Tag: 200-300

Complete enzymatic pre-treatment of cotton fabric with incorporated bleach activator was written by Spicka, Nina;Tavcer, Petra Forte. And the article was included in Textile Research Journal in 2013.Category: amides-buliding-blocks This article mentions the following:

The feasibility of a complete enzymic one-bath pre-treatment of the cotton fabric at low temperature was investigated in this study. The cotton fabric was enzymically desized, scoured and bleached with an enzyme mixture of starch-degrading enzymes, pectinases and glucose oxidases, resp. Starch-degrading enzymes hydrolyzed the sizing agent into glucose. Glucose oxidases catalyzed the oxidation of β-D-glucose to D-glucono-ω-lactone and simultaneously generated hydrogen peroxide. The desizing and hydrogen peroxide generation each took one hour. For bleaching, hydrogen peroxide was converted into peracetic acid by incorporating the bleach activator tetraacetylethylenediamine (TAED). Bleaching took place at 50°C and neutral pH, where peracetic acid is most effective. Pectinases were added into the pre-treatment bath to remove pectins from fibers and improve their wettability. Whiteness values, water absorbency, polymerization degree and tenacity at maximum load were measured on pre-treated samples. The total organic carbon, pH and biodegradability were measured on residual pre-treatment baths. It was established that hydrogen peroxide can be efficiently enzymically produced from the sizing agent and converted with TAED to form peracetic acid to bleach the cotton fabric. Cotton fabrics with a medium degree of whiteness, W = 51, and good water absorbency can be obtained at low water and energy consumption. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Category: amides-buliding-blocks).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Efficient and general one-pot synthesis of β-chloro-β-trifluoromethylated enones from 3,3,3-trifluoropropyne was written by Jeon, Sung Lan;Kim, Dae Ho;Son, Jang Bae;Jeong, In Howa. And the article was included in Bulletin of the Korean Chemical Society in 2006.Safety of 4-Bromo-N-methoxy-N-methylbenzamide This article mentions the following:

CF₃CCH reacted with Weinreb amides in BuLi/THF to give CF₃CCl:CHCOR [R = (un)substituted Ph, 1-naphthalenyl, 2-furanyl, cyclohexyl] as E-Z mixtures In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Safety of 4-Bromo-N-methoxy-N-methylbenzamide).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Safety of 4-Bromo-N-methoxy-N-methylbenzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis and in vitro biological evaluation of pyrazole group-containing analogues for PDE10A was written by Li, Junfeng;Jin, Hongjun;Zhou, Haiying;Rothfuss, Justin;Tu, Zhude. And the article was included in MedChemComm in 2013.Computed Properties of C9H10BrNO2 This article mentions the following:

Twenty eight new analogs were synthesized by optimizing the structure of MP-10 and their in vitro binding affinities towards PDE10 Å, PDE3A/B, and PDE4A/B were determined Among these new analogs are very potent towards PDE10 Å and have IC₅₀ values of 0.40 ± 0.02, 0.28 ± 0.06, 1.82 ± 0.25, 0.24 ± 0.05, 0.36 ± 0.03 and 1.78 ± 0.03 nM, resp.; these six compounds displayed high selectivity for PDE10 Å vs. PDE3A/3B/4A/4B. The promising compounds will be further validated in vivo to identify PDE10 Å imaging tracers. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Computed Properties of C9H10BrNO2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Computed Properties of C9H10BrNO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hydrosilane-Assisted Synthesis of Urea Derivatives from CO₂ and Amines was written by Zhao, Yulei;Guo, Xuqiang;Si, Zhiyao;Hu, Yanan;Sun, Ying;Liu, Yunlin;Ji, Zhongyin;You, Jinmao. And the article was included in Journal of Organic Chemistry in 2020.Quality Control of 1,3-Dicyclohexylurea This article mentions the following:

A methodol. employing CO₂, amines, and phenylsilane was discussed to access aryl- or alkyl-substituted urea derivatives This procedure was characterized by adopting hydrosilane to promote the formation of ureas directly, without the need to prepare silylamines in advance. Control reactions suggested that FeCl₃ was a favorable additive for the generation of ureas, and this 1,5,7-triazabicyclo[4.4.0]dec-5-ene-catalyzed reaction might proceed through nucleophilic addition, silicon migration, and the subsequent formal substitution of silylcarbamate. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Quality Control of 1,3-Dicyclohexylurea).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Quality Control of 1,3-Dicyclohexylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Direct Access to Aryl Bis(trifluoromethyl)carbinols from Aryl Bromides or Fluorosulfates: Palladium-Catalyzed Carbonylation was written by Domino, Katrine;Veryser, Cedrick;Wahlqvist, Benjamin A.;Gaardbo, Cecilie;Neumann, Karoline T.;Daasbjerg, Kim;De Borggraeve, Wim M.;Skrydstrup, Troels. And the article was included in Angewandte Chemie, International Edition in 2018.Category: amides-buliding-blocks This article mentions the following:

A palladium-catalyzed carbonylative approach for the direct conversion of (hetero)aryl bromides into their α,α-bis(trifluoromethyl)carbinols is described, and it employs only stoichiometric amounts of carbon monoxide and trifluoromethyltrimethylsilane. In addition, aryl fluorosulfates proved highly compatible with these reaction conditions. The method is tolerant of a diverse set of functional groups, and it is adaptable to late-stage carbon-isotope labeling. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Category: amides-buliding-blocks).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Source-related smart suspect screening in the aqueous environment: search for tire-derived persistent and mobile trace organic contaminants in surface waters was written by Seiwert, Bettina;Kloeckner, Philipp;Wagner, Stephan;Reemtsma, Thorsten. And the article was included in Analytical and Bioanalytical Chemistry in 2020.Synthetic Route of C13H24N2O This article mentions the following:

A variant of suspect screening by liquid chromatog.-high-resolution mass spectrometry (LC-HRMS) is proposed in this study: Samples of a potential source of contamination and of an environmental sample close to this source are first analyzed in a non-targeted manner to select source-related suspects and to identify them. The suspect list compiled from such an exercise is then applied to LC-HRMS data of environmental samples to ascribe and to identify persistent and mobile contaminants in the water cycle that may originate from the source under study. This approach was applied to tire crumb rubber (source) and road dust (close to source); by comparison of the two data sets, 88% of the features detected in tire leachate could be excluded. Of the 48 suspects remaining, a total of 41 could be tentatively identified as either related to hexamethoxymethyl melamine or cyclic amines, benzothiazoles, or glycols. Subsequently, environmental samples were searched for these suspects: 85% were determined in an urban creek after a combined sewer overflow and 67% in the influent of a municipal wastewater treatment plant (WWTP). These exceptionally high rates of pos. findings prove that this source-related smart suspect screening effectively directs the effort of selecting and identifying unknown contaminants to those related to the source of interest. The WWTP effluent and the urban creek during dry weather also showed the presence of numerous contaminants that may stem from tire and road wear particles (TRWP) in road runoff. Contribution from other sources, however, cannot be ruled out. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Synthetic Route of C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Synthetic Route of C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis and characterization of liquid molecular brush binder for coating applications was written by Phiri, Mapoloko Mpho;Hadasha, Waled;Pfukwa, Rueben;Klumperman, Bert. And the article was included in European Polymer Journal in 2018.Computed Properties of C13H24N2O This article mentions the following:

This report documents the facile synthesis of mol. brushes, via a grafting onto approach, with potential application as coating binders. Firstly, alternating copolymers of Bu vinyl ether (n-BVE) and maleic anhydride (MAh), i.e. n-BVEMAh, were synthesized via conventional radical polymerization The anhydride reactive handle was subsequently utilized to access mol. brushes, via a grafting onto method, by imidizing the MAh repeat units with amine end-functional poly(ethylene glycol) oligomers, with 12 repeating units (PEG₁₂-NH₂). The product n-BVEMI-PEG₁₂ brushes were viscous liquids at room temperature, hence we termed them liquid mol. brushes (LMBs). The LMBs displayed Newtonian flow behavior at shear rates below 1000 s^-1. We evaluated the applicability of this mol. brush system as coating binder, by grafting varying fractions of linoleamide (Lin) side chains, which has oxidative crosslinking ability, along with the PEG₁₂ onto n-BVEMAh, to access n-BVEMI-PEG₁₂/Lin. The n-BVEMI-PEG₁₂/Lin binders underwent oxidative crosslinking at 50 °C in the presence of a drier. The challenges associated with the current binder system are highlighted. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Computed Properties of C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Computed Properties of C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis of various acylating agents directly from carboxylic acids was written by Pilathottathil, Fathima;Vineet Kumar, Doppalapudi;Kaliyamoorthy, Alagiri. And the article was included in Synthetic Communications in 2020.Recommanded Product: 192436-83-2 This article mentions the following:

A straightforward synthesis of acylating reagents such as Weinreb and MAP amides from aromatic, aliphatic carboxylic acids, and amino acids using PPh₃/NBS combination was described. A chemoselective modification of the carboxylic acid group into Weinreb amide in the presence of more reactive aldehydes and ketones was presented. All reactions were performed at ambient temperature under air using undried com. grade solvent. Furthermore, the present methodol. could be performed at a gram scale under inert-free reaction conditions. In addition, 7-azaindoline amide auxiliary (used for catalytic asym. aldol- and Mannich-type reactions), which behaves like Weinreb amide is also synthesized under similar reaction conditions. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Recommanded Product: 192436-83-2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 192436-83-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Organophotocatalytic N-O Bond Cleavage of Weinreb Amides: Mechanism-Guided Evolution of a PET to ConPET Platform was written by Soika, Julia;McLaughlin, Calum;Nevesely, Tomas;Daniliuc, Constantin G.;Molloy, John. J.;Gilmour, Ryan. And the article was included in ACS Catalysis in 2022.Application of 116332-61-7 This article mentions the following:

Mechanistically guided reaction development demonstrates the involvement of a photoinduced electron transfer (PET) mechanism, and this has been further advanced to a consecutive photoinduced electron transfer (ConPET) manifold and this has significantly expanded the scope of compatible substrates RC(O)N(CH₃)OCH₃ (R = 4-cyanomethyl, pyrazin-2-yl, penta-1,3-dien-1-yl, etc.). In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Application of 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Application of 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Intramolecular ipso-arylative cyclization of aryl-alkynoates and N-arylpropiolamides with aryldiazonium salts through merged gold/visible light photoredox catalysis was written by Bansode, Avinash H.;Shaikh, Samir R.;Gonnade, Rajesh G.;Patil, Nitin T.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Quality Control of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide This article mentions the following:

A visible-light-promoted merged gold/photoredox catalyzed ipso-arylative cyclization has been reported. For instance, the reaction of aryl-alkynoates and N-arylpropiolamides with aryldiazonium salts in the presence of catalytic amounts of [(4-OCH₃)C₆H₄]₃PAuCl and Ru(bpy)₃(PF₆)₂ under irradiation using a 32 W CFL bulb gave arylated spirocarbocycles in moderate to good yields. In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6Quality Control of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide).

N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Quality Control of N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics