Tag: 200-300

Majumdar, K. C. et al. published their research in Synlett in 2011 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Electric Literature of C13H11BrN2O

CuI/L-proline-catalyzed intramolecular aryl amination: an efficient route for the synthesis of 1,4-benzodiazepinones was written by Majumdar, K. C.;Ganai, Sintu. And the article was included in Synlett in 2011.Electric Literature of C13H11BrN2O The following contents are mentioned in the article:

An effective protocol for the synthesis of potentially bioactive benzo[e]chromeno[6,5-b][1,4]diazepine-3,8(7H,13H)-dione and dibenzo[b,e][1,4]diazepin-11(10H)-one derivatives in good to excellent yields has been achieved by CuI/L-Proline catalyzed coupling reaction as the key step. The methodol. offers clean reaction conditions and easy isolation of the products in 61-92% yields. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Electric Literature of C13H11BrN2O).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Electric Literature of C13H11BrN2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Nemazanyi, A. G. et al. published their research in Khimiya Geterotsiklicheskikh Soedinenii in 1991 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 83909-69-7

3-Amino-4-aryl-1(2H)-isoquinolones was written by Nemazanyi, A. G.;Volovenko, Y. M.;Silaeva, T. A.;Kornilov, M. Yu.;Babichev, F. S.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1991.Recommanded Product: 83909-69-7 The following contents are mentioned in the article:

The cyclocondensation of (nitro)halobenzamides I (R = NO2, H; R1 = Cl, F; R2 = H, Me, CH2Ph, Ph, 2-pyridyl) with ArCH2CN (Ar = substituted Ph) in presence of K2CO3 gave isoquinolones II in 61-83% yields. The deflection angle of aromatic ring in the 4-position was determined to be 61°. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Recommanded Product: 83909-69-7).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 83909-69-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hwang, Jong Yeon et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2010 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 83909-69-7

Discovery of halo-nitrobenzamides with potential application against human African trypanosomiasis was written by Hwang, Jong Yeon;Smithson, David;Connelly, Michele;Maier, Julie;Zhu, Fangyi;Guy, Kiplin R.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2010.SDS of cas: 83909-69-7 The following contents are mentioned in the article:

A series of halo-nitrobenzamides were synthesized and evaluated for their ability to block proliferation of Trypanosoma brucei brucei. A number of these compounds had significant activity against the parasite, particularly 2-chloro-N-(4-chlorophenyl)-5-nitrobenzamide which exhibited low micromolar inhibitory potency against T. brucei and selectivity towards both malaria and mammalian cells. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7SDS of cas: 83909-69-7).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 83909-69-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hsu, Wayne et al. published their research in Acta Crystallographica in 2010 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Electric Literature of C12H10N4O2

4,4′-[Oxalylbis(azanediyl)]dipyridinium bis(perchlorate) was written by Hsu, Wayne;Hsiao, Hui Lin;Chen, Jhy Der. And the article was included in Acta Crystallographica in 2010.Electric Literature of C12H10N4O2 The following contents are mentioned in the article:

In 4,4′-[oxalylbis(azanediyl)]dipyridinium diperchlorate, C12H12N4O22+·2ClO4–, the complete cation is generated by crystallog. inversion symmetry. In the crystal, the cations and anions are linked via N-H···O and N-H···(O,O) H bonds, forming a 3-dimensional framework. Crystallog. data are given. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7Electric Literature of C12H10N4O2).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Electric Literature of C12H10N4O2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Barak, Dinesh S. et al. published their research in Tetrahedron Letters in 2019 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.COA of Formula: C13H11BrN2O

NaNO2/I2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides was written by Barak, Dinesh S.;Mukhopadhyay, Sushobhan;Dahatonde, Dipak J.;Batra, Sanjay. And the article was included in Tetrahedron Letters in 2019.COA of Formula: C13H11BrN2O The following contents are mentioned in the article:

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramol. cyclization. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5COA of Formula: C13H11BrN2O).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.COA of Formula: C13H11BrN2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ghosh, Suman Kr et al. published their research in RSC Advances in 2016 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 34489-85-5

Deep eutectic solvent mediated synthesis of quinazolinones and dihydroquinazolinones: synthesis of natural products and drugs was written by Ghosh, Suman Kr;Nagarajan, Rajagopal. And the article was included in RSC Advances in 2016.Application of 34489-85-5 The following contents are mentioned in the article:

A mild and greener protocol was developed to synthesize substituted quinazolinones and dihydroquinazolinones via deep eutectic solvent (DES) mediated cyclization with a series of aliphatic, aromatic, and heteroaromatic aldehydes in good to excellent yields. This greener strategy was further utilized to synthesize various quinazolinone natural products and drugs. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Application of 34489-85-5).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Application of 34489-85-5

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sharif’yanova, L. N. et al. published their research in Zhurnal Analiticheskoi Khimii in 1981 | CAS: 730-25-6

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: N-(3,4-Dichlorophenyl)octanamide

Gas-chromatographic study of anilides of aliphatic carboxylic acids was written by Sharif’yanova, L. N.;Vigdergauz, M. S.. And the article was included in Zhurnal Analiticheskoi Khimii in 1981.Recommanded Product: N-(3,4-Dichlorophenyl)octanamide The following contents are mentioned in the article:

To develop methods of gas chromatog. anal. for 16 anilides, their retention indexes on 4 stationary phases were measured, sorption thermodn. functions calculated, and equations found which connect the logarithmic retention indexes with the mol. size. The methods developed were used to control the production of N-(4-methyl-3-chlorophenyl)propionamide. This study involved multiple reactions and reactants, such as N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6Recommanded Product: N-(3,4-Dichlorophenyl)octanamide).

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: N-(3,4-Dichlorophenyl)octanamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Choi, Eun Hyang et al. published their research in Saengyak Hakhoechi in 2007 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Isolation of melanin biosynthesis inhibitory compounds from the roots of Asarum sieboldii was written by Choi, Eun Hyang;Choi, Ji Young;Lee, Jong Gu;Oh, Joon Seok;Kim, Dong Chun;Lee, Hee Sang;Son, Jong Keun;Ryang, Son Ae;Kim, Jeong Ah;Lee, Seung Ho. And the article was included in Saengyak Hakhoechi in 2007.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Eight compounds were isolated from the roots of Asarum sieboldii and their structures were identified as (±)-car-3-ene-2,5-dione, (-)-asarinin, (-)-sesamin, eucarvone, methyleugenol , γ-asarone, pellitorine and asarinol A by anal. of spectral data. Among them, (-)-asarinin showed the most potent inhibitory effect on melanogenesis, with inhibition rate of 66%. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Quality Control of (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Tahmina, Hoque et al. published their research in Heterocycles in 2015 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Isolation of alkamides with death receptor-enhancing activities from Piper chaba was written by Tahmina, Hoque;Toume, Kazufumi;Arai, Midori A.;Sadhu, Samir K.;Ahmed, Firoj;Ishibashi, Masami. And the article was included in Heterocycles in 2015.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

In the screening program for natural bioactive compounds that enhance the expression of death receptor 5 (DR5), activity-guided fractionation of the Piper chaba (Piperaceae) root MeOH extract led to the isolation of four alkamides (1-4). Compounds 1, 3, and 4 enhanced DR5 promoter activity while pellitorine (3) exhibited TRAIL-resistance-overcoming activity. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sharma, Moni et al. published their research in Tetrahedron Letters in 2013 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 34489-85-5

Potassium carbonate mediated unusual transformation of 2,3-dihydroquinazolinone via cascade reaction was written by Sharma, Moni;Mahar, Rohit;Shukla, Sanjeev K.;Kant, Ruchir;Chauhan, Prem M. S.. And the article was included in Tetrahedron Letters in 2013.Recommanded Product: 34489-85-5 The following contents are mentioned in the article:

An unusual potassium carbonate mediated transformation of 2,3-dihydroquinazolinone by a one-pot operation is reported under mild conditions. In addition, it is interesting to report the regioselective transformation of 3-(2-bromophenyl)-2-isopropyl-2,3-dihydroquinazolin-4(1H)-one I from compound II. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Recommanded Product: 34489-85-5).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 34489-85-5

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics