Tag: 200-300

Vajpayee, Vaishali et al. published their research in Organometallics in 2013 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Synthetic Route of C12H10N4O2

Growth Inhibitory Activity of a Bis-Benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and -Prism was written by Vajpayee, Vaishali;Lee, Sun mi;Park, Joeng Woo;Dubey, Abhishek;Kim, Hyunuk;Cook, Timothy R.;Stang, Peter J.;Chi, Ki-Whan. And the article was included in Organometallics in 2013.Synthetic Route of C12H10N4O2 The following contents are mentioned in the article:

Two new supramol. coordination complexes (SCCs) were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, with dipyridyl and tripyridyl donors, resp. As part of a growing library of anticancer-active Ru-based SCCs, the self-assembled metalla-prism motif selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 μM for MCF7 cells, as determined from MTS assays. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7Synthetic Route of C12H10N4O2).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. The solubilities of amides and esters are roughly comparable. Typically amides are less soluble than comparable amines and carboxylic acids since these compounds can both donate and accept hydrogen bonds. Tertiary amides, with the important exception of N,N-dimethylformamide, exhibit low solubility in water. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Synthetic Route of C12H10N4O2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Pan, Zi-Cai et al. published their research in Acta Crystallographica in 2008 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Product Details of 53118-43-7

Bis(4-aminopyridinium) bis(oxalato-κ2O,O’)cuprate(II) dihydrate was written by Pan, Zi-Cai;Zhang, Kou-Lin;Ng, Seik Weng. And the article was included in Acta Crystallographica in 2008.Product Details of 53118-43-7 The following contents are mentioned in the article:

The CuII atom in bis(4-aminopyridinium) bis(oxalato-κ2O,O’)cuprate(2-) dihydrate, (C5H7N2)2[Cu(C2O4)2]·2H2O, is located on a center of inversion and is chelated by 2 oxalate groups in a square-planar coordination geometry. The cation, anion and H2O mols. interact through H bonds, forming a 3-dimensional H-bonded network. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7Product Details of 53118-43-7).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Product Details of 53118-43-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Tang, Gui-Hua et al. published their research in Journal of Natural Products in 2011 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Cytotoxic Amide Alkaloids from Piper boehmeriaefolium was written by Tang, Gui-Hua;Chen, Dong-Mei;Qiu, Bei-Ying;Sheng, Li;Wang, Yue-Hu;Hu, Guang-Wan;Zhao, Fu-Wei;Ma, Li-Juan;Wang, Huan;Huang, Qiao-Qin;Xu, Jin-Jin;Long, Chun-Lin;Li, Jia. And the article was included in Journal of Natural Products in 2011.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Eight new amide alkaloids (1-8) and 19 known ones were isolated from the whole plant of Piper boehmeriaefolium. Their structures were determined through spectroscopic data analyses. Cytotoxic activity of these amides against human cervical carcinoma HeLa cells was evaluated, and 1-[(9E)-10-(3,4-methylenedioxyphenyl)-9-decenoyl]pyrrolidine (9) exhibited significant inhibitory activity with an IC50 value of 2.7 μg/mL. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Name: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Jaganmohan, Chikkanti et al. published their research in Heterocyclic Letters in 2019 | CAS: 34489-85-5

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 34489-85-5

Boron tribromide catalysed facile and efficient synthesis of 2,3-disubstituted Quinazolinone derivatives was written by Jaganmohan, Chikkanti;Rao, Vinti S. P.;Shiva Prakash, P.;Vinay Kumar, K. P.;Mohanty, Sandeep;Kumar, Jaydeep;Venkateswara Rao, B.;Raghunadh, Akula. And the article was included in Heterocyclic Letters in 2019.Recommanded Product: 34489-85-5 The following contents are mentioned in the article:

A simple, convenient synthetic protocols have been developed for the synthesis of 2,3-disubstituted quinazolinone derivatives I (R = Me, Ph, 4-methoxyphenyl, etc.) using borontribromide as efficient catalyst. This reaction proceeds under mild conditions. This method was found to be better method giving high yields. The present method shows some advantages such as short reaction times and enhanced selectivity. This study involved multiple reactions and reactants, such as 2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5Recommanded Product: 34489-85-5).

2-Amino-N-(2-bromophenyl)benzamide (cas: 34489-85-5) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 34489-85-5

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Chen, Xiao-qing et al. published their research in Zhongguo Zhongyao Zazhi in 2015 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 18836-52-7

Study on chemical constituents of achillea alpina was written by Chen, Xiao-qing;Wang, Meng;Zhang, Xin;Guo, Wei-wei;Wu, Xia. And the article was included in Zhongguo Zhongyao Zazhi in 2015.Recommanded Product: 18836-52-7 The following contents are mentioned in the article:

Twelve compounds were isolated from the aerial parts of achillea alpina by column chromatogs. on silica gel, Sephadex LH-20, and semi-preparative HPLC. The structures were elucidated on the basis of spectral anal. The compounds were identified as pellitorine(1), 8,9-dehydropellitorine(2), (E, E)-2,4-undecadien-8,10-diynoic acid isobutylamide(3), (E,E)-2, 4-tetradecadien-8,10-diynoic acid isobutylamide(4), sintenin(5), 4′,5,7,8-tetramethoxyflavone(6), chrysoplenetin(7), formononetin(8), aurantiamide(9), asperglaucide(10), artemetin(11), and eupatorin(12). Compounds 1-5 were isolated from this plant for the first time, and compounds 6-10 were isolated from the genus achillea for the first time. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Recommanded Product: 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Kuai, Hai-Wei et al. published their research in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences in 2014 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.SDS of cas: 53118-43-7

Synthesis and structural characterization of a Cu(II) coordination polymer from N1,N2-Di(pyridin-4-yl)oxalamide was written by Kuai, Hai-Wei;Hu, Tao;Jiang, Ding-Yun;Qian, Yun-Hua;Li, Deng-Hao. And the article was included in Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences in 2014.SDS of cas: 53118-43-7 The following contents are mentioned in the article:

The reaction of Cu(NO3)2·3H2O with N1,N2-di(pyridin-4-yl)oxalamide (L) and KSCN in the presence of DMF by the layering method gives rise to a new complex [Cu(L2)(SCN)2(DMF)2]n (1). Complex 1 was characterized by single-crystal and powder x-ray diffraction, IR spectroscopy, and elemental and thermogravimetric analyses. It crystallizes in the triclinic system with space group P1̅ and shows a chain structure. Delicate N-H···O hydrogen bonding exists in individual units, and adjacent chains are linked by intermol. interactions, resulting in an extended 2D network. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7SDS of cas: 53118-43-7).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.SDS of cas: 53118-43-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Lee, Seung Woong et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2008 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Category: amides-buliding-blocks

Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition was written by Lee, Seung Woong;Kim, Young Kook;Kim, Koanhoi;Lee, Hyun Sun;Choi, Jung Ho;Lee, Woo Song;Jun, Chang-Duk;Park, Jee Hun;Lee, Jeong Min;Rho, Mun-Chual. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2008.Category: amides-buliding-blocks The following contents are mentioned in the article:

Eight alkamides 1-8 were isolated by bioassay-guided isolation of EtOH extracts of the fruits of Piper longum and Piper nigum (Piperaceae). Their structures were elucidated by spectroscopic anal. (1H, 13C NMR, and ESI-MS) as follows: guineensine (1), retrofracamide C (2), (2E,4Z,8E)-N-[9-(3,4-methylenedioxyphenyl)-2,4,8-nonatrienoyl]piperidine (3), pipernonaline (4), piperrolein B (5), piperchabamide D (6), pellitorin (7), and dehydropipernonaline (8). Their compounds 3-5, 7, and 8 inhibited potently the direct binding between sICAM-1 and LFA-1 of THP-1 cells in a dose-dependent manner, with IC50 values of 10.7, 8.8, 13.4, 13.5, and 6.0 μg/mL, resp. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Category: amides-buliding-blocks).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. Amides are stable compounds. The lower-melting members (such as acetamide) can be readily purified by fractional distillation. Most amides are solids which have low solubilities in water.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Nobsathian, Saksit et al. published their research in Natural Product Research in 2012 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Synthetic Route of C14H25NO

A new conjugated amide-dimer from the aerial parts of Piper submultinerve was written by Nobsathian, Saksit;Tuchinda, Patoomratana;Soorukram, Darunee;Pohmakotr, Manat;Reutrakul, Vichai;Yoosook, Chalobon;Kasisit, Jitra;Napaswad, Chanita. And the article was included in Natural Product Research in 2012.Synthetic Route of C14H25NO The following contents are mentioned in the article:

Bioassay-guided fractionation and purification of the aerial parts of Piper submultinerve led to the isolation of a new conjugated amide-dimer, submultinamide A (1), along with 11 known compounds The structures were determined on the basis of spectroscopic methods. Among the tested compounds, pellitorine (2), guineensine (4), N-benzylcinnamide (6) and aristolactam BII (8) showed significant activities in the anti-syncytium assay using ΔTat/RevMC99 virus and 1A2 cell line system, whereas was most active (EC50 35.1 μM and selectivity index 4.7). In the HIV-1 reverse transcriptase assay, only was active with IC50 50.8 μM. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Synthetic Route of C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Synthetic Route of C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Jun et al. published their research in Natural Products and Bioprospecting in 2013 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Recommanded Product: 18836-52-7

New amide alkaloids from Piper longum fruits was written by Yang, Jun;Su, Yao;Luo, Ji-Feng;Gu, Wei;Niu, Hong-Mei;Li, Yan;Wang, Yue-Hu;Long, Chun-Lin. And the article was included in Natural Products and Bioprospecting in 2013.Recommanded Product: 18836-52-7 The following contents are mentioned in the article:

Three new amide alkaloids piperlongumamides A-C (1-3), together with 12 known ones (4-15), were isolated from the fruits of Piper longum. The structures of the new isolates were determined using spectroscopic data analyses. Cytotoxic activity of these amides against HL-60 (human leukemia), A-549 (human lung cancer), MCF-7 (human breast cancer), SMMC-7721 (human liver cancer) and SW480 (human rectal cancer) cell lines were evaluated. Piperchabamide B (11) exhibited weak inhibitory activity against HL-60 (IC50 = 21.32 μM ), A-549 (IC50 = 23.82 μM ) and MCF-7 (IC50 = 16.58 μM ) cell lines. [Figure not available: see fulltext.]. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. In simple aromatic amides, fragmentation occurs on both sides of the carbonyl group. If a hydrogen is available in N-substituted aromatic amides, it tends to migrate and form an aromatic amine and the loss of a ketene.Recommanded Product: 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Lazarevic, Jelena et al. published their research in Natural Product Research in 2010 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Product Details of 18836-52-7

Composition of Achillea distans Willd. subsp. distans root essential oil was written by Lazarevic, Jelena;Radulovic, Niko;Zlatkovic, Bojan;Palic, Radosav. And the article was included in Natural Product Research in 2010.Product Details of 18836-52-7 The following contents are mentioned in the article:

Gas chromatog. and gas chromatog./mass spectrometry analyses of root volatiles of Achillea distans Willd. subsp. distans, collected from wild populations in Serbia, enabled the identification of 185 constituents, accounting for 93.6% of the total oil. Main constituents of the oil were τ-cadinol (17.6%), alismol (14.1%), α-cadinol (9.1%), and caryophyllene oxide (5.0%). The root oil was addnl. characterized by the presence of 5 different amides containing the olefinic C10 acid moieties. This is the first report on A. distans subsp. distans root volatiles and on the occurrence of piperidides and piperideides as essential oil constituents. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Product Details of 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Product Details of 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics