Buzon, Beverlee et al. published their research in ACS Omega in 2021 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Category: amides-buliding-blocks

Identification of Bioactive SNM1A Inhibitors was written by Buzon, Beverlee;Grainger, Ryan A.;Rzadki, Cameron;Huang, Simon York Ming;Junop, Murray. And the article was included in ACS Omega in 2021.Category: amides-buliding-blocks The following contents are mentioned in the article:

SNM1A is a nuclease required to repair DNA interstrand cross-links (ICLs) caused by some anticancer compounds, including cisplatin. Unlike other nucleases involved in ICL repair, SNM1A is not needed to restore other forms of DNA damage. As such, SNM1A is an attractive target for selectively increasing the efficacy of ICL-based chemotherapy. Using a fluorescence-based exonuclease assay, we screened a bioactive library of compounds for inhibition of SNM1A. Of the 52 compounds initially identified as hits, 22 compounds showed dose-response inhibition of SNM1A. An orthogonal gel-based assay further confirmed nine small mols. as SNM1A nuclease activity inhibitors with IC50 values in the mid-nanomolar to low micromolar range. Finally, three compounds showed no toxicity at concentrations able to significantly potentiate the cytotoxicity of cisplatin. These compounds represent potential leads for further optimization to sensitize cells toward chemotherapeutic agents inducing ICL damage. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Category: amides-buliding-blocks).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Oh, Joonseok et al. published their research in Archives of Pharmacal Research in 2010 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 18836-52-7

Anti-listerial compounds from Asari Radix was written by Oh, Joonseok;Hwang, In Hyun;Kim, Dong Chun;Kang, Sun-Chul;Jang, Tae-Su;Lee, Seung Ho;Na, Min Kyun. And the article was included in Archives of Pharmacal Research in 2010.Recommanded Product: 18836-52-7 The following contents are mentioned in the article:

Asari Radix, the roots of Asarum heterotropoides F. Maekawa var. manshuricum F. Maekawa or A. sieboldii F. Maekawa, has traditionally been used for the treatment of various infectious diseases. Since its MeOH extract inhibited the growth of Listeria monocytogenes in a preliminary test, the aim of this study was to isolate and identify the anti-listerial compounds from the plant. Activity-guided fractionation led to the isolation of seven compounds 1-7 from the MeOH extract, and their chem. structures were identified by comparison of the spectroscopic data with those in the literature. Compounds 1-7 exhibited inhibitory activity against all five tested strains of L. monocytogenes with diameter of inhibition zones ranging from 7 to 11 mm in the agar disk diffusion method. Compounds 1-3 and 7 demonstrated potent antimicrobial effects on the L. monocytogenes strains, with MICs between 62.5 and 125 μg/mL. This is the first report that AR possesses inhibitory activity against L. monocytogenes. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.Recommanded Product: 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Abdubakiev, Sardorbek et al. published their research in Natural Product Research in 2020 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

N-Alkylamides from Piper longum L. and their stimulative effects on the melanin content and tyrosinase activity in B16 melanoma cells was written by Abdubakiev, Sardorbek;Li, Hongliang;Lu, Xueying;Li, Jun;Aisa, H. A.. And the article was included in Natural Product Research in 2020.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide The following contents are mentioned in the article:

Piper longum L., known as long pepper, is an edible and medicinal plant used as spice and for the treatment of stomach disease and analgesia in traditional Chinese medicine. N-Alkylamides are the major secondary metabolites in this plant. Sixteen known N-alkylamides were isolated from P. longum. Their structures were established on the basis of spectroscopic data and comparison to reported literatures. Among them, five compounds were isolated from this plant for the first time. Ethanol extract, piperine, isopiperine, piperlonguminine, retrofractamide A, and retrofractamide C and exhibited potent ability to increase the melanin content and weak stimulative effect on the tyrosinase activity in a concentration-dependent manner. Moreover, isopiperine also presented strong capacity to increase the tyrosinase activity in a concentration-dependent manner. These results indicated that P. longum might be a good natural source of lead compound for skin disorder diseases. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.Recommanded Product: (2E,4E)-N-Isobutyldeca-2,4-dienamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Moreland, D. E. et al. published their research in Weeds in 1963 | CAS: 730-25-6

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Reference of 730-25-6

Inhibition of photochemical activity of isolated chloroplasts by acylanilides was written by Moreland, D. E.;Hill, K. L.. And the article was included in Weeds in 1963.Reference of 730-25-6 The following contents are mentioned in the article:

The effect of mono- and dichlorophenyl analogs of N-phenyl-2-methylpentanamide (I) and N-(3,4-dichlorophenyl) alkan-amides on the photolytic activity (Hill reaction) of chloroplasts isolated from turnip greens was studied. I inhibited the Hill reaction by 50% (I50) at 4.5 × 10-5M. Monochlorination in meta and para positions enhanced inhibition; ortho monochlorination negated inhibition. The N-(3,4-dichlorophenyl) analog was the most inhibitory of 6 dichlorinated isomers (I50 = 5.8 × 10-7M). The N-phenyl-N-(3,4-dichlorophenyl) analog, however, was less effective than unsubstituted I. Of the straight chain N-(3,4-dichlorophenyl) alkanamides, the propanamide was the most effective. 2-Methyl alkanamides were more effective than the corresponding straight-chain alkan-amides. Of these, N-(3,4-dichlorophenyl)-2-methylpropanamide was most effective. Kinetic studies indicate that both light and dark reactions are inhibited. This study involved multiple reactions and reactants, such as N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6Reference of 730-25-6).

N-(3,4-Dichlorophenyl)octanamide (cas: 730-25-6) belongs to amides. Compared to amines, amides are very weak bases and do not have clearly defined acid–base properties in water. On the other hand, amides are much stronger bases than esters, aldehydes, and ketones. As a result of interactions such as these, the water solubility of amides is greater than that of corresponding hydrocarbons. These hydrogen bonds are also have an important role in the secondary structure of proteins.Reference of 730-25-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Kuiyong et al. published their research in Analyst (Cambridge, United Kingdom) in 2013 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C14H25NO

Purification of amide alkaloids from Piper longum L. using preparative two-dimensional normal-phase liquid chromatography × reversed-phase liquid chromatography was written by Li, Kuiyong;Zhu, Wenya;Fu, Qing;Ke, Yanxiong;Jin, Yu;Liang, Xinmiao. And the article was included in Analyst (Cambridge, United Kingdom) in 2013.Formula: C14H25NO The following contents are mentioned in the article:

A comprehensive off-line two-dimensional liquid chromatog. (2D-LC) method coupling normal phase liquid chromatog. (NPLC) and reversed phase liquid chromatog. (RPLC) was developed for separation and purification of amide alkaloids from Piper longum. In the first dimension, the crude alkaloid fractions were separated in NPLC mode and 20 fractions were collected. Then fractions 5-20 were selected for further purification in RPLC mode in the second dimension. The purities of RPLC fractions with similar structures were all identified accurately by ultra performance liquid chromatog. (UPLC). In total, 28 compounds with high purity were obtained and their structures were comprehensively characterized by electrospray ionization-mass spectrometry (ESI-MS) and NMR spectroscopy. The results demonstrate that this 2D NPLC × RPLC method with good orthogonality (58.3%) was effective for the preparative separation and purification of amide alkaloids from Piper longum. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Formula: C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides can be freed from solvent or water by drying below their melting points. These purifications can also be used for sulfonamides and acid hydrazides.Formula: C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Seo, Seon-Mi et al. published their research in Industrial Crops and Products in 2021 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.SDS of cas: 18836-52-7

Larvicidal activities of Piper kadsura (Choisy) Ohwi extract and its constituents against Aedes albopictus, toxicity to non-target organisms and development of cellulose nanocrystal-stabilized Pickering emulsion was written by Seo, Seon-Mi;Shin, Jonghyun;Lee, Jae-Woo;Hyun, Jinho;Park, Il-Kwon. And the article was included in Industrial Crops and Products in 2021.SDS of cas: 18836-52-7 The following contents are mentioned in the article:

Among 15 plant methanol extracts, Piper kadsura stem extract (PkSE) showed the strongest larvicidal activity against Aedes albotictus. Larvicidal activities of P. kadsura stem extract were 100% and 80% at 0.01 and 0.005 mg/mL concentrations, resp. Two iso-Bu amides, pellitorine and chingchengenamide A, and one neolignan, piperenone, were isolated as active compounds from PkSE. Larvicidal activities of chingchengenamide A, piperenone, and pellitorine were 100%, 100%, and 87.5% at 0.005 mg/mL concentration, resp., and 100%, 67.5%, and 15.0% at 0.0025 mg/mL. Cellulose nanocrystal (CNC)-stabilized Pickering emulsion of PkSE was developed, and its larvicidal activity was slightly higher than that of pure PkSE. Acute oral and dermal toxicity of PkSE toward rat, Rattus norvegicus, was >2000 mg/kg body weight Acute contact toxicity of PkSE to honeybee was >100μg/bee. The no observed effect concentration (NOEC) of PkSE to Oryzias latipes was 0.031 mg/mL. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7SDS of cas: 18836-52-7).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group. Amides can be recrystallised from large quantities of water, ethanol, ethanol/ether, aqueous ethanol, chloroform/toluene, chloroform or acetic acid. The likely impurities are the parent acids or the alkyl esters from which they have been made. The former can be removed by thorough washing with aqueous ammonia followed by recrystallisation, whereas elimination of the latter is by trituration or recrystallisation from an organic solvent.SDS of cas: 18836-52-7

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wu, Siguo et al. published their research in Chinese Chemical Letters in 2022 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.COA of Formula: C12H10N4O2

Four-step spin-crossover in an oxamide-decorated metal-organic framework was written by Wu, Siguo;Bala, Sukhen;Ruan, Zeyu;Huang, Guozhang;Ni, Zhaoping;Tong, Mingliang. And the article was included in Chinese Chemical Letters in 2022.COA of Formula: C12H10N4O2 The following contents are mentioned in the article:

Spin-crossover (SCO) complexes with multiple spin states are promising candidates for high-order magnetic storage and multiple switches. Here, by employing the N,N’-4-dipyridyloxalamide (dpo) ligand, the authors synthesize two Hofmann-type metal-organic frameworks (MOFs) [Fe(dpo){Ag(CN)2}2]·3DMF (1) and [Fe(dpo){Ag(CN)2}2]·0.5MeCN·2DEF (2), which exhibit guest dependent four-step SCO behaviors with the sequences of LS → approx. LS2/3HS1/3 → LS1/2HS1/2 → approx. LS3/10HS7/10 → HS and LS → approx. LS2/3HS1/3 → LS1/2HS1/2 → approx. LS1/4HS3/4 → HS, resp. Therefore, the incorporation of hydrogen-donating/hydrogen-accepting groups into the Hofmann-type MOFs may effectively explore the multi-step SCO materials by tuning hydrogen-bonding interactions. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7COA of Formula: C12H10N4O2).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. In primary and secondary amides, the presence of N–H dipoles allows amides to function as H-bond donors as well. Thus amides can participate in hydrogen bonding with water and other protic solvents; the oxygen atom can accept hydrogen bonds from water and the N–H hydrogen atoms can donate H-bonds. The presence of the amide group –C(=O)N– is generally easily established, at least in small molecules. It can be distinguished from nitro and cyano groups in IR spectra. Amides exhibit a moderately intense νCO band near 1650 cm−1. By 1H NMR spectroscopy, CONHR signals occur at low fields. In X-ray crystallography, the C(=O)N center together with the three immediately adjacent atoms characteristically define a plane.COA of Formula: C12H10N4O2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Meepagala, Kumudini M. et al. published their research in Journal of Agricultural Chemistry and Environment in 2013 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Electric Literature of C14H25NO

Antibacterial compounds from Rutaceae with activities against Flavobacterium columnare and Streptococcus iniae was written by Meepagala, Kumudini M.;Schrader, Kevin K.;Burandt, Charles L.. And the article was included in Journal of Agricultural Chemistry and Environment in 2013.Electric Literature of C14H25NO The following contents are mentioned in the article:

From the Et acetate extract of Murraya koenegii (Rutaceae) leaves, isomahanine (1) and mahanine (2) were isolated that showed anti-bacterial activity towards Flavobacterium columnare and Streptococcus iniae which caused columnaris disease and streptococcosis resp. Isomahanine was found to have the strongest activity against F. columnare (isolate ALM-00-173) and S. iniae (isolate LA94-426) based on 24-h 50% inhibition concentration (IC50) and min. inhibition concentration (MIC). Although compound (7), a nicotinamide isolated from Amyris texana had the lowest MIC (2.8 ± 0 mg/L) of any of the test compounds against F. columnare, the 24-h IC50 of 14.8 ± 0.6 mg/L was higher than that of isomahanine and subsequently the 24-h IC50 RDC values for (7) were almost a magnitude of order higher than those obtained for isomahanine. Isomahanine also had the strongest activity against S. iniae, with a 24-h IC50 of 1.3 ± 0.1 mg/L and MIC of 3.5 ± 0 mg/L, resp. This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Electric Literature of C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. Amides are not in general accessible by the direct condensation of amines with carboxylic acids for two reasons: first, both components are readily deactivated by a transfer of a proton from the acid to the amine and second, the hydroxy unit on the carbonyl of the acid is a relatively poor leaving group. Nevertheless, the formation of five- and six-membered rings is often surprisingly simple provided that other factors can be brought into play to assist in the condensation.Electric Literature of C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Afshariazar, Farzaneh et al. published their research in Chemistry – A European Journal in 2020 | CAS: 53118-43-7

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Electric Literature of C12H10N4O2

Removal rate of Pb Ions through functionalized decoration of MOF cavity was written by Afshariazar, Farzaneh;Morsali, Ali;Wang, Jun;Junk, Peter C.. And the article was included in Chemistry – A European Journal in 2020.Electric Literature of C12H10N4O2 The following contents are mentioned in the article:

To overcome the challenge of developing a multipurpose adsorbent for effective removal of toxic and carcinogenic PbII ions from aqueous solutions, a made-for-purpose functional group (N1,N2-di(pyridine-4-yl)oxalamide) was rationally designed and incorporated into the cavities of a Zn metal-organic framework (MOF), namely, TMU-56. Large enough pore size along with high densities of strong metal chelating sites lead not only to the highest uptake capacity for PbII ions, but also the fastest removal rate that has ever been reported for functionalized MOFs, occurring in just 20 s. Moreover, high concentrations of lead ions favor the ion exchange reaction, resulting in a high degree of metal exchange. In addition, TMU-56 can be a practical adsorbent because of its notable performance in the simultaneous removal of several toxic and carcinogenic heavy metals from wastewater, which has rare precedence. This study involved multiple reactions and reactants, such as N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7Electric Literature of C12H10N4O2).

N1,N2-Di(pyridin-4-yl)oxalamide (cas: 53118-43-7) belongs to amides. Because of the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N–C dipole. The presence of a C=O dipole and, to a lesser extent a N–C dipole, allows amides to act as H-bond acceptors. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Electric Literature of C12H10N4O2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Sun, Cuirong et al. published their research in Rapid Communications in Mass Spectrometry in 2007 | CAS: 18836-52-7

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Electric Literature of C14H25NO

Rapid structural determination of amides in Piper longum by high-performance liquid chromatography combined with ion trap mass spectrometry was written by Sun, Cuirong;Pei, Saifeng;Pan, Yuanjiang;Shen, Zhiquan. And the article was included in Rapid Communications in Mass Spectrometry in 2007.Electric Literature of C14H25NO The following contents are mentioned in the article:

A reversed-phase liquid chromatog./tandem multistage mass spectrometry (MS/MS) method was developed for the characterization of amides from the extracts of Piper longum. The characteristic fragmentations of the amides found in P. longum showed diagnostic structural information. Extracted ion chromatog. (EIC) and constant neutral losses were used to guide the search for the amides of interest. Amides of known structures that contain four subtypes of amides were rapidly determined, and novel amides were also identified for this plant. Forty-two amides were rapidly identified, of which 22 were found in this plant for the first time and 9 were new compounds The method is convenient and sensitive, especially for minor components in the unpurified, complex mixture; the structures of unknown constituents could be determined, in the absence of authentic sample, by comparison of the fragmentation patterns with those of homologous compounds This study involved multiple reactions and reactants, such as (2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7Electric Literature of C14H25NO).

(2E,4E)-N-Isobutyldeca-2,4-dienamide (cas: 18836-52-7) belongs to amides. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents. Ionic, or saltlike, amides are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent amide with a reactive metal such as sodium.Electric Literature of C14H25NO

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics