Tag: 100-200

Kumar, Vishal; Dhawan, Sanjeev; Bala, Renu; Mohite, Sachin Balaso; Singh, Parvesh; Karpoormath, Rajshekhar published an article in 2022, the title of the article was Cu-catalysed transamidation of unactivated aliphatic amides.Quality Control of N,N-Diethylacetamide And the article contains the following content:

Direct transamidation was gaining prominence as a ground-breaking technique that generates a wide variety of amides without the requirement of acid-amine coupling or other intermediate steps. However, transamidation of unactivated aliphatic amides, on the other hand, was a long-standing issue in comparison to transamidation of activated amides. Herein, a transamidation approach of an unactivated aliphatic amide using a copper catalyst and chlorotrimethylsilane as an additive was reprted. In addition, used transamidation as a tool for selective N-C(O) cleavage and O-C(O) formation to synthesize 2-substituted benzoxazoles and benzothiazoles. The reactions were carried out without using any solvents and offered wide substitution scope. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Quality Control of N,N-Diethylacetamide

The Article related to amino phenyl alkylamide copper catalyst tranamidation, phenyl amide preparation, General Organic Chemistry: Synthetic Methods and other aspects.Quality Control of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Peng; Wang, Xiuhua; Ma, Yu; Sun, Yaxin; Zhang, Li; Yue, Jieyu; Fu, Kaiyue; Zhou, Jianrong Steve; Tang, Bo published an article in 2020, the title of the article was Nickel-catalyzed C-alkylation of thioamides, amides and esters by primary alcohols through a hydrogen autotransfer strategy.Product Details of 685-91-6 And the article contains the following content:

A simple catalyst of Ni(OAc)2 and P(t-Bu)3 enables selective C-alkylation of thioacetamides and primary acetamides with alcs. for the first time. Monoalkylation of thioamides, amides and t-Bu esters occurs in excellent yields (>95%). Mechanistic studies reveal that the reaction proceeds via a hydrogen autotransfer pathway. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Product Details of 685-91-6

The Article related to thioamide amide ester alkylation primary alc nickel catalyst chemoselective, General Organic Chemistry: Synthetic Methods and other aspects.Product Details of 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 3, 2017, Gu, Guoxian; Yang, Tilong; Yu, Ouran; Qian, Hua; Wang, Jiang; Wen, Jialin; Dang, Li; Zhang, Xumu published an article.Application of 65645-88-7 The title of the article was Enantioselective Iridium-Catalyzed Hydrogenation of 伪-Keto Amides to 伪-Hydroxy Amides. And the article contained the following:

A highly enantioselective iridium-catalyzed hydrogenation of 伪-keto amides to form 伪-hydroxy amides has been achieved with excellent results (up to >99% conversion and up to >99% ee, TON up to 100 000). As an example, this protocol was applied to the synthesis of (S)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol, the enantiomer of norepinephrine, which is widely used as an injectable drug for the treatment of critically low blood pressure. D. functional theory (DFT) calculations were also carried out to reveal the reaction mechanism. The experimental process involved the reaction of (S)-2-Hydroxy-N-methyl-2-phenylacetamide(cas: 65645-88-7).Application of 65645-88-7

The Article related to enantioselective iridium catalyzed hydrogenation keto amide hydroxy amide, General Organic Chemistry: Synthetic Methods and other aspects.Application of 65645-88-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Kiraly, Peter; Dal Poggetto, Guilherme; Castanar, Laura; Nilsson, Mathias; Deak, Andrea; Morris, Gareth A. published an article in 2021, the title of the article was Broadband measurement of true transverse relaxation rates in systems with coupled protons: application to the study of conformational exchange.Electric Literature of 685-91-6 And the article contains the following content:

Accurate measurement of transverse relaxation rates in coupled spin systems is important in the study of mol. dynamics, but is severely complicated by the signal modulations caused by scalar couplings in spin echo experiments The most widely used experiments for measuring transverse relaxation in coupled systems, CPMG and PROJECT, can suppress such modulations, but they also both suppress some relaxation contributions, and average relaxation rates between coupled spins. Here we introduce a new experiment which for the first time allows accurate broadband measurement of transverse relaxation rates of coupled protons, and hence the determination of exchange rate constants in slow exchange from relaxation measurements. The problems encountered with existing methods are illustrated, and the use of the new method is demonstrated for the classic case of hindered amide rotation and for the more challenging problem of exchange between helical enantiomers of a gold(I) complex. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Electric Literature of 685-91-6

The Article related to transverse relaxation rate conformational exchange, General Physical Chemistry: General Theories and other aspects.Electric Literature of 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 5, 2021, Das, Saikat; Murugesan, Kathiravan; Villegas Rodriguez, Gonzalo J.; Kaur, Jaspreet; Barham, Joshua P.; Savateev, Aleksandr; Antonietti, Markus; Koenig, Burkhard published an article.HPLC of Formula: 685-91-6 The title of the article was Photocatalytic (Het)arylation of C(sp3)-H Bonds with Carbon Nitride. And the article contained the following:

Mesoporous graphitic carbon nitride(mpg-CN)as a heterogeneous organic semiconductor photocatalyst for direct arylation of sp3 C-H bonds in combination with nickel catalysis are reported. This protocol has a broad synthetic scope (>70 examples including late-stage functionalization of drugs and agrochems.), was operationally simple, and shows high chemo- and regioselectivities. Facile separation and recycling of the mpg-CN catalyst in combination with its low preparation cost, innate photochem. stability, and low toxicity are beneficial features overcoming typical shortcomings of homogeneous photocatalysis. Detailed mechanistic investigations and kinetic studies indicate that an unprecedented energy-transfer process (EnT) from the organic semiconductor to the nickel complex was operated. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).HPLC of Formula: 685-91-6

The Article related to alkylamide aryl halide carbon nitride regioselective chemoselective arylation photochem, aryl methylalkylamide preparation, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Bonciolini, Stefano; Di Filippo, Mara; Baumann, Marcus published an article in 2020, the title of the article was A scalable continuous photochemical process for the generation of aminopropylsulfones.Category: amides-buliding-blocks And the article contains the following content:

An efficient continuous photochem. process that delivers a series of novel 纬-aminopropylsulfones RSO2CH2CH2CH(R1)N(R2)C(O)R3 (R = Ph, Et; R1 = H, Me; R2 = Me, Et; R3 = H, Ph, cyclohexyl, etc.) and RSO2CH2CH2CH(O)NHMe via a tetrabutylammonium decatungstate (TBADT) catalyzed HAT-process is presented. Crucial to this success is the exploitation of a new high-power LED emitting at 365 nm that was found to be superior to an alternative medium-pressure Hg lamp. The resulting flow process enabled the scale-up of this transformation reaching throughputs of 20 mmol h-1 at substrate concentrations up to 500 mM. Addnl., the substrate scope of this transformation was evaluated demonstrating the straightforward incorporation of different amine substituents as well as alkyl appendages next to the sulfone moiety. It is anticipated that this methodol. will allow for further exploitations of these underrepresented 纬-aminopropylsulfone scaffolds in the future. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Category: amides-buliding-blocks

The Article related to aminopropylsulfone preparation, amide vinyl sulfone coupling reaction tetrabutylammonium decatungstate photocatalyst, General Organic Chemistry: Synthetic Methods and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On April 16, 2021, Luo, Zhongli; Imamura, Kenji; Shiota, Yoshihito; Yoshizawa, Kazunari; Hisaeda, Yoshio; Shimakoshi, Hisashi published an article.Computed Properties of 685-91-6 The title of the article was One-Pot Synthesis of Tertiary Amides from Organic Trichlorides through Oxygen Atom Incorporation from Air by Convergent Paired Electrolysis. And the article contained the following:

A convergent paired electrolysis catalyzed by a B12 complex for the one-pot synthesis of a tertiary amide from organic trichlorides has been developed. Various readily available organic trichlorides, such as benzotrichloride and its derivatives, chloroform, dichlorodiphenyltrichloroethane (DDT), trichloro-2,2,2-trifluoroethane (CFC-113a), and trichloroacetonitrile (CNCCl3), were converted to amides in the presence of tertiary amines through oxygen incorporation from air at room temperature The amide formation mechanism in the paired electrolysis, which was mediated by a cobalt complex, was proposed. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Computed Properties of 685-91-6

The Article related to tertiary amide one pot synthesis chemoselective, organic trichloride tertiary amine paired electrolysis air, General Organic Chemistry: Synthetic Methods and other aspects.Computed Properties of 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 30, 2021, Han, Bo; Zhang, Jiong; Jiao, Haijun; Wu, Lipeng published an article.SDS of cas: 685-91-6 The title of the article was Zirconium-hydride-catalyzed site-selective hydroboration of amides for the synthesis of amines: Mechanism, scope, and application. And the article contained the following:

The selective hydroboration of primary, secondary, and tertiary amides at room temperature catalyzed by an earth-abundant-metal catalyst, Zr-H, for accessing diverse amines was reported. Various readily reducible functional groups, such as esters, alkynes, and alkenes, were well tolerated. Furthermore, the methodol. was extended to the synthesis of bio- and drug-derived amines. Detailed mechanistic studies revealed a reaction pathway entailing aldehyde and amido complex formation via an unusual C-N bond cleavage-reformation process, followed by C-O bond cleavage. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).SDS of cas: 685-91-6

The Article related to amide zirconium hydride catalyst regioselective hydroboration, amine preparation reaction mechanism, General Organic Chemistry: Synthetic Methods and other aspects.SDS of cas: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Wenjing; Yin, Changzhen; Yang, Xiao; Liu, Hailong; Zheng, Xueli; Yuan, Maolin; Li, Ruixiang; Fu, Haiyan; Chen, Hua published an article in 2017, the title of the article was Cu(II)-Mediated keto C(sp3)-H bond 伪-acyloxylation of N,N-dialkylamides with aromatic carboxylic acids.Safety of N,N-Diethylacetamide And the article contains the following content:

The selective oxidative coupling of aromatic carboxylic acids with the C(sp3)-H bond adjacent to the keto group of alkylamides was developed by employing a low cost copper source. This provides an efficient approach for synthesis of O-benzoylglycolamides. The protocol displayed good functional group tolerance. A broad range of benzoic acids directly coupled with alkylamides to afford a variety of O-benzoylglycolamides in moderate to good yields. In addition, a reasonable radical mechanism was proposed based on EPR experiments The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).Safety of N,N-Diethylacetamide

The Article related to copper catalyst acyloxylation dialkylamide aromatic carboxylic acid, benzoylglycolamide preparation, General Organic Chemistry: Synthetic Methods and other aspects.Safety of N,N-Diethylacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Das, Suman; Karmakar, Himadri; Bhattacharjee, Jayeeta; Panda, Tarun K. published an article in 2019, the title of the article was Aluminium complex as an efficient catalyst for the chemo-selective reduction of amides to amines.HPLC of Formula: 685-91-6 And the article contains the following content:

An efficient protocol for the catalytic chemo-selective reduction of tert-amides RC(O)N(R1)R2 (R = Me, Ph, 4-cyanophenyl, etc.; R1 = Me, Et, Ph, etc.; R2 = Me, Et, i-Pr; R1R2 = -(CH2)4-) with pinacolborane (HBpin) to afford the corresponding amines RCH2N(+)H(R1)R2Cl(-) in high yields using aluminum complexes I (X = S, Se) as pre-catalysts at room temp was reported. The aluminum complexes were prepared from the reaction of II (X = S, Se) and trimethylaluminum in toluene. The solid-state structure of complex I (X = Se) is established. Tertiary amides with a wide array of electron-withdrawing and electron-donating functional groups were easily converted to the desired products through the selective cleavage of the amides’ C=O bond by aluminum hydride as an active species. A kinetic study of the catalytic reaction is also reported. The experimental process involved the reaction of N,N-Diethylacetamide(cas: 685-91-6).HPLC of Formula: 685-91-6

The Article related to amine tertiary preparation chemoselective, tertiary amide reduction aluminum complex catalyst, General Organic Chemistry: Synthetic Methods and other aspects.HPLC of Formula: 685-91-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics