Tag: 200-300

A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines was written by Beutner, Gregory L.;Kuethe, Jeffrey T.;Yasuda, Nobuyoshi. And the article was included in Tetrahedron Letters in 2009.Related Products of 116332-61-7 This article mentions the following:

In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups at the 3-position. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Related Products of 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Related Products of 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sodium perborate bleaching of cotton by using tetraacetyl ethylenediamine activator was written by Indi, Yashovardhan Mallikarjun;Wasif, Akhilahmad. And the article was included in Indian Journal of Fibre & Textile Research in 2018.Recommanded Product: 10543-57-4 This article mentions the following:

In the present work, attempt has been made to bleach the scoured cotton fabric with sodium perborate as bleaching agent and tetraacetyl ethylenediamine as bleach activator. The concentrations of these chems., temperature and time of the treatment have been varied. When sodium perborate comes in contact with water in bleaching bath, it releases hydrogen peroxide which is responsible for bleaching action on cotton. The findings of this novel process on the quality of bleached fabric are compared with the fabric bleached conventionally using only hydrogen peroxide. The results show that the utilization of generated hydrogen peroxide reaches as high as 96% in the modified bleaching process, which is only 70% in the case of conventional bleaching. Further, the modified bleaching process requires less water and energy, thus fulfilling the requirements of ecofriendly process. Loss in weight, tearing strength and tensile strength are found less comparing to conventional bleaching without compromising with whiteness index. CIE whiteness with conventional bleaching is 57, whereas modified recipe shows 61 whiteness. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Recommanded Product: 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Recommanded Product: 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Rhodium(III)-catalyzed Oxidative Coupling of N-Methoxybenzamides and Ethenesulfonyl fluoride: a C-H Bond Activation Strategy for the Preparation of 2-Aryl ethenesulfonyl fluorides and Sulfonyl fluoride Substituted γ-Lactams was written by Wang, Shi-Meng;Li, Chen;Leng, Jing;Bukhari, Syed Nasir Abbas;Qin, Hua-Li. And the article was included in Organic Chemistry Frontiers in 2018.SDS of cas: 192436-83-2 This article mentions the following:

A method for the synthesis of 2-aryl ethenesulfonyl fluorides such as I [R = 4-Me, 4-OMe, 5-Ph, etc.] and sulfonyl fluoride substituted γ-lactams II [R = 4-Me, 4-OMe, 6-Ph, etc.] was developed through a rhodium(III)-catalyzed oxidative coupling of N-methoxybenzamides and ethenesulfonyl fluoride in moderate to excellent yields. This protocol featured an exclusive E-stereo selectivity and a monoselective ortho activation of sp² C-H bonds of the benzene rings. This research revealed that the much less reactive Heck coupling partner ethenesulfonyl fluoride possesses the feasibility for coupling with sp² C-H bonds to provide a class of new sulfonyl fluoride scaffolds for the SuFEx click reaction. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2SDS of cas: 192436-83-2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.SDS of cas: 192436-83-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ionic liquids/ZnO nanoparticles as recyclable catalyst for polycarbonate depolymerization was written by Iannone, Francesco;Casiello, Michele;Monopoli, Antonio;Cotugno, Pietro;Sportelli, Maria Chiara;Picca, Rosaria Anna;Cioffi, Nicola;Dell’Anna, Maria M.;Nacci, Angelo. And the article was included in Journal of Molecular Catalysis A: Chemical in 2017.Computed Properties of C13H24N2O This article mentions the following:

A useful protocol for waste bis-phenol A-polycarbonates (BPA-PC) chem. recycling is proposed based on a bifunctional acid/basic catalyst composed by nanostructured zinc oxide and tetrabutylammonium chloride (ZnO-NPs/NBu₄Cl) in quality of Lewis acid and base, resp. Retro-polymerization reaction proved to be of general application for several nucleophiles, including water, alcs., amines, polyols, aminols and polyamines, leading to the complete recovery of BPA monomer and enabling the PC polymer to function as a green carbonylating agent (green phosgene alternative) for preparing carbonates, urethanes and ureas. A complete depolymerization can be obtained in seven hours at 100 °C and ZnO nanocatalyst can be recycled several times without sensible loss of activity. Remarkably, when polycarbonate is reacted with glycerol, it is possible to realize in a single process the conversion of two industrial wastes (BPA-PC and glycerol) into two valuable chems. like BPA monomer and glycerol carbonate (the latter being a useful industrial solvent and fuel additive). In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Computed Properties of C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Computed Properties of C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Direct coupling of sp³ carbon of alkanes with α,β-unsaturated carbonyl compounds using a copper/hydroperoxide system was written by Lan, Yun;Yang, Chao;Xu, Yun-He;Loh, Teck-Peng. And the article was included in Organic Chemistry Frontiers in 2017.Product Details of 116332-61-7 This article mentions the following:

A new methodol. for the monovalent copper-initiated direct coupling of alkanes and hydroperoxides with unsaturated carbonyl compounds was developed. In this work, α,β-unsaturated carbonyl compounds underwent alkylation and peroxidation to give synthetically useful α-peroxy ketones with wide functional group tolerance. The resulting α-peroxy ketones could be easily transformed into very useful α-hydroxy ketones. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Product Details of 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Product Details of 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis and characterization of dicyclohexylurea by the improved green methodology was written by Saurabh, Pandey;Pal, Lamba Narendra;Singh, Chauhan Manmohan;Arkaja, Goswami. And the article was included in Research Journal of Chemistry and Environment in 2022.Product Details of 2387-23-7 This article mentions the following:

The reaction of cyclohexylamine with urea under solvent-free condition is discussed. The one-step and one-pot synthesis via transamination for industrial production is studied where, cyclohexylamine is heated with urea to give desired product dicyclohexylurea (DCU) in molar yield. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Product Details of 2387-23-7).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Product Details of 2387-23-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles was written by Desaintjean, Alexandre;Haupt, Tobias;Bole, Leonie J.;Judge, Neil R.;Hevia, Eva;Knochel, Paul. And the article was included in Angewandte Chemie, International Edition in 2021.COA of Formula: C10H10F3NO2 This article mentions the following:

Using the bimetallic combination sBu₂Mg·2 LiOR (R = 2-ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo-arenes and -heteroarenes under mild reaction conditions and provides bromo-substituted magnesium reagents. Assessing the role of Lewis donor additives in these reactions revealed that N,N,N’,N”,N”-pentamethyldiethylenetriamine (PMDTA) finely tunes the regioselectivity of the Br/Mg exchange on dibromo-pyridines and quinolines. Combining spectroscopic with X-ray crystallog. studies, light has been shed on the mixed Li/Mg constitution of the organometallic intermediates accomplishing these transformations. These systems reacted effectively with a broad range of electrophiles, including allyl bromides, ketones, aldehydes, and Weinreb amides in good yields. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7COA of Formula: C10H10F3NO2).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.COA of Formula: C10H10F3NO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Amine-Responsive Disassembly of Au^I-Cu^I Double Salts for Oxidative Carbonylation was written by Cao, Yanwei;Yang, Jian-Gong;Deng, Yi;Wang, Shengchun;Liu, Qi;Shen, Chaoren;Lu, Wei;Che, Chi-Ming;Chen, Yong;He, Lin. And the article was included in Angewandte Chemie, International Edition in 2020.Application In Synthesis of 1,3-Dicyclohexylurea This article mentions the following:

A sensitive amine-responsive disassembly of self-assembled Au^I-Cu^I double salts was observed and its use for the synergistic catalysis was enlightened. Study of the disassembly of [Au(NHC)₂][CuI₂] revealed the contribution of Cu-assisted ligand exchange of N-heterocyclic carbene (NHC) by amine in [Au(NHC)₂]⁺ and the capacity of [CuI₂]^– on the oxidative step. By integrating the implicative information coded in the responsive behavior and inherent catalytic functions of d¹⁰ metal complexes, a catalyst for the oxidative carbonylation of amines was developed. The advantages of this method were clearly reflected on mild reaction conditions and the significantly expanded scope (51 examples); both primary and steric secondary amines can be employed as substrates. The cooperative reactivity from Au and Cu centers, as an indispensable prerequisite for the excellent catalytic performance, was validated in the synthesis of (un)sym. ureas and carbamates. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Application In Synthesis of 1,3-Dicyclohexylurea).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Application In Synthesis of 1,3-Dicyclohexylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Organic ligand and solvent free oxidative carbonylation of amine over Pd/TiO₂ with unprecedented activity was written by Liu, Shujuan;Dai, Xingchao;Wang, Hongli;Shi, Feng. And the article was included in Green Chemistry in 2019.Recommanded Product: 2387-23-7 This article mentions the following:

A highly active Pd/TiO₂ catalyst system was prepared and applied in the oxidative carbonylation of amines to ureas with ultra-low Pd content under organic ligand and solvent free conditions. The catalytic turnover frequencies (TOFs, moles of amines converted per mol of Pd per h) were 126 000 and 250 000 h^-1 for the production of diphenylurea and dibenzylurea, resp. An expanded substrate scope including the electron-rich and electron-deficient anilines, primary aliphatic amines, secondary amines was also established. This work offers a straightforward, step economic, and green methodol. for the efficient synthesis of valuable ureas. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Recommanded Product: 2387-23-7).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Recommanded Product: 2387-23-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Activated low temperature bleaching of cotton fabric with glucose oxidase was written by Zhao, Zheng;Chen, Ting-Chun;Zhu, Quan;Zhu, Li-Min. And the article was included in Yinran in 2011.Related Products of 10543-57-4 This article mentions the following:

In low-temperature bleaching of cotton fabric with glucose oxidase, the decomposition of H₂O₂ is only about 50%, so activator TAED is introduced into the bleaching system. The optimal process of activated low-temperature bleaching is: pH value 7.0, n(TAED):n(H₂O₂) 0.5:1, bleaching at 70 °C for 60 min, bath ratio 10:1, and sodium pyrophosphate 2g/L. Decomposition rate of H₂O₂ is above 98% in the activated low temperature bleaching system. The whiteness of the fabric bleached in the activated low temperature process is lower than that in the traditional process. Compared with traditional bleaching process, low temperature bleaching with glucose oxidase has lower damage and less strength loss to fibers. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Related Products of 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Related Products of 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics