of chiral catalysts. We demonstrate that a catalyst system comprising of seemingly competitive Lewis acids, B(C6F5)(3), and a chiral Mg- or Sc-based complex, promotes the highly enantioselective union of N-alkylamines and alpha,beta-unsaturated compounds. An array of delta-amino carbonyl compounds was synthesized under redox-neutral conditions by enantioselective reaction of a N-alkylamine-derived enamine and an electrophile activated by the chiral Lewis acid co-catalyst. The utility of the approach is highlighted by late-stage beta-C-H functionalization of bioactive amines. Investigations in regard to the mechanistic nuances of the catalytic processes are described.

Application In Synthesis of Diphenylmethanamine. About Diphenylmethanamine, If you have any questions, you can contact Chang, YJ; Cao, M; Chan, JZ; Zhao, CY; Wang, YK; Yang, R; Wasa, M or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Water-mediated C-H activation of arenes with secure carbene precursors: the reaction and its application WOS:000487087500017 published article about SULFOXONIUM YLIDES; BOND ACTIVATION; RH(III)-CATALYZED SYNTHESIS; ORGANIC-SYNTHESIS; DIAZO-COMPOUNDS; PRIMARY AMINES; BENZYLAMINES; ANNULATION; ALKYNES; FUNCTIONALIZATION in [Wang, Qiantao; Wu, Yong] Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Sichuan Engn Lab Plant Sourced Drug, Educ Minist,West China Sch Pharm, Chengdu 610041, Sichuan, Peoples R China; Sichuan Univ, Res Ctr Drug Ind Technol, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist,West China Sch Pharm, Chengdu 610041, Sichuan, Peoples R China in 2019, Cited 50. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. COA of Formula: C13H13N

A water-mediated C-H activation using sulfoxonium ylides is reported, providing a general, green and step-economic approach to construct a C-C bond and varieties of useful N-heterocycle scaffolds. Notably, the water-mediated activation, in contrast to that in organic solvents, shows great potential in pharmaceutical, biochemistry and chemical industries.

About Diphenylmethanamine, If you have any questions, you can contact Nie, RF; Lai, RZ; Lv, SY; Xu, YY; Guo, L; Wang, QT; Wu, Y or concate me.. COA of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recently I am researching about ENANTIOSELECTIVE SYNTHESIS; HIGHLY EFFICIENT; LACTAM SYNTHESIS; AMIDES; ACIDS; POLYMERIZATION; HYDROGENATION; HETEROCYCLES; SUBSTITUTION; CAPURAMYCIN, Saw an article supported by the CERCA Program/Generalitat de Catalunya, ICREA; Spanish MINECO [CTQ-2014-60419-R]; AGAURAgencia de Gestio D’Ajuts Universitaris de Recerca Agaur (AGAUR) [2017-SGR-232]; Chinese Research Council (CSC) [2016-06200061, 2019-06870036]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Xie, JN; Li, XT; Kleij, AW. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine. Application In Synthesis of Diphenylmethanamine

A stereoselective amination/cyclization cascade process has been developed that allows for the preparation of a series of unsaturated and substituted caprolactam derivatives in good yields. This conceptually novel protocol takes advantage of the easy access and modular character of vinyl gamma-lactones that can be prepared from simple precursors. Activation of the lactone substrate in the presence of a suitable Pd precursor and newly developed phosphoramidite ligand offers a stereocontrolled ring-opening/allylic amination manifold under ambient conditions. The intermediate (E)-configured epsilon-amino acid can be cyclized using a suitable dehydrating agent in an efficient one-pot, two-step sequence. This overall highly chemo-, stereo- and regio-selective transformation streamlines the production of a wide variety of modifiable and valuable caprolactam building blocks in an operationally attractive way.

About Diphenylmethanamine, If you have any questions, you can contact Xie, JN; Li, XT; Kleij, AW or concate me.. Application In Synthesis of Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

HPLC of Formula: C13H13N. In 2019.0 BIOORG CHEM published article about HUMAN SERUM-ALBUMIN; MOLECULAR-DYNAMICS SIMULATION; MULTIFUNCTIONAL AGENTS; FLAVONOID DERIVATIVES; COUMARIN DERIVATIVES; BETULINIC ACID; DESIGN; INHIBITORS; DISEASE; SERIES in [Shaik, Jeelan Basha; Kandrakonda, Yelamanda Rao; Penumala, Mohan; Zinka, Raveendra Babu; Amooru, Damu Gangaiah] Yogi Vemana Univ, Dept Chem, Kadapa, Andhra Pradesh, India; [Yeggoni, Daniel Pushparaju; Subramanyam, Rajagopal] Univ Hyderabad, Sch Life Sci, Dept Plant Sci, Hyderabad, India; [Kotapati, Kasi Viswanath; Ampasala, Dinakara Rao] Pondicherry Cent Univ, Ctr Bioinformat, Sch Life Sci, Pondicherry, India; [Darla, Mark Manidhar] Sri Venkateswara Univ, Dept Chem, Tirupati, Andhra Pradesh, India in 2019.0, Cited 56.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

In a search for novel multifunctional anti-Alzheimer agents, a congeneric set of seventeen flavone-8-acrylamide derivatives (8a-q) were synthesized and evaluated for their cholinesterase inhibitory, antioxidant, neuroprotective and modulation of A beta aggregation activities. The target compounds showed effective and selective inhibitory activity against the AChE over BuChE. In addition, the target compounds also showed moderate antioxidant activity and strong neuroprotective capacities, and accelerated dosage-dependently the A beta aggregation. Also, we presented here a complete study on the interaction of 8a, 8d, 8e, 8h and 8i with AChE. Through fluorescence emission studies, the binding sites number found to be 1, binding constants were calculated as 2.04 x 10(4), 2.22 x 10(4), 1.18 x 10(4), 9.8 x 10(3) and 3.2 x 10(4) M-1 and free energy change as -5.83, -5.91, -5.51, -5.41 and -6.12 kcal M-1 at 25 degrees C which were well agreed with the computational calculations indicating a strong binding affinity of flavones and AChE. Furthermore, the CD studies revealed that the secondary structure of AChE became partly unfolded upon binding with 8a, 8d, 8e, 8h and 8i.

HPLC of Formula: C13H13N. About Diphenylmethanamine, If you have any questions, you can contact Shaik, JB; Yeggoni, DP; Kandrakonda, YR; Penumala, M; Zinka, RB; Kotapati, KV; Darla, MM; Ampasala, DR; Subramanyam, R; Amooru, DG or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: Diphenylmethanamine. In 2020.0 ANGEW CHEM INT EDIT published article about CARBONYL-COMPOUNDS; DEOXYGENATION; ALCOHOLS; HYDROGENOLYSIS; 1,2-DIOLS; AMINES; HYDROSILYLATION; ACTIVATION; CONVERSION; MECHANISM in [Fang, Huaquan; Oestreich, Martin] Tech Univ Berlin, Inst Chem, Str 17 Juni 115, D-10623 Berlin, Germany in 2020.0, Cited 52.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

The strong boron Lewis acid tris(pentafluorophenyl)borane B(C6F5)(3) is known to catalyze the dehydrogenative coupling of certain amines and hydrosilanes at elevated temperatures. At higher temperature, the dehydrogenation pathway competes with cleavage of the C-N bond and defunctionalization is obtained. This can be turned into a useful methodology for the transition-metal-free reductive deamination of a broad range of amines as well as heterocumulenes such as an isocyanate and an isothiocyanate.

About Diphenylmethanamine, If you have any questions, you can contact Fang, HQ; Oestreich, M or concate me.. Recommanded Product: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recently I am researching about CARBON-CARBON BOND; C-C; TRIPLE BOND; METAL-FREE; CATALYZED NITROGENATION; CYCLIC AMINES; ACTIVATION; ALKYNES; FUNCTIONALIZATION; OXYGENATION, Saw an article supported by the NSF of ChinaNational Natural Science Foundation of China (NSFC) [21706058, 21878072, 21573065]; NSF of Hunan Province [2016JJ1007, 2018JJ3031]. Product Details of 91-00-9. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

A selective functionalization of C-C.C bonds toward N-C=O bonds is realized by an n-Bu4NI-catalyzed reaction of 3-methylindoles with primary amines using TBHP as the unique oxidant. The systematic process involves oxygenation, nitrogenation, ring-opening, and recyclization, affording a broad range of quinazolinones in good to excellent yields.

About Diphenylmethanamine, If you have any questions, you can contact He, JH; Dong, J; Su, LB; Wu, SF; Liu, LX; Yin, SF; Zhou, YB or concate me.. Product Details of 91-00-9

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics