Tag: 100-200

Qin, Xudong; Yang, Weiting; Yang, Yonghang; Gu, Dongxu; Guo, Dongyu; Pan, Qinhe published an article in Inorganic Chemistry. The title of the article was 《A zinc metal-organic framework for concurrent adsorption and detection of uranium》.Application of 64479-78-3 The author mentioned the following in the article:

Uranium is one of the principal raw materials in the nuclear industry, but if released into the natural environment, it also poses latent health risks to mankind. Therefore, there is an urgent need to develop a strategy that can concurrently detect and adsorb uranium to realize the sustainable development of nuclear power and protect the environment. In this work, a fluorescent zinc-based metal-organic framework (HNU-50) was designed and synthesized for the effective detection and extraction of U(VI). The amide groups on N-pyridin-4-ylpyridine-4-carboxamide ligands and two uncoordinated carboxyl oxygen atoms on pyromellitic acid ligands in HNU-50 provide potential uranium-binding sites. Consequently, HNU-50 is competent of selectively and efficiently catching uranyl ions, achieving an optimum adsorption capacity of 632 mg/g. Addnl., the adsorption of U(VI) results in fluorescence quenching of HNU-50, thus allowing sensitive and selective detection of U(VI) by fluorescence change. Note that HNU-50 exhibits a considerably low detection limit of 1.2 x 10-8 M for U(VI) in aqueous solution, which is below the World Health Organization maximum pollution standards for potable water (6.3 x 10-8 M). A zinc MOF was successfully constructed by the connection between Zn(II), NPYC, and PMA ligands, which can be used to concurrently detect and adsorb uranium in aqueous solution In addition to this study using N-(Pyridin-4-yl)isonicotinamide, there are many other studies that have used N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3Application of 64479-78-3) was used in this study.

N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3) belongs to amides.Application of 64479-78-3Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthetic Route of C10H14N2OOn November 8, 2004 ,《Synthesis of optically active ring-A substituted tryptophans as IDO inhibitors》 appeared in Tetrahedron Letters. The author of the article were Li, Xiaoyan; Yin, Wenyuan; Sarma, P. V. V. Srirama; Zhou, Hao; Ma, Jun; Cook, James M.. The article conveys some information:

The first stereoselective synthesis of optically active 6-chloro-L-tryptophan, 5-nitro-D-tryptophan, 6-nitro-D-tryptophan, 5,6-dichloro-L-tryptophan, 6-aza-D-tryptophan, as well as the first synthesis of the optically active 7-methoxy-D-tryptophan with potential activity at IDO (IDO = indoleamine 2,3-dioxygenase) via the Schollkopf chiral auxiliary is described. In addition to this study using 2,2-Dimehtyl-N-pyridin-3-yl-propionamide, there are many other studies that have used 2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3Synthetic Route of C10H14N2O) was used in this study.

2,2-Dimehtyl-N-pyridin-3-yl-propionamide(cas: 70298-88-3) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).Synthetic Route of C10H14N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

The author of 《Iodoamination of Alkenyl Sulfonamides by Potassium Iodide and Hydrogen Peroxide in Aqueous Medium》 were Giofre, Sabrina; Sala, Roberto; Beccalli, Egle Maria; Presti, Leonardo Lo; Broggini, Gianluigi. And the article was published in Helvetica Chimica Acta in 2019. Electric Literature of C7H9NO2S The author mentioned the following in the article:

A procedure for the iodoamination of unfunctionalized olefins tethered to a tosyl-protected NH-group has been developed. The combined use of KI and H2O2 in aqueous medium was effective for the preparation of iodomethyl-substituted nitrogen-containing heterocycles. The selective exo-trig iodocyclization provided 1,2-bifunctional 5-, 6-, and 7-membered cyclic skeletons. In the experiment, the researchers used many compounds, for example, 4-Methylbenzenesulfonamide(cas: 70-55-3Electric Literature of C7H9NO2S)

4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Electric Literature of C7H9NO2S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

In 2019,Organic Chemistry Frontiers included an article by Qi, Jifeng; Tang, Haibin; Chen, Changwei; Cui, Sunliang; Xu, Gang. Computed Properties of C7H9NO2S. The article was titled 《Reductive coupling of alkenes with unsaturated imines via a radical pathway》. The information in the text is summarized as follows:

The reductive coupling of unsaturated imines with alkenes via a radical pathway was reported. Various unsaturated imines and alkenes delivered structurally diversified benzofurans, benzothiophenes and medium-sized benzofuran-fused heterocycles. The protocol features mild reaction conditions and broad substrate scope. In addition to this study using 4-Methylbenzenesulfonamide, there are many other studies that have used 4-Methylbenzenesulfonamide(cas: 70-55-3Computed Properties of C7H9NO2S) was used in this study.

4-Methylbenzenesulfonamide(cas: 70-55-3) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Computed Properties of C7H9NO2S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

In 2018,Downey, C. Wade; Glist, Hadleigh M.; Takashima, Anna; Bottum, Samuel R.; Dixon, Grant J. published 《Chalcone and cinnamate synthesis via one-pot enol silane formation-Mukaiyama aldol reactions of ketones and acetate esters》.Tetrahedron Letters published the findings.Synthetic Route of C4H9NO2 The information in the text is summarized as follows:

Aryl alkyl ketones, acetate esters, and acetamides undergo facile one-pot enol silane formation, Mukaiyama aldol addition, and dehydrosilyloxylation in the presence of an amine base and excess trimethylsilyl trifluoromethanesulfonate. The chalcone and cinnamate products are generally recovered in high yield. The relative stoichiometry of the trimethylsilyl trifluoromethanesulfonate and amine base reagents determines whether the reaction yields the β-silyloxy carbonyl product or the α,β-unsaturated carbonyl. The experimental part of the paper was very detailed, including the reaction process of N-Methoxy-N-methylacetamide(cas: 78191-00-1Synthetic Route of C4H9NO2)

N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Synthetic Route of C4H9NO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

In 2017,Yoneda, Naoki; Fujii, Yuki; Matsumoto, Akira; Asano, Keisuke; Matsubara, Seijiro published 《Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins》.Nature Communications published the findings.Recommanded Product: 78191-00-1 The information in the text is summarized as follows:

A concise organocatalytic cycloetherification for the highly enantio- and diastereoselective synthesis of tetrahydropyrans involving simultaneous construction of two chiral centers, one of which is fully substituted was presented. This method involved dynamic kinetic resolution of reversibly generated chiral cyanohydrins. A chiral bifunctional organocatalyst selectively recognizes a specific chair-like conformation of the intermediate, in which the small steric effect of the linear cyano group as well as its anomeric effect play important roles in controlling stereoselectivity. The products offer addnl. utility as synthetic intermediates because the cyano group can be further transformed into a variety of important functional groups. This strategy provides a platform to design efficient approaches to obtain a wide range of optically active tetrahydropyrans, which are otherwise synthetically challenging materials. In the part of experimental materials, we found many familiar compounds, such as N-Methoxy-N-methylacetamide(cas: 78191-00-1Recommanded Product: 78191-00-1)

N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Nitrous acid converts secondary amines (aliphatic or aromatic) to N-nitroso compounds (nitrosamines): R2NH + HNO2 → R2N―NO. Some nitrosamines are potent cancer-inducing substances, and their possible formation is a serious consideration when nitrites, which are salts of nitrous acid, are present in foods or pharmaceutical preparations. Tertiary amines give rise to nitrosamines more slowly; an alkyl group is eliminated as an aldehyde or ketone, along with nitrous oxide, N2O.Recommanded Product: 78191-00-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

In 2016,Eshtiyaghi, Mahbobeh; Deldar, Hamid; Pirsaraei, Zarbakht Ansari; Shohreh, Bahram published 《Royal jelly may improve the metabolism of glucose and redox state of ovine oocytes matured in vitro and embryonic development following in vitro fertilization》.Theriogenology published the findings.Synthetic Route of C4H9NO2 The information in the text is summarized as follows:

The aim of this study was to investigate the effect of different concentrations of royal jelly (RJ) on in vitro maturation (IVM), fertilization, cleavage, blastocyst rates, glutathione (GSH) content in ovine oocyte, mRNA abundance of antioxidant enzymes in both oocyte and cumulus, and glucose metabolism-related genes in cumulus cells. In vitro maturation of oocyte was performed in the presence of control (RJ0), 2.5 (RJ2.5), 5 (RJ5), and 10 (RJ10) mg/mL of RJ. Nuclear status, intracellular GSH content in oocytes, and mRNA abundance of selected genes were evaluated following 24 h of IVM. Following the IVM, fertilization and embryo culture were carried out in all the groups and embryonic development was examined The addition of 10-mg/mL RJ to maturation media not only yielded a higher number of oocytes at MII stage but also showed an increased level of intracellular GSH content than did RJ2.5 and control groups. Fertilization, cleavage, and blastocyst rate were higher in the RJ10 treatment group in comparison to the control one. In cumulus cells, the expression of PFKM, PFKL, and G6PDH were increased following the addition of RJ to the maturation media. Supplementation of 10-mg/mL RJ to IVM medium increased the GPx mRNA abundance in both oocyte and cumulus cells and SOD expression in the cumulus cells. The CAT mRNA abundance was not influenced by the addition of RJ to the maturation media in either oocyte or cumulus cells. It seems that the improvement of oocyte maturation and its subsequent development in RJ10 group may be associated with amelioration of redox status in the oocytes and activation of glucose metabolic pathways in their surrounding cumulus cells. The experimental process involved the reaction of N-Methoxy-N-methylacetamide(cas: 78191-00-1Synthetic Route of C4H9NO2)

N-Methoxy-N-methylacetamide(cas: 78191-00-1) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Synthetic Route of C4H9NO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Application In Synthesis of N-(Pyridin-4-yl)isonicotinamideOn September 2, 2014 ,《Targeted Structure Modulation of “”Pillar-Layered”” Metal-Organic Frameworks for CO2 Capture》 was published in Inorganic Chemistry. The article was written by Xuan, Zhi-Hong; Zhang, Da-Shuai; Chang, Ze; Hu, Tong-Liang; Bu, Xian-He. The article contains the following contents:

Two new zinc MOFs with similar “”pillar-layered”” framework structures based on 1,1′-biphenyl-2,2′,6,6′-tetracarboxylic acid (H4bpta) and two different bipyridine pillar ligands, namely {[Zn4(bpta)2(4-pna)2(H2O)2]·4DMF·3H2O}n (1) and {[Zn2(bpta)(bpy-ea)(H2O)]·2DMF·H2O}n (2) (4-pna = N-(4-pyridyl)isonicotinamide and bpy-ea = 1,2-bis(4-pyridyl)ethane), were synthesized and studied with their CO2 adsorption properties. By anal. of the structure properties and the CO2 adsorption performances of these two MOFs, the introduction of polar acylamide groups via 4-pna resulted in 1 with enhanced CO2 capacity and CO2/CH4 selectivity at low pressure. In contrast, the framework of 2 shows flexible properties originating from the flexibility of the ethanediylidene group in the bpy-ea ligand, which benefits the sieve effect of pores to give higher CO2/CH4 selectivity at a relatively high pressure range. The results came from multiple reactions, including the reaction of N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3Application In Synthesis of N-(Pyridin-4-yl)isonicotinamide)

N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds.Application In Synthesis of N-(Pyridin-4-yl)isonicotinamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Quality Control of N-(Pyridin-4-yl)isonicotinamideOn September 30, 1999 ,《New coordination networks constructed from N-(4-pyridyl)isonicotinamide》 was published in Crystal Engineering. The article was written by Kondo, Mitsuru; Asami, Akiko; Chang, Ho-Chol; Kitagawa, Susumu. The article contains the following contents:

New coordination polymers of N-(4-pyridyl)isonicotinamide (pia) were prepared and crystallog. characterized. Compound 1, [Cd(pia)(NCS)2]n, provides a rectangular, two-dimensional network, which is constructed by a single bridging of the pia ligand and double bridging of the NCS ligands. Compound 2, [Cu(pzdc)(pia)2]n (pzdc = pyrazine-2,3-dicarboxylate), forms a fishbone-type, 1-dimensional network, which is comprised of -(Cu-pzdc)- chains with pia ligands. The imino-pyridine donor of the pia binds to the chains, in which the other remains free. The π-π and hydrogen bonding interactions between the pia ligands in the adjacent chains provide a three-dimensional structure. In the part of experimental materials, we found many familiar compounds, such as N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3Quality Control of N-(Pyridin-4-yl)isonicotinamide)

N-(Pyridin-4-yl)isonicotinamide(cas: 64479-78-3) belongs to amides.Quality Control of N-(Pyridin-4-yl)isonicotinamideAmides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis.

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

《Surface-Active Ionic-Liquid-Encapsulated Polyoxometalate Nanospheres: Construction, Self-Assembly, Adsorption Behavior, and Application for Dye Removal》 was written by Qi, Lubin; Gong, Yanjun; Fang, Ming; Jia, Zhiwei; Cheng, Ni; Yu, Li. Quality Control of 2-Bromoacetamide And the article was included in ACS Applied Nano Materials in 2020. The article conveys some information:

Preparation of materials which efficiently adsorb environmental pollutants, e.g., non-biodegradable dyes, is urgently demanded. Preparation, characterization, and use of surface-active, ionic liquid-encapsulated polyoxometalates (SAILEP) are reported. These ordered structured hybrid materials were prepared in the aqueous phase by one-pot self-assembly at room temperature They demonstrated a high capacity for rapid cationic dye adsorption. Rhodamine B (RhB) adsorption equilibrium time was only 1 min. These SAILEP materials can also selectively sep. RhB from an eosin Y/RhB mixture Fast, selective adsorption was attributed to electrostatic interactions and high affinity between SAILEP and RhB. An assessment of adsorption isotherms and kinetics indicated dye adsorption followed Langmuir isotherm models and pseudo-second-order kinetics. Self-assembly was assessed by small-angle x-ray scattering, Fourier transform IR, and dynamic light scattering. Results provide addnl. insight on SAILEP hybrid materials, which have great potential for dye decontamination. In the experiment, the researchers used 2-Bromoacetamide(cas: 683-57-8Quality Control of 2-Bromoacetamide)

2-Bromoacetamide(cas: 683-57-8) can be used in preparation of (2-carbamoylmethoxy-5-chloro-benzyl)-carbamic acid tert-butyl ester. It was aslo used as precursor to dehydropeptidase I inactivator.Quality Control of 2-Bromoacetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics