Tag: 200-300

Oxidation-reduction potentials of N-(arenesulfonyl)quinonimine-arenesulfonamidophenol systems was written by Dubina, V. L.;Burmistrov, K. S.. And the article was included in Zhurnal Organicheskoi Khimii in 1977.Name: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide This article mentions the following:

Oxidation-reduction potentials (EN) were determined for 11 N-(4-hydroxyphenyl)arenesulfonamides, 3 N-(4-hydroxy-1-naphthyl)benzenesulfonamides, and 5 N-(2-hydroxyphenyl)benzenesulfonamides in a (AcO)4Pb system. Residual (AcO)4Pb was titrated with 0.5M AcONa in glacial AcOH. The highest EN, 0.887 v for N-(4-chloro-2-hydroxyphenyl)benzenesulfonamide, was only 0.014 v higher than the EN for its 5-chloro isomer. In the experiment, the researchers used many compounds, for example, N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6Name: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide).

N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide (cas: 1146-43-6) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Name: N-(4-Hydroxyphenyl)-4-methylbenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Investigation of a homogeneous activating ozonation method in the rinsing procedure of cotton fabric dyed with reactive dye [Erratum to document cited in CA155:354636] was written by Mao, Ya-Hong;Guan, Yu;Luo, Deng-Hong;Zheng, Qing-Kang;Feng, Xi-Ning;Wang, Xiu-Xing. And the article was included in Coloration Technology in 2011.Synthetic Route of C10H16N2O4 This article mentions the following:

On page 265, in Table 7, in row 2, in column 4, the Peak II chem. formula, “C₄H₆ozone”, was incorrectly given, and should read: “C₄H₆O₃“. The correct version of the table is given. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Synthetic Route of C10H16N2O4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Synthetic Route of C10H16N2O4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

New development for combined bioscouring and bleaching of cotton-based fabrics was written by Hebeish, Ali;Hashem, Mohamed;Shaker, Nihal;Ramadan, Mohamed;El-Sadek, Bahiya;Hady, Marwa Abdel. And the article was included in Carbohydrate Polymers in 2009.Application of 10543-57-4 This article mentions the following:

A thorough investigation into conditions appropriate for effecting combined eco-friendly bioscouring and/or bleaching of cotton-based fabrics was undertaken. Fabrics used include cotton, gray mercerized cotton, cotton/polyester blend 50/50 and cotton/polyester blend 35/65. The four cotton-based fabric were subjected to bioscouring by single use of alk. pectinase enzymes or by using binary mixtures of alk. pectinase and cellulase enzymes under a variety of conditions. Results of bioscouring show that, the bioscoured substrates exhibit fabrics performances which are comparable with these of the conventional alkali scouring. Incorporation of EDTA in the bioscouring with a mixture of alk. pectinase and cellulase improves the performance of the bioscoured fabrics. Addition of β-cyclodextrin to the bioscouring solution using alk. pectinase in admixtures with cellulase acts in favor of tech. properties and performance of the bioscoured fabrics. Concurrent bioscouring and bleaching by in situ formed peracetic acid using tetraacetylethylenediamine (TAED) and H₂O₂ was also investigated. The results reveal unequivocally that the environmentally sound technol. brought about by current development is by far the best. The new development involves a single-stage process for full purification/preparation of cotton textiles. The new development at its best comprises treatment of the fabric with an aqueous formulation consisting of alk. pectinase enzyme (2 g/L), TAED (15 g/L), H₂O₂ (5 g/L), nonionic wetting agent (0.5 g/L) and sodium silicate (2 g/L). The treatment is carried out at 60 °C for 60 min. Beside the advantages of the new development with respect to major tech. fabric properties, it is eco-friendly and reproducible. This advocates the new development for mill trials. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Application of 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Application of 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Study on structure-activity relationship of mutation-dependent herbicide resistance acetohydroxyacid synthase through 3D-QSAR and mutation was written by Yu, ZhiHong;Niu, CongWei;Ban, ShuRong;Wen, Xin;Xi, Zhen. And the article was included in Chinese Science Bulletin in 2007.SDS of cas: 82097-01-6 This article mentions the following:

Seventy-four sulfonylureas were synthesized and tested for their inhibitory activity against the whole enzyme of E. coli acetohydroxyacid synthase (AHAS, EC 2.2.1.6) isoenzyme II, and 3D-QSAR analyses were performed based on these inhibitory activities. The binding conformation of chlorimuron-Et, a com. herbicidal AHAS inhibitor, in the crystal structure of AHAS complex was extracted and used as template to build the initial three-dimensional structure of other sulfonylureas, and then all structures were fully geometrically optimized. After systematic optimization of the alignment rule, mol. orientation, grid space and attenuation factor, two satisfactory models with excellent performances (CoMFA: q² = 0.735, r² = 0.954, n = 7, r²_pred = 0.832; CoMSIA: q² = 0.721, r² = 0.913, n = 8, r²_pred = 0.844) were established. By mapping the 3D contour maps of CoMFA and CoMSIA models into the possible inhibitory active site in the crystal structure of catalytic subunit of yeast AHAS, a plausible binding model for AHAS, with best fit QSAR in the literature so far, was proposed. The results of 3D-QSAR were further utilized to interpret resistance of site-directed mutants. A relative activity index (RAI) for AHAS enzyme mutant was defined for the first time to relate the 3D-QSAR and resistance of mutants. This study, for the first time, demonstrated that combination of 3D-QSAR and enzyme mutation can be used to decipher the mol. basis of ligand-receptor interaction mechanism. This study refined our understanding of the ligand-receptor interaction and resistance mechanism in AHAS-sulfonylurea system, and provided basis for designing new potent herbicides to combat the herbicide resistance. In the experiment, the researchers used many compounds, for example, 2-(2-Chloroethoxy)benzenesulfonamide (cas: 82097-01-6SDS of cas: 82097-01-6).

2-(2-Chloroethoxy)benzenesulfonamide (cas: 82097-01-6) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 82097-01-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Solid lipid nanoparticles based on L-cysteine for progesterone intravaginal delivery was written by Cassano, Roberta;Trombino, Sonia. And the article was included in International Journal of Polymer Science in 2019.Application of 2387-23-7 This article mentions the following:

The present work has as its purpose the synthesis and characterization of a novel lipid material to be used in the preparation of solid lipid nanoparticles (SLNs) for the potential sustained release of progesterone in the vagina. For this reason, a material capable of ensuring the permanence of the formulation in the administration site for the time needed to guarantee the transmucosal absorption of the steroid was synthesized in order to reduce the number of administrations and to ensure an effective concentration of drug at the site of action. To this end, an ester, 2,3-dihydroxypropanoate of octadecyl (stearyl glycerin), containing two hydroxyl groups was initially synthesized. In particular, the hydroxyl group less sterically encumbered was functionalized with a thiol group, in a coupling reaction, with the amino acid L-cysteine. The obtained compound was characterized by FT-IR spectrometry and ¹H-NMR. The functionalized lipid with L-cysteine was then used for the preparation of solid lipid nanoparticles that were loaded with progesterone. Finally, the release of progesterone from the lipid matrix based on newly synthesized ester, under conditions that simulate the vaginal physiol. environment, was evaluated. All the obtained results suggest that the prepared nanoparticles could be used for the administration of progesterone, when its integration is essential, for example, in cases of threats of abortion or to increase fertility. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Application of 2387-23-7).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 2387-23-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Effect of pretreated acetic anhydride and reaction conditions on the black by-product in synthesis of tetraacetylethylenediamine was written by Mo, Zai-yong;Liang, Chun-jie;Liu, Ning;Wu, Dan-yun. And the article was included in Yinran Zhuji in 2011.Category: amides-buliding-blocks This article mentions the following:

Tetraacetylethylenediamine was synthesized using diacetylethylenediamine (DAED) with the untreated or pretreated acetic anhydride. The effect of reaction temperature, time and the molar ratio of acetic anhydride to DAED on the absorbency of product were investigated. The results showed that reaction temperature and time had obvious effect on the generation of black byproduct, but the effect of materials ratio was little. Under the condition of temperature 130°C, 6:1 of molar ratio of acetic anhydride to DAED, over 360 min of reaction time, the absorbency of product synthesized by pretreated acetic anhydride, which was pretreated by sulfur trioxide, was less than one fifth of the un-pretreated. Pretreating acetic anhydride was a good method to evidently depress the black byproduct. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Category: amides-buliding-blocks).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis of trans-5-propyl-2-(4′-bromine-phenyl)-tetrahydropyran was written by Gao, Feng-qin;He, Han-jiang;Guo, Qiang;Wang, Xiao-ming;Li, Peng;Zhang, Yan-jun. And the article was included in Jingxi Huagong in 2012.Computed Properties of C9H10BrNO2 This article mentions the following:

The starting material of 4-bromobenzene carboxylic acid was acylated to generate acyl chloride. Then, acyl chloride reacted with N,O-di-Me hydroxylamine hydrochloride to synthesize the amides, which then reacted with chlorovinylmagnesium to synthesize α, β unsaturated ketone. Meanwhile, allyl amine was synthesized from the reaction of pentanal with di-n-propylamine. By Michael addition reaction, α, β unsaturated ketone and allyl amine reacted to synthesize intramol. aldehyde and ketone, which further reacted to synthesize trans-5-propyl-2-(4′-bromine-phenyl)-tetrahydropyran (3PyPBr) with a purity of more than 99.5% by closed loop reaction and recrystallization with ethanol. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Computed Properties of C9H10BrNO2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Computed Properties of C9H10BrNO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis of 2-Benzylphenyl Ketones by Aryne Insertion into Unactivated C-C Bonds was written by Rao, Bin;Tang, Jinghua;Zeng, Xiaoming. And the article was included in Organic Letters in 2016.Related Products of 192436-83-2 This article mentions the following:

A transition-metal-free procedure to access functionalized 2-benzylphenyl ketones is described by direct insertion of arynes into benzylic C-C bonds. This reaction was promoted by cesium fluoride at room temperature, allowing the products to form in high selectivity and achieve good functional group tolerance. In the experiment, the researchers used many compounds, for example, 4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2Related Products of 192436-83-2).

4-Bromo-N-methoxy-N-methylbenzamide (cas: 192436-83-2) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Related Products of 192436-83-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Antimicrobial efficacy of hygiene rinsers under consumer-related conditions was written by Lucassen, Ralf;Merettig, Nadine;Bockmuehl, Dirk P.. And the article was included in Tenside, Surfactants, Detergents in 2013.Safety of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) This article mentions the following:

In domestic laundry, the question how to achieve a sufficient germ reduction gains importance since the trend towards lower washing temperatures and the incremental use of bleach-free liquid detergents does not ensure a sufficient hygiene by the means of temperature and bleach any longer. Hygiene rinsers as products being added to the rinse cycle offer further antimicrobial efficacy and seem to provide an adequate solution for this challenge. However, their regular application is debated due to the used ingredients and it is still unclear whether they are able to exhibit an addnl. antimicrobial efficacy. This study investigates the germ reduction by a supplementary use of hygiene rinsers under conditions that are close to the parameters found in the household to evaluate the benefit of these products for the hygienic reconditioning of laundry. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Safety of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Safety of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Synthesis and antibacterial activity of novel vanillic acid hybrid derivatives was written by Satpute, Maruti S.;Gangan, Vijay D.;Shastri, Indu. And the article was included in Rasayan Journal of Chemistry in 2019.Electric Literature of C13H24N2O This article mentions the following:

Novel ester / hybrid derivatives of vanillic acid were synthesized and tested for potential antibacterial activity. This combinatorial synthesis of novel vanillic ester / hybrid derivatives was useful approach to generate potent chemotherapeutic agents in developing new drug candidates. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Electric Literature of C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Electric Literature of C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics