Tag: 200-300

Balkrishna, Shah Jaimin et al. published their research in Organic Letters in 2010 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Related Products of 83909-69-7

Cu-Catalyzed Efficient Synthetic Methodology for Ebselen and Related Se-N Heterocycles was written by Balkrishna, Shah Jaimin;Bhakuni, Bhagat Singh;Chopra, Deepak;Kumar, Sangit. And the article was included in Organic Letters in 2010.Related Products of 83909-69-7 The following contents are mentioned in the article:

An efficient copper-catalyzed method for the synthesis of biol. important ebselen and related analogs containing a Se-N bond has been developed. This is the first report of a catalytic process of selenation and Se-N bond formation reaction. The copper-catalyzed reaction tolerates functional groups such as amides, hydroxyls, ethers, nitro, fluorides, and chlorides. The best results are obtained by using a combination of potassium carbonate as a base, iodo- or bromo-arylamide substrates, selenium powder, and copper iodide catalyst. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Related Products of 83909-69-7).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Related Products of 83909-69-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sattarova, O. E. et al. published their research in Pharmaceutical Chemistry Journal in 2006 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Safety of 2-Amino-N-(2-bromophenyl)benzamide

Synthesis and antimicrobial activity of 1,2-diaryl- and 2,3-diaryl-(2-aryl-3-n-arylamino)-1,2,3,4-tetrahydroquinazolin-4-ones was written by Sattarova, O. E.;Vizgunova, O. L.;Voronina, E. V.. And the article was included in Pharmaceutical Chemistry Journal in 2006.Safety of 2-Amino-N-(2-bromophenyl)benzamide The following contents are mentioned in the article:

A series of 2,3-diaryl, (2-aryl-3-N-arylamino)- and 1,2-diaryl-1,2,3,4-tetrahydroquinazolin-4-ones, e.g., I (R = Br or NO2) were obtained via reactions of arylamides and anthranilic acid phenylhydrazide or N-arylanthranilic acid amides with 5-bromo- or 5-nitrosalicylic aldehydes. One of these compounds was acetylated to obtain a triacetyl derivative The structures of the synthesized compounds were determined by spectral methods (1H NMR, IR) and their antimicrobial activity was evaluated. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Safety of 2-Amino-N-(2-bromophenyl)benzamide).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Safety of 2-Amino-N-(2-bromophenyl)benzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Bhakuni, Bhagat Singh et al. published their research in Tetrahedron Letters in 2012 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.COA of Formula: C14H11ClN2O3

An efficient copper mediated synthetic methodology for benzo[d]isothiazol-3(2H)-ones and related sulfur-nitrogen heterocycles was written by Bhakuni, Bhagat Singh;Balkrishna, Shah Jaimin;Kumar, Amit;Kumar, Sangit. And the article was included in Tetrahedron Letters in 2012.COA of Formula: C14H11ClN2O3 The following contents are mentioned in the article:

A copper mediated sulfur-nitrogen coupling reaction for the synthesis of benzo[d]isothiazol-3(2H)-ones and related sulfur-nitrogen heterocycles has been presented, which requires 2-halo arylamides, sulfur powder, 25-50 mol % of copper iodide/1,10-phenanthroline, and potassium carbonate as base. E.g., in presence of copper iodide/1,10-phenanthroline and sulfur powder, sulfur-nitrogen coupling reaction of 2-chloro-, 2-bromo-, and 2-iodo-N-benzylbenzamides gave benzo[d]isothiazol-3(2H)-one (I) in 47-89% yields. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7COA of Formula: C14H11ClN2O3).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.COA of Formula: C14H11ClN2O3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Vajpayee, Vaishali et al. published their research in Organometallics in 2011 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 53118-43-7

Coordination-Driven Self-Assembly and Anticancer Activity of Molecular Rectangles Containing Octahedral Ruthenium Metal Centers was written by Vajpayee, Vaishali;Song, Young Ho;Yang, Yoon Jung;Kang, Se Chan;Kim, Hyunuk;Kim, In Su;Wang, Ming;Stang, Peter J.;Chi, Ki-Whan. And the article was included in Organometallics in 2011.SDS of cas: 53118-43-7 The following contents are mentioned in the article:

The synthesis of new 2+2 metallarectangle macrocycles 1–3 via coordination-driven self-assembly of octahedral arene Ru(II)-based acceptors and dipyridyl amide ligand donors is described. To evaluate their in vitro cytotoxic properties, preliminary biol. assays were carried out for various human cancer cell lines, and the results show that the cytotoxicity level of 3 is comparable or even greater in the cases of SK-hep-1 and HCT-15 than that of the reference drug cisplatin. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7SDS of cas: 53118-43-7).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.SDS of cas: 53118-43-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Paul, Rajesh et al. published their research in RSC Advances in 2012 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Name: N-Benzyl-2-chloro-5-nitrobenzamide

Copper-catalyzed one-pot synthesis of N-substituted benzo[d]isothiazol-3(2H)-ones via C-S/N-S bond formation was written by Paul, Rajesh;Punniyamurthy, Tharmalingam. And the article was included in RSC Advances in 2012.Name: N-Benzyl-2-chloro-5-nitrobenzamide The following contents are mentioned in the article:

A one-pot synthesis of N-substituted benzo[d]isothiazol-3(2H)-one derivatives was described using copper-catalysis and N-substituted 2-halobenzamides and sulfur powder by a C-S/N-S bond formation with high yield. The title compounds thus formed included 5-methoxy-2-(phenylmethyl)-1,2-benzisothiazol-3(2H)-one (I) and related substances. The synthesis of the target compound was achieved by a copper chloride (CuCl) catalyzed reaction of sulfur with 2-iodo-5-methoxy-N-(phenylmethyl)benzamide. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Name: N-Benzyl-2-chloro-5-nitrobenzamide).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Name: N-Benzyl-2-chloro-5-nitrobenzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Shinde, B. R. et al. published their research in Indian Journal of Chemistry in 1990 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Application In Synthesis of N-Benzyl-2-chloro-5-nitrobenzamide

2-Mercapto-(1H)-1,3,2λ5-benzodiazaphosphorine-2,4-dithiones. Part I. Synthesis and spectral studies was written by Shinde, B. R.;Shenoy, S. J.;Pai, N. R.. And the article was included in Indian Journal of Chemistry in 1990.Application In Synthesis of N-Benzyl-2-chloro-5-nitrobenzamide The following contents are mentioned in the article:

The reaction of 2-H2NC6H4CONH2 with P2S5 in boiling pyridine leading to pyridine adduct of title compound I. The synthesis has been extended to a number of substituted anthranilamides to afford the new adducts. Newer adducts in which pyridine mol. is replaced by α- and γ-picolines and Et3N resp. have also been synthesized. 1H NMR and mass spectra of the products have been recorded and discussed. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Application In Synthesis of N-Benzyl-2-chloro-5-nitrobenzamide).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Application In Synthesis of N-Benzyl-2-chloro-5-nitrobenzamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Truong, Thi Thu Hien et al. published their research in Tap Chi Hoa Hoc in 2013 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Amides and α-tocopherol from the stem barks of Tetradium glabrifolium was written by Truong, Thi Thu Hien;Hoang, Le Tuan Anh;Pham, Hai Yen;Dan, Thi Thuy Hang;Nguyen, Thi Cuc;Duong, Thi Hai Yen;Duong, Thi Dung;Nguyen, Xuan Nhiem;Nguyen, Van Tuyen;Phan, Van Kiem. And the article was included in Tap Chi Hoa Hoc in 2013.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Three amides, N-isobutyl-2E,4E-tetradecadienamide (1), N-isobutyl-2E,4E-decadienamide (pellitorine) (2), N-isobutyl-2E,4E,8Z-tetradecatrienamide (3), and α-tocopherol (4) were isolated from the methanol extract of barks of Tetradium glabrifolium by various chromatog. experiments The structure elucidation of isolated compounds was done by spectroscopic methods including FT-ICR-MS, 1D- and 2D-NMR, and in comparison with the literature values. This is the first report of 1-4 from Tetradium genus. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Nemazanyi, A. G. et al. published their research in Doklady Akademii Nauk Ukrainskoi SSR in 1989 | CAS: 83909-69-7

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 83909-69-7

New approach to the synthesis of polyfunctional isoquinolones was written by Nemazanyi, A. G.;Volovenko, Yu. M.;Silaeva, T. A.;Babichev, F. S.. And the article was included in Doklady Akademii Nauk Ukrainskoi SSR in 1989.Recommanded Product: 83909-69-7 The following contents are mentioned in the article:

The title isoquinolones I (R1 = H, R2 = NO2, R3 = H, Me, Ph, PhCH2, 4-MeOC6H4; R1 = Cl, R2 = H, R3 = H, Me; R1-R3 = H) were prepared in 54-93% yields by treating the corresponding benzamides II (R4 = H, Me, X = Cl, F) with CH2(CN)2 in DMF containing K2CO3. This study involved multiple reactions and reactants, such as N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7Recommanded Product: 83909-69-7).

N-Benzyl-2-chloro-5-nitrobenzamide (cas: 83909-69-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 83909-69-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Hansch, Corwin et al. published their research in Biochimica et Biophysica Acta, Biophysics Including Photosynthesis in 1966 | CAS: 730-25-6

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.SDS of cas: 730-25-6

The structure-activity relation in amides inhibiting photosynthesis was written by Hansch, Corwin;Deutsch, Edna W.. And the article was included in Biochimica et Biophysica Acta, Biophysics Including Photosynthesis in 1966.SDS of cas: 730-25-6 The following contents are mentioned in the article:

By using substituent constants and regression analysis, the effect of various substituents on several groups of Hill-reaction inhibitors were studied. The primary effect of substituents in altering the activity of a parent phenylcarbamate, anilide, or phenylurea was associated with the hydrophobic bonding power of the substituent. The stronger the function bound hydrophobically, the greater was its inhibitory power on the photosynthetic reaction in isolated chloroplasts. This study involved multiple reactions and reactants, such as N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6SDS of cas: 730-25-6).

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.SDS of cas: 730-25-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Cremlyn, Richard J. et al. published their research in Journal of Chemical and Engineering Data in 1974 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C12H10N4O2

Synthesis and spectral data for some derivatives of N-aryloxamic acid hydrazides was written by Cremlyn, Richard J.. And the article was included in Journal of Chemical and Engineering Data in 1974.Formula: C12H10N4O2 The following contents are mentioned in the article:

By condensation of diethyl oxalate with aromatic amines, 21 ethyl N-aryloxamates were prepared Subsequent reaction with hydrazine afforded the corresponding N-aryloxamic acid hydrazides; these were converted into 80 hydrazones, 10 N-phosphoryl, 26 N-sulfonyl, nine N,N-dimethylcarbamoyl, and six N-ethoxycarbonyl derivatives The ir and NMR spectral data of the various comds. were given. The compounds have bactericidal, fungicidal, and insecticidal activity (no data). This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7Formula: C12H10N4O2).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C12H10N4O2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics