Tag: 200-300

A Catalytic Route to Pyrrole Derivatives via Copper-catalyzed Multicomponent Reaction was written by Samzadeh-Kermani, Alireza;Ghasemi, Samira. And the article was included in Journal of Heterocyclic Chemistry in 2019.Computed Properties of C13H24N2O This article mentions the following:

In the presence of CuI, Bu₄P⁺·AcO^–, and DBU in MeCN, terminal alkynes R¹CCH (R¹ = Ph, 3-MeC₆H₄, 3-MeOC₆H₄, 2-furyl, 2-thienyl, Bu, PhCH₂CH₂, Me₃Si), carbodiimides R²N:C:NR³ (R² = R³ = cyclohexyl, i-Pr, Ph; R² = Ph, 4-MeC₆H₄, 4-ClC₆H₄, R³ = cyclohexyl; R² = Ph, R³ = Bu), and malononitrile underwent regioselective three-component coupling and cyclization reactions to yield (alkylidene)iminopyrrolinecarbonitriles I (R¹ = Ph, 3-MeC₆H₄, 3-MeOC₆H₄, 2-furyl, 2-thienyl, Bu, PhCH₂CH₂, Me₃Si; R² = R³ = cyclohexyl, i-Pr, Ph; R² = Ph, 4-MeC₆H₄, 4-ClC₆H₄, R³ = cyclohexyl; R² = Ph, R³ = Bu). In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Computed Properties of C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Computed Properties of C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

The study on loss in strength of fabrics oxygen bleached with PB/TAED was written by Wan, Yingying. And the article was included in Ranliao Yu Ranse in 2012.Name: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) This article mentions the following:

The powder detergent containing PB/TAED activated oxygen bleaching system was employed to wash the cotton fabrics which dyed by four kinds of reactive dyes. The fabric tensile strength, K/S and color deviation of the fabrics before and after washing were determined in the conditions of different dyes, detergents and temperature by orthogonal test. The study results provided reference basis for better fabric care. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Name: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Name: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Manganese Catalyzed Hydrogenation of Carbamates and Urea Derivatives was written by Das, Uttam Kumar;Kumar, Amit;Ben-David, Yehoshoa;Iron, Mark A.;Milstein, David. And the article was included in Journal of the American Chemical Society in 2019.Formula: C13H24N2O This article mentions the following:

We report the hydrogenation of carbamates and urea derivatives, two of the most challenging carbonyl compounds to be hydrogenated, catalyzed for the first time by a complex of an earth-abundant metal. The hydrogenation reaction of these CO₂-derived compounds, catalyzed by a manganese pincer complex, yields methanol in addition to amine and alc., which makes this methodol. a sustainable alternative route for the conversion of CO₂ to methanol, involving a base-metal catalyst. Moreover, the hydrogenation proceeds under mild pressure (20 bar). Our observations support a hydrogenation mechanism involving the Mn-H complex. A plausible catalytic cycle is proposed based on informative mechanistic experiments In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Formula: C13H24N2O).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Formula: C13H24N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

C-H Oxygenation Reactions Enabled by Dual Catalysis with Electrogenerated Hypervalent Iodine Species and Ruthenium Complexes was written by Massignan, Leonardo;Tan, Xuefeng;Meyer, Tjark H.;Kuniyil, Rositha;Messinis, Antonis M.;Ackermann, Lutz. And the article was included in Angewandte Chemie, International Edition in 2020.Synthetic Route of C10H10F3NO2 This article mentions the following:

The catalytic generation of hypervalent iodine(III) reagents by anodic electrooxidation was orchestrated towards an unprecedented electrocatalytic C-H oxygenation of weakly coordinating aromatic amides and ketones. Thus, catalytic quantities of iodoarenes in concert with catalytic amounts of ruthenium(II) complexes set the stage for versatile C-H activations with ample scope and high functional group tolerance. Detailed mechanistic studies by experiment and computation substantiate the role of the iodoarene as the electrochem. relevant species towards C-H oxygenations with electricity as a sustainable oxidant and mol. hydrogen as the sole byproduct. Para-Selective C-H oxygenations likewise proved viable in the absence of directing groups. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Synthetic Route of C10H10F3NO2).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Synthetic Route of C10H10F3NO2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Combined scouring and bleaching of cotton/linen blends by a near-neutral activated peroxide system was written by Li, Ling;Li, Qing. And the article was included in Fibres & Textiles in Eastern Europe in 2020.Recommanded Product: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) This article mentions the following:

The simultaneous scouring and bleaching of cotton/linen blends was performed in a near-neutral activated peroxide system (pH = 7.2). A response surface quadratic model (RSQM) based on the central composite design (CCD) was established to investigate and optimize the bleaching performance. Research results showed that hydrophobic impurities in the blends had little impact on the bleaching. Temperature was the most significant factor affecting the fabric’s whiteness index (WI), followed by the concentration and duration of the activator tetraacetylethylenediamine (TAED). The optimized process was performed at 70°C for 40 min, incorporating 20 mmol/l of TAED and 42 mmol/l of H₂O₂. Compared with the conventional process carried out at 95°C for 60 min and adding 80 mmol/l H₂O₂, the activation process provided the fabric with comparable WI and wettability, a smoother and cleaner microcosmic surface, as well as the advantages of saving energy and preserving fabric. This study confirmed the feasibility of an efficient one-step process for neutral scouring and bleaching. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Recommanded Product: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Examining the antimicrobial efficacy of granulated tetraacetylethylenediamine derived peracetic acid and commercial peracetic acid in urban wastewaters was written by Spencer-Williams, Isaiah;Theobald, Allister;Cypcar, Christopher C.;Casson, Leonard W.;Haig, Sarah-Jane. And the article was included in Water Environment Research in 2022.Recommanded Product: 10543-57-4 This article mentions the following:

The ever-increasing need for access to safe water has meant that alternative water sources and innovative water reclamation approaches are often required to meet the global water demand. As a result, many wastewater treatment facilities have faced regulatory pressure to seek alternative disinfection methods that ensure public health safety, while adhering to regulations that set limits on carcinogenic disinfection byproducts (DBPs). Peracetic acid (PAA) is an emerging wastewater disinfectant in the United States that has been widely used in other industries such as food sanitization and does not produce carcinogenic DBPs. However, several factors such as transport, storage, and phys. and chem. effects have stymied its widespread use in wastewater markets. Therefore, the purpose of this study was to examine the antimicrobial efficacy of an on-site generated PAA compared against a com. available PAA. Antimicrobial efficacy was assessed using standard fecal contamination indicators (i.e., total coliforms and Escherichia coli ) in six urban wastewater treatment facilities ranging in size and treatment processes. Overall, few statistical differences were found between the antimicrobial efficacies of on-site generated PAA and com. available PAA; however, before becoming more widely utilized, the on-site PAA should be tested against emerging fecal contamination indicators (e.g., human norovirus and enterovirus) and be assessed in terms of economic and sustainability impacts. Practitioner Points : Alternative Ct approaches should be considered when using disinfectants like PAA. On-site generated PAA can achieve the same level of disinfection as com. PAA. On-site generation of PAA may help further its use as a wastewater disinfectant. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Recommanded Product: 10543-57-4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: 10543-57-4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Thermoresponsive Complex Coacervate-Based Underwater Adhesive was written by Dompe, Marco;Cedano-Serrano, Francisco J.;Heckert, Olaf;van den Heuvel, Nicoline;van der Gucht, Jasper;Tran, Yvette;Hourdet, Dominique;Creton, Costantino;Kamperman, Marleen. And the article was included in Advanced Materials (Weinheim, Germany) in 2019.Recommanded Product: 1,3-Dicyclohexylurea This article mentions the following:

Sandcastle worms have developed protein-based adhesives, which they use to construct protective tubes from sand grains and shell bits. A key element in the adhesive delivery is the formation of a fluidic complex coacervate phase. After delivery, the adhesive transforms into a solid upon an external trigger. In this work, a fully synthetic in situ setting adhesive based on complex coacervation is reported by mimicking the main features of the sandcastle worm’s glue. The adhesive consists of oppositely charged polyelectrolytes grafted with thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) chains and starts out as a fluid complex coacervate that can be injected at room temperature Upon increasing the temperature above the lower critical solution temperature of PNIPAM, the complex coacervate transitions into a nonflowing hydrogel while preserving its volume-the water content in the material stays constant The adhesive functions in the presence of water and bonds to different surfaces regardless of their charge. This type of adhesive avoids many of the problems of current underwater adhesives and may be useful to bond biol. tissues. In the experiment, the researchers used many compounds, for example, 1,3-Dicyclohexylurea (cas: 2387-23-7Recommanded Product: 1,3-Dicyclohexylurea).

1,3-Dicyclohexylurea (cas: 2387-23-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 1,3-Dicyclohexylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

One-step synthesis of 4H-3,1-benzoxazin-4-ones from Weinreb amides and 1,4,2-dioxazol-5-ones via cobalt-catalyzed C-H bond activation was written by Tanimoto, Iku;Kawai, Kentaro;Sato, Akane;Yoshino, Tatsuhiko;Matsunaga, Shigeki. And the article was included in Heterocycles in 2019.Recommanded Product: 116332-61-7 This article mentions the following:

A one-step synthesis of 4H-3,1-benzoxazin-4-ones e.g., 2-phenyl-4H-benzo[d][1,3]oxazin-4-one from readily available Weinreb amides I (R = t-Bu, Ph, thiophen-2-yl, etc.) and 1,4,2-dioxazol-5-ones e.g., N-methoxy-N-methylbenzamide under Cp*Co(III) catalysis is described. The reactions proceeded in moderate to good yields with high functional group compatibility. In the experiment, the researchers used many compounds, for example, N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7Recommanded Product: 116332-61-7).

N-Methoxy-N-methyl-4-(trifluoromethyl)benzamide (cas: 116332-61-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Recommanded Product: 116332-61-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sodium percarbonate bleaching of cotton knitted fabric was written by Li, Qun-gen;Zhao, Tao. And the article was included in Yinran in 2010.Quality Control of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) This article mentions the following:

In this paper, the influences of concentration of sodium hydroxide, stabilizer EDTA, oxygen bleaching activator tetraacetylethylenediamine, sodium percarbonate and bleaching temperature and time on the whiteness and strength of the bleached fabric, and subsequent dyeing were investigated. The optimum bleaching process of knitted cotton fabric with sodium percarbonate was: sodium hydroxide 4 g/L, tetraacetylethylenediamine 1 g/L, EDTA 2 g/L, sodium percarbonate 10 g/L, bleaching at 80 °C for 60 min. Compared with traditional hydrogen peroxide bleaching, sodium percarbonate bleaching possessed lower temperature, shorter bleaching time, less dosage of sodium hydroxide, satisfactory whiteness and strength of the fabric, without adverse effect on the subsequent dyeing. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Quality Control of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Quality Control of N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide)

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

A sustainable one-step pretreatment of cotton gray fabric with 18-crown-6 as phase transfer in supercritical carbon dioxide was written by Zheng, Yuan-Bin;Jia, Jian-Xin;Shi, Wei;Long, Jia-Jie. And the article was included in Journal of Supercritical Fluids in 2021.Formula: C10H16N2O4 This article mentions the following:

With increasing awareness in environmental protection from the world, traditional pretreatment methods for textiles, which entail high costs and cause severe pollutions, can no longer meet the requirements of green and sustainable development in textile industry. Therefore, to explore a new pretreatment method to overcome those drawbacks is of great importance. In this work, green and environmentally friendly method was developed in supercritical carbon dioxide fluid to pretreat cotton gray fabric for removing various impurities with one step and one bath, by utilizing an 18-crown-6 phase transfer system. Various process parameters, such as the pH value of buffer solution, the dosage of phase transfer catalyst, hydrogen peroxide, buffer solution, and the system temperature, pressure, treatment duration, were investigated and optimized by employing the weight loss percent and the capillary rise height as assessment index. The obtained results show that the developed alkali-hydrogen peroxide one-step method involving the 18-crown-6 phase transfer system in supercritical carbon dioxide exhibits a good feasibility for the removal of various sizing agents and other impurities from cotton fabric, and a satisfactory pretreatment performance and efficiency were achieved. The pretreatment parameters showed an important and various effects on the pretreatment efficiency of cotton substrate during a phase transfer oxidative one-step process in supercritical carbon dioxide. Moreover, a phase transfer oxidative one-step process was also recommended for cotton gray fabric pretreatment in supercritical carbon dioxide, by achieving a fabric weight loss at 6.21% and a satisfactory capillary rise height at 8.0 cm under an optimized condition. Addnl., an oxidative one-step pretreatment mechanism by employing 18-crown-6 to phase transfer reactive species for cotton gray fabric in SCF-CO₂ was further supposed. In the experiment, the researchers used many compounds, for example, N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4Formula: C10H16N2O4).

N,N-(Ethane-1,2-diyl)bis(N-acetylacetamide) (cas: 10543-57-4) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C10H16N2O4

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics