Category: amides-buliding-blocks

ShaikBabu, K. Govinda Raoand published the artcileAcoustic properties of binary liquid mixtures containing N-methyl formamide with anilines at different temperatures, Recommanded Product: N-Methylformamide, the main research area is methylformamide aniline binary liquid mixture acoustic parameter.

Densities (ρ), viscosity (η) and speed of sound (U) values for the liquid mixture systems of N-Methylformamide with Aniline, N-methylaniline and N,N-Dimethylanilinealong with those of pure liquids were measured over the entire mole fraction range at T = 303.15 K, 308.15 K and 313.15 K. From these exptl. determined values, various acoustic parameters such as excess isentropic compressibility (KsE), excess molar volume (VE) and excess free length (LfE), excess Gibb’s free energy (ΔG*E) and excess enthalpy (HE) have been calculated The excess functions have been fitted to the Redlich-Kister type polynomial equation. The presenceofintermol. interactions in these liquid mixtures was confirmed by studying the deviations observed in the excess parameters.

Rasayan Journal of Chemistry published new progress about Binary mixtures, liquid. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Kalimulla, T. published the artcileUltrasonic investigations in binary liquid mixtures of 2-methylcyclohexanone with formamide, n-methylformamide and N,N-dimethylformamide at different temperatures., Synthetic Route of 123-39-7, the main research area is methylcyclohexanone formamide methylformamide DMF ultrasonic investigation binary liquid mixture.

Ultrasonic velocity(U), viscosity (η) and d. (ρ) of binary liquid mixtures 2-methylcyclohexanone with formamide, N-Methylformamide and N,N-Dimethylformamide have been measured at three temperatures 303.15,308.15 and 313.15 K, over the entire composition range. These exptl. data have been used to calculated the excess isentropic compressibility (KsE), excess enthalpy (HE), excess free length (LfE), excess Gibb’s free energy (ΔG*E) and excess molar volume (VmE). The excess values have been fitted to the Redlich-Kister type polynomial equation. The deviations of excess values provide valuable information that allows us to have a better understanding of the structure of liquids and intermol. interactions in liquid mixtures The results of these observations have been interpreted in terms of structural effects of the solvents. Further the exptl. and derived results are analyzed in terms of structural mol. interactions between component mols. with FT-IR spectral studies.

Journal of Pharmaceutical Sciences and Research published new progress about Binary mixtures, liquid. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Synthetic Route of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Warminska, Dorota published the artcileThermophysical study of the binary mixtures of triethyl phosphate with N-methylformamide, N,N-dimethylformamide and N,N-dimethylacetamide – Experimental and theoretical approach, Computed Properties of 123-39-7, the main research area is triethyl phosphate methylformamide dimethylacetamide binary mixture thermophys excess property.

Densities at (293.15, 298.15, 303.15 and 308.15) K, and viscosities and ultrasonic velocities at 298.15 K of binary liquid mixtures of tri-Et phosphate with N-methylformamide, N,N-dimethylformamide and N,N-dimethylacetamide have been measured over the entire range of composition at p = 0.1 MPa. From the exptl. data, values of excess molar volume, excess isentropic compressibility, viscosity deviation and excess Gibbs energy of activation for viscous flow have been calculated These results were fitted to the Redlich-Kister-type polynomial equation. The viscosity deviations and the excess Gibbs energy were found to be pos. for the all systems investigated, while the excess volumes and the excess isentropic compressibilities were neg. for TEP + DMA and for TEP + DMF systems, and pos. for mixtures TEP + NMF. These results were interpreted based on the strength of the specific interaction, size and shape of mols. Mol. dynamics simulations were used to provide a detailed explanation of the differences between the TEP + NMF and other systems, which were ultimately traced to strong hydrogen bonding between NMF and TEP.

Journal of Molecular Liquids published new progress about Binary mixtures, liquid. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Computed Properties of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Bala, D. published the artcileStudy on Thermodynamic and Transport Properties of Binary Liquid Mixtures (N-Methylformamide with Aniline, N-Methylaniline, and N,N-Dimethylaniline) at Various Temperatures, Formula: C2H5NO, the main research area is thermodn transport property binary liquid mixture Nmethylformamide aniline; Nmethylaniline NNdimethylaniline temperature.

Densities (ρ), speeds of sound (u), and viscosities (η) of binary mixtures of N-methylformamide (N-MF) with aniline (A), N-methylaniline (N-MA), and N, N-dimethylaniline (N, N-DMA) including those of pure liquids, over the entire composition range were measured at temperatures (303.15, 308.15, and 313.15 K) and 0.1 MPa. Using the exptl. data, the excess volume (VE), excess isentropic compressibility (κEs), deviation in viscosity (δη), excess partial molar volumes, [V-Em, 1] and [V-Em, 2], and excess partial molar isentropic compressibilities, [K-Es, m, 1] and [K-Es, m, 2] of the components at infinite dilution were calculated The VE results have been analyzed in the terms of Prigogine-Flory-Patterson theory. An anal. of each of the three contributions viz. interactional, free volume and P* to VE shows that free volume effects are neg. for all the binary mixtures FT-IR (Fourier transform IR spectroscopy) properties have been carried out to study the specific interaction such as formation of hydrogen bond between unlike mols. in the binary liquid mixtures; a good agreement is observed among the excess parameters and FT-IR spectroscopic properties.

Russian Journal of Physical Chemistry A published new progress about Binary mixtures, liquid. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Formula: C2H5NO.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yisimayili, Nuermaimaiti published the artcileα-Hydroxylation of α,α-Disubstituted N-tert-Butanesulfinyl Ketimines with Molecular Oxygen: Stereoselective Synthesis of α-Tertiary Hydroxyimines, Related Products of amides-buliding-blocks, the main research area is tertiary hydroxyimine preparation diastereoselective; acyclic ketimine hydroxylation.

The α-tertiary hydroxyimines (Rs/Ss,2R)-ROHC(R1)C=NS(O)t-Bu (R = butan-2-yl, cyclohex-3-en-1-yl, 1-phenylpropyl, etc.; R1 = Ph, 2-propenyl, 2-methoxyphenyl, etc.) were stereoselectively synthesized from enantioenriched N-tert-butanesulfinyl ketimines (Rs/Ss,2R)-RCH(R1)C=NS(O)t-Bu using potassium tert-butoxide, mol. oxygen, and tri-Me phosphite. The stereoselective hydroxylation of acyclic ketimines bearing two sterically similar α-substituents was achieved by controlling the geometry of the metalloenamine intermediates and the facial selectivity of hydroxylation. The synthetic utility of the resulting α-tertiary hydroxyimines was demonstrated through the successful diastereoselective synthesis of highly substituted β-amino alcs.

Organic Letters published new progress about Diastereoselective synthesis. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Related Products of amides-buliding-blocks.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Quintavalla, Arianna published the artcileDiastereoselective Synthesis of Chiral Oxathiazine 2-Oxide Scaffolds as Sulfinyl Transfer Agents, Synthetic Route of 343338-28-3, the main research area is chiral oxathiazine oxide preparation diastereoselective sulfinyl transfer agent.

An efficient diastereoselective route for the preparation of chiral oxathiazine 2-oxide scaffolds as sulfinyl transfer agents, using tert-butanesulfinamide (tBSA) both as the source of chirality and as the precursor to the required nitrogen electron withdrawing group on the scaffold, was developed. This methodol. allows the introduction of different substituents on the chiral scaffold, using com. available reagents and standard synthetic transformations. The synthesized scaffolds were tested in the preparation of enantioenriched sulfinamides, providing results comparable to the sulfinyl transfer agents so far proposed in the literature, and opening the possibility to further elaborate these scaffolds, with the aim to support them on solid phases so to facilitate their recovery and reuse.

Advanced Synthesis & Catalysis published new progress about Diastereoselective synthesis. 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Synthetic Route of 343338-28-3.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sang, Wenjiao published the artcileDegradation of liquid phase N,N-dimethylformamide by dielectric barrier discharge plasma: Mechanism and degradation pathways, Recommanded Product: N-Methylformamide, the main research area is DMF liquid phase degradation dielec barrier discharge wastewater treatment; Degradation pathways; Dielectric barrier discharge (DBD) plasma; Hydroxyl radical; Liquid phase; N,N-dimethylformamide (DMF).

The degradation of liquid phase N,N-dimethylformamide (DMF) using the dielec. barrier discharge (DBD) plasma was studied in the present study. The results showed that 1000 mg L-1 DMF could be degraded by DBD plasma under different input power, treatment time and initial pH values of aqueous solution After 40 min with DBD plasma discharge, 52.2% degradation efficiency was achieved at DMF concentration of 1000 mg L-1 with an input power of 16.19 W under initial pH of 11.14 in aqueous solution, and the energy efficiency of the system was 13.2 mg kJ-1. The removal efficiency decreased with the presence of radical scavenger, manifesting that ·OH plays a critical role in the degradation process. The value of TOC in DMF aqueous solution decreased from 790 mg L-1 to 507 mg L-1 in 40 min, which indicated that DBD plasma has the ability to mineralize a portion of DMF in liquid directly. Addnl., the anal. of FTIR, HPLC and the small mol. organic compounds before and after the DBD plasma degradation indicated that the intermediates of DMF in degradation process were N-methylformamide, methanol, formaldehyde and formic acid, which were finally mineralized into ammonia nitrogen, CO2 and H2O. Moreover, the possible degradation mechanism and pathways were proposed.

Chemosphere published new progress about Dielectric barrier discharge. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Recommanded Product: N-Methylformamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhang, Lei published the artcileTotal Synthesis of (-)-Alstofolinine A through a Furan Oxidation/Rearrangement and Indole Nucleophilic Cyclization Cascade, Safety of (S)-2-Methylpropane-2-sulfinamide, the main research area is alstofolinine A total synthesis furan oxidation aza Achmatowicz rearrangement; oxidation rearrangement nucleophilic cyclization cascade azabicyclononane core preparation; aza-Achmatowicz rearrangement; furan; indole; natural-product synthesis; selective oxidation.

A reaction cascade of aza-Achmatowicz rearrangement followed by indole nucleophilic cyclization was developed to generate the common indole-fused azabicyclo[3.3.1]nonane core of the macroline family of alkaloids. The key to the success of the strategy relies on the careful manipulation of protecting groups and judicious selection of chemoselective furan oxidation conditions. The synthetic utility was further demonstrated on the asym. total synthesis of (-)-alstofolinine A (I). The compounds were evaluated for their antitumor activity using four cancer cell lines. Differential activities were observed, indicating that indole-containing multicyclic structures can exert potential and selective biomedical properties, justifying them as hit compounds worthy of further development.

Angewandte Chemie, International Edition published new progress about Achmatowicz reaction (aza-). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Safety of (S)-2-Methylpropane-2-sulfinamide.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Zhang, Ye published the artcileTotal Synthesis of (-)-Alstofolinine A: Selected Furan Oxidation/ Cyclization Cascade, Product Details of C4H11NOS, the main research area is chemoselective oxidation aza Achmatowicz rearrangement cyclization cascade diastereoselective; alstofolinine A total synthesis.

Indole-fused tetracyclic ring systems containing nitrogen atoms are common core skeletons of many indole alkaloids such as sarpagine, macroline, and ajmaline. Efficient and stereoselective construction of these ring systems can promote the development of the corresponding alkaloid syntheses. In this article, we briefly summarize our current progress toward the application of the aza-Achmatowicz reaction and indole nucleophilic addition reaction cascade for the first asym. total synthesis of the macroline-type indole alkaloid (-)-Alstofolinine A. Our synthetic strategy is based on furan oxidation/rearrangement and proceeds from easily accessible materials such as indole and furan derivatives

Synlett published new progress about Achmatowicz reaction (aza-). 343338-28-3 belongs to class amides-buliding-blocks, name is (S)-2-Methylpropane-2-sulfinamide, and the molecular formula is C4H11NOS, Product Details of C4H11NOS.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hornink, Milene M. published the artcileUltrasound-mediated radical cascade reactions: fast synthesis of functionalized indolines from 2-(((N-aryl)amino)methyl)acrylates, Quality Control of 123-39-7, the main research area is indoline acetamide methoxycarbonyl preparation green chem; acrylate arylaminomethyl ultrasound radical tandem addition cyclization formamide; Functionalized indolines; Indolines; Organic synthesis; Pulsed ultrasound; Sono-Fenton; Ultrasound.

Novel functionalized indolines were synthesized from 2-(((N-aryl)amino)methyl)acrylates and formamides under ultrasonic irradiation for the first time. Aiming to develop a straightforward and easy-to-implement methodol. for the synthesis of indolines, an instrumentation setup was designed, including ultrasound (US) equipment (Ultrasonic Horn; tip diameter of 12.7 mm, 20 kHz, maximum power of 400 W), an open reaction flask, and an inexpensive and green catalyst (1 mol%; FeSO4·7H2O) without the need for anhydrous conditions. The use of the sono-Fenton process in the presence of formamides and 2-(((N-aryl)amino)methyl)acrylates afforded a broad range of functionalized indolines within 60 s in high yields. Several exptl. parameters of the ultrasound-assisted reaction were evaluated, such as amplitude (40-80%), sonication time (15-60 s), and pulsed ultrasonic irradiation A 60 s silent reaction did not produce the desired indoline. The optimized conditions for US-mediated reactions allowed the production of functionalized indolines in high isolated yields (up to 99%, 60 s reaction time, pulse ratio 1 s:1 s, US amplitude 60%).

Ultrasonics Sonochemistry published new progress about Addition reaction catalysts. 123-39-7 belongs to class amides-buliding-blocks, name is N-Methylformamide, and the molecular formula is C2H5NO, Quality Control of 123-39-7.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics