Tag: 200-300

Heppolette, R. L.; Miller, Joseph published an article in 1956, the title of the article was The SN mechanism in aromatic compounds. XXI.Computed Properties of 97-09-6 And the article contains the following content:

cf. C.A. 49, 14666e; 50, 14594h. The activating power of a series of p-SO2R groups in aromatic nucleophilic substitution is investigated and found to be in the order R = NH-, O- < NC5H10, NMe2, NMePh < Me < Ph. This order is derived by determining the rates and Arrhenius parameters of the reactions of 4,3-Cl(O2N)C6H3SO2R with MeO- in MeOH, either by direct measurement, or by computation from another reaction, assuming relative substituent effects to be constant Reactions other than with MeO- in MeOH were for R = O-, with OH- in H2O, for R = Ph, with MeO- in 1:1 (volume/volume) C6H6-MeOH. Rates and Arrhenius parameters are also reported for the reaction of 4,3-Cl(O2N)C6H3X with MeO- in MeOH for X = NO2, COMe, N2+ (estimated from the reaction of 4,3-F(O2N)C6H3N2+ with MeO-), and NMe3+ (estimated from the reaction of 4,3-Br(O2N)C6H3NMe3+ with OMe-), and activation is in the order X = N2+ > NO2 > SO2Me > NMe3+ > COMe > H. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Computed Properties of 97-09-6

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Computed Properties of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yamada, Kimiho; Shinomiya, Chiro published an article in 1959, the title of the article was Dyeing of fibers difficult to dye. VIII. Condensation-dyeing by active halo compound with free amines.Electric Literature of 97-09-6 And the article contains the following content:

By using 14 halo compounds and 15 amino compounds, the reactivity and the dyeing property for several kinds of fibers were studied. Condensation-dyeing of this system have small hue variations. Strong basic amines having conjugate systems throughout the mol. are better than the others. Halo compounds containing suitable soluble radicals are good for nylon, Vinylon, and wool, and also the one having the active halo radical at the side chain showed excellent results. Each kind of fiber is deeply dyed, but, in general, cotton is more difficult to dye than the others. Of halo compounds, the hydrolytic constant and the reactivity with benzidine in H2O are; 2-chloro-5-nitrobenzenesulfonic acid > picryl chloride > 2-chloro-3,5-dinitrobenzoic acid > 2,4-dinitrochlorobenzene > 2-chloro-4-nitrobenzenesulfonic acid > 2-chloro-4-nitrobenzoic acid > 4-chloro-3-nitrobenzenesulfonamide. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Electric Literature of 97-09-6

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Electric Literature of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Merian, Ernest published an article in 1960, the title of the article was Differentiation between alkyl aryl sulfone groups and aromatic sulfonamide groups by use of infrared spectrography.COA of Formula: C6H5ClN2O4S And the article contains the following content:

Application of infrared absorption bands to differentiate between alkyl aryl sulfone groups and primary, secondary, and tertiary aromatic sulfonamide groups was discussed. Infrared absorption spectra of the following compounds were charted: methanesulfonyl chloride; 4-methylsulfonyl-1-chloro-2-nitrobenzene; 4-methylsulfonyl-1-amino-2-chlorobenzene; a monoazo dye formed of 6-methylsulfonyl-2-diazobenzothiazole and N-ethyl-N-cyanoethyl-m-toluidine; 1-chloro-2 nitrobenzene-4-sulfonamide; 1-chloro-2-nitrobenzene-4-sulfonmethylamide; 1-chloro-2-nitrobenzene-4-sulfonethylamide; 1-amino-2-chlorobenzene-4-sulfonmethylamide; dimethylaminosulfonyl chloride; 1-chloro-2-nitrobenzene-4-sulfondiethylamide; 1-amino-2-chlorobenzene-4-sulfondimethylamide; and 1-aminobenzene-4-sulfondimethylamide. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).COA of Formula: C6H5ClN2O4S

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. COA of Formula: C6H5ClN2O4S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Chatterjee, A.; Bose, S.; Srimany, S. K. published an article in 1959, the title of the article was Constitution, stereochemistry, and synthesis of aegeline, an alkaloidal amide of Aegle marmelos.Synthetic Route of 456-12-2 And the article contains the following content:

cf. CA 47, 10544g. Aegeline (I), C18H19NO3, was shown to be N-β-hydroxy-β-p-methoxyphenylethylcinnamamide by degradation and synthesis and its trans configuration established spectrometrically. Powd. sun-dried leaves of A. marmelos (5 kg.) extracted 72 hrs. with 8 l. Et2O and the deep green extract concentrated to 500 ml., washed with 1% HCl and 5% aqueous NaOH and the dried concentrate refrigerated 2 weeks, the precipitate (3.6 g.) triturated with C6H6 and Me2CO and the residue crystallized from alc. gave I, m. 173-5°. The mother liquors evaporated and the residue chromatographed in C6H6 on 4 kg. Al2O3, the column eluted with 200 ml. EtOAc and the fraction (2.4 g.) recrystallized (alc. and EtOAc) yielded pure I, m. 176°; mono-Ac derivative, m. 124°. I (0.3 g.) in 30 ml. aldehyde-free alc. hydrogenated 2 hrs. with 0.09 g. prereduced PtO2 and the filtered solution evaporated gave dihydroaegeline, C18H21NO3, m. 140° (alc. and EtOAc). I (0.25 g.) in 10 ml. EtOAc and 2 ml. AcOH ozonized 50 min. at -75° and the ozonide decomposed reductively overnight with 0.5 g. Mg powder in 10 ml. 1:1 AcOH-H2O, the mixture diluted with 50 ml. H2O and shaken 3 times with 30 ml. CHCl3, the organic layer washed twice with 2N HCl and once with H2O and the dried (anhydrous Na2SO4) solution evaporated (N atm.), the residual oil taken up in 2 ml. alc. and treated 40 hrs. with Brady’s reagent, the precipitate taken up in 1:1 C6H6-AcOEt and chromatographed over Al2O3, eluted with C6H6 and the fraction recrystallized 3 times from alc. gave authentic 2,4-(O2N)2C6H3NHN:CHPh (II), m. 235°. I (0.15 g.) in 150 ml. MeOH treated 4 hrs. with 2 g. HIO4 and the mixture steam-distilled, the distillate (800 ml.) extracted 4 times with 250 ml. Et2O and the extract washed with aqueous NaHSO3, the iodine-free extract evaporated and the residue treated with 2,4-(O2N)2C6H3NHNH2, the precipitate (m. 225-47°) chromatographed in 15 ml. 1:1 C6H6-EtOAc over Al2O3 and eluted with 45 ml. C6H6 yielded 80 mg. II. Further elution with 30 ml. EtOAc gave 40 mg. 2,4-(O2N)2C6H3NHN:CHC6H4OMe-p (III), m. 250°. I (0.5 g.) in 5 ml. alc. and 5 ml. concentrated HCl heated 60 hrs. in a sealed tube at 120° (oil bath) and the cooled mixture diluted with 50 ml. H2O, extracted 3 times with 100 ml. Et2O and the aqueous phase evaporated, the residue decomposed with alkali and the evolved gas adsorbed in 10 ml. 2N aqueous HCl, the solution evaporated and the residue taken up in 1 ml. H2O, treated with a few drops of aqueous picric acid gave H2NMe picrate, m. 209°. The H2O-washed Et2O layer shaken with aqueous NaHCO3 and the alk. solution acidified with HCl gave 0.159 g. PhCH:CHCO2H. The acid-free Et2O evaporated and the residue taken up in 3 ml. alc., the solution treated with 2,4-(O2N)2C6H3NHNH2 and the precipitate (60 mg.) chromatographed in 10 ml. EtOAc over Al2O3 and eluted with 45 ml. C6H6 and 30 ml. EtOAc gave III from the latter eluant. I (1 g.) fused 30 min. with 6.0 g. KOH in a Ni crucible at 250° with evolution of MeNH2 and the cooled mass digested in 200 ml. H2O containing 10.0 g. NH4Cl, the filtered solution shaken 5 times with 100 ml. Et2O and the cooled aqueous solution acidified with HCl, extracted 3 times with 100 ml. Et2O and the washed and dried extract evaporated gave a mixture of 30 mg. p-MeOC6H4CO2H and 170 mg. BzOH. The probability that I suffered hydramine fission and that the basic fragment was a p-MeOC6H4CH(OH)CH2NH2 derivative was finally substantiated by a simple straight forward synthesis. Prolonged hydrolysis of ω-phthalimido-p-methoxyacetophenone with refluxing concentrated HCl gave p-MeOC6H4COCH2NH2.HCl, taken up (1 g.) in 3 ml. H2O and treated with 3 ml. aqueous solution of 1.24 g. SnCl4.4H2O containing 1 ml. HCl, the mixture stirred and the crystalline precipitate (2.0 g.) taken up in 20 ml. hot H2O, the solution cooled to 37° and stirred with 2.0 g. molten PhCH:CHCOCl, the mixture treated dropwise with 25 ml. 10% aqueous KOH until red and the stirring continued until the solution became colorless, the addition of alkali resumed and the alternate process continued until the red coloration persisted, the pyrazine-free solution stored 2 hrs. and the H2O-washed crystals recrystallized (EtOAc), gave ω-cinnamoylamino-p-methoxyacetophenone, m. 153-4°. The ketone (0.5 g.) in 50 ml. MeOH treated with 5.0 g. NaBH4 and the mixture kept 24 hrs., the solution concentrated and diluted with 100 ml. H2O, extracted 3 times with 200 ml. Et2O and the washed and dried extract evaporated yielded 60% authentic I, m. 176° (EtOAc). The absorption maximum λ 217, 223, 275 mμ (log ε 4.5328, 4.5177, 4.6053) were indicative of a trans double bond to the carboxyamide group and this assignment was in agreement with the strong absorption in the infrared spectrum at “trans-band region” (intense band at 982 cm.-1 with a shoulder at 990 cm.-1). Comparative data for other trans α,β-unsaturated amides were tabulated (compound and ν in cm.-1 given): I, 3250, 3060, 2830, 1665, 1627, 1580, 1520, 1062, 1040, 990, 982; trans-N-2-p-methoxyphenylethyl-N-methylcinnamamide, 1655, 1610, 1576, 1509, 1036, 1027, 991, 982; trans-N-methylcinnamamide, 3280, 3100, 2860, 1660, 1625, 1580, 1500, 953. I contained an asym. C atom but was optically inactive and it seemed that the linkage of the trans-cinnamoyl group to the optically active N-β-hydroxy-β-p-methoxyphenylethylamine caused an inversion at the asym. center. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Synthetic Route of 456-12-2

N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas:456-12-2) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Synthetic Route of 456-12-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Heppolette, Robert L.; Miller, Joseph published an article in 1954, the title of the article was SO2X compounds in aromatic nucleophilic substitution.Product Details of 97-09-6 And the article contains the following content:

cf. C.A. 47, 6884a. By the displacement of Cl with MeO- ion in 4-Cl 3-O2N compounds the relative reaction rates are obtained where the 1-substituent is H, 1; SO3-, 31.9; SO2NH-, 50.2; SO2NMe2, 26100; SO2Me, 52900; SO2Ph, 76000. The results show: p-SO2X groups are activating; SO2X groups are more activating than COX groups; the activating power varies with X and is parallel to that in the COX groups. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Product Details of 97-09-6

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Product Details of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Martin, R. Bruce; Edsall, John T.; Wetlaufer, Donald B.; Hollingworth, Barbara R. published an article in 1958, the title of the article was A complete ionization scheme for tyrosine and the ionization constants of some tyrosine derivatives.Application of 456-12-2 And the article contains the following content:

cf. preceding abstract Each of the 3 ionizing groups in the tyrosine mol. is characterized by 4 acidic constants (microconsts.) since the tendency of each group to accept or donate a proton depends upon the state of charge on the other 2 groups. Values for these 12 microconsts. were obtained for different ionic strengths, from spectrophotometric measurements at different pH values, from studies on the ionization of tyrosine derivatives, and from math. relations between the constants From the charge interactions between the NH4 and phenolic groups, a distance of 7.0 A. between the groups is calculated, by use of an ellipsoidal model of the type proposed by Kirkwood and Westheimer (C.A. 32, 82449). The distance between the carboxyl and phenolic protons was calculated to be 7.7 A. in the same manner. These values are compatible with those derived from mol. models, with the use of correct interatom. distances and bond angles. Tyrosine (10 g.) dissolved in about 300 ml. absolute MeOH with just enough 40% alc. NaOH, the mixture treated with about 30 ml. Mel, warmed in the dark, the precipitate dissolved by addition of just enough 40% alc. NaOH, the mixture held 2 hrs., cooled, filtered, the precipitate dissolved in H2O, adsorbed on Dowex 50-X8 (H), eluted with N NH4OH, evaporated to dryness, the residue in H2O adsorbed on Dowex 1-X8 (OH), eluted with 0.5N AcOH, the acetate salt evaporated to dryness, exchanged changed on Dowex 50, and the solution taken to dryness yielded N-trimethyltyrosine (I), m. approx. 260° (decomposition). pK values are reported for I, O-methyltyrosine, tyrosine Et ester, O-methyltyrosine Et ester, and tyrosinamide. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Application of 456-12-2

N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas:456-12-2) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Application of 456-12-2

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Dasgupta, B.; Chakravarti, R. N. published an article in 1958, the title of the article was Isolation of Aegelin.Name: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide And the article contains the following content:

cf. C.A. 51, 7328a. A modified method is described for the isolation of aegelin, N-[2-hydroxy-2-(p-methoxyphenyl)ethyl]cinnamamide (I), by extraction of Aegle marmelus Correa leaves. The leaves, 7 kg., were extracted by cold percolation with fresh 90% alc. on 6 alternate days. After distilling off the alc., the residues from 2 extractions were combined, absorbed on filter paper, dried at 80°, and extracted with Et2O in a 5-l. Soxhlet. Overconcn. in the initial extractions was prevented by funnelling Et2O between the thimble and Soxhlet wall. The extract was concentrated to 1.5 l. and refrigerated for 1 week. The precipitate was filtered off, washed with ether, recrystallized from EtOAc, dissolved in absolute alc., and refluxed 1 hr. with activated C. The solution was filtered hot and concentrated to yield I, thin colorless plates, m. 174-5°. A gel occasionally formed in the final alc. solution which could be removed by addition of excess cold alc. and filtration. Passage of alc. solution of I through Al2O3 removed the green color of some batches not decolorized by C and gave purest I, m. 178-9°. Yield of I from dried leaves is negligible during the winter and is maximum (0.2%) during June to Aug. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Name: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas:456-12-2) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Name: N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Chakravarti, R. N.; Dasgupta, B. published an article in 1958, the title of the article was Ultraviolet absorption spectra of aegelin and its derivatives.Category: amides-buliding-blocks And the article contains the following content:

A study of the spectra of aegelin (I), aegelone (II), dihydroaegelin (III), dihydroaegelone (IV) and of related simpler compounds is presented. Absolute alc. was used as a solvent in all cases except with ω-amino-p-methoxyacetophenone-HSO4 (V) with which H2O was used. Concentrations of 2-5 mg./1000 cc. were used. I shows absorption maximum at 212 (log ε 4.36), 219 (log ε 4.36), and 275 mμ (log ε 4.42). I gives trans-cinnamic acid (VI) on hydrolysis and comparison of the spectra of I, VI, trans-cinnamide, and trans-N-methylcinnamide confirmed the trans configuration of the cinnamoyl grouping in I. Other maximum and log ε values obtained were: II, 280, 4.67; V, 216-19, 4.05; 282, 4.27; III, 220, 4.22; 274, 3.78; IV, 271, 4.30. Values obtained for min. and log ε were: I, 216, 4.32; 236, 3.78; 237, 3.78; II, 2.33, 3.95; V, 217, 4.20; III, 217, 4.20; 239, 3.49; 240, 3.49; IV, 233, 3.46; 235, 3.46. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Category: amides-buliding-blocks

N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas:456-12-2) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Kulka, Marshall published an article in 1950, the title of the article was Derivatives of p-chlorobenzenesulfonic acid.Name: 3-Nitro-4-chlorobenzenesulfonamide And the article contains the following content:

In the manufacture of DDT from PhCl and Cl3CCHO (H2SO4 as condensing agent), p-ClC6H4SO3H is a byproduct; derivatives have been prepared to be tested as possible insecticides and fungicides. p-ClC6H4SO3Na (I) (335 g.) in 700 cc. CHCl3, treated (15 min.) with 370 g. ClSO3H at a rate to maintain a temperature of 60° and then heated 6 h. at 55-60°, gives 89% p-ClC6H4SO2Cl (II), b12 140°, m. 52-3°. FSO3H (200 g.) in an Al beaker, treated dropwise (3 h.) with 57 g. PhCl at 48-50° and stirred and heated an addnl. 4 h., gives 74% ClC6H4SO2F (III), m. 48-9°, and 2.5 g. (p-ClC6H4)2SO2, m. 146-7°. I (100 g.), 200 g. FSO3H, and 150 cc. CCl4, heated 24 h. at 70-5° and the acid layer heated and stirred another 24 h. with fresh CCl4, gives 85% III. III (50 g.), added (10 min.) to 125 cc. HNO3 (d. 1.5) and 50 cc. concentrated H2SO4 at 60° and heated and stirred 1.25 h. at 65°, gives 10 g. III and 67% 3-nitro-4-chlorobenzenesulfonyl fluoride, b17 165-6°, m. 51-2°; with liquid NH3 it gives 85% of the amide, m. 175-6°. III (100 g.), added to 300 g. Na2SO3 in 1000 cc. H2O at 70° and heated 5 h. at 70-80° and a few min. at 100°, gives 81% p-ClC6H4SO2H (IV), m. 98-9°; 1 mol. II, reduced at 55-60° with 2 1. 28.5% aqueous Na2SO3, gives 60% IV; 2 1. of a 31.5% solution gives 80% IV. The Na salt from 27 g. IV in 150 cc. hot EtOH and 35 g. 3,4-Cl2C6H3CH2Cl, refluxed 8 h., gives 68% p-chlorophenyl 3,4-dichlorobenzyl sulfone, m. 135-6°; p-xylylene bis(p-chlorophenyl) disulfone, m. 335-7°, 78%. IV (72 g.) and 45 g. Na2CO3 in 900 cc. H2O, added to 61 g. Cl2CHCO2H and heated 44 h. on the steam bath, give 65% p-chlorophenyl chloromethyl sulfone, m. 120-1°. III (25 g.) and 35 cc. ClCH2CH2OH, treated with 7 g. NaOH and heated 3 h. at 20-5°, give 93% 2-chloroethyl p-chlorobenzenesulfonate, b13 197°, nD20 1.5465 (II gives 47%). III (13 g.), 10 g. Cl3CCH2OH, 3 g. NaOH, and 40 cc. ether, kept 3 h. at 22-5°, give 87% 2,2,2-trichloroethyl p-chlorobenzenesulfonate, m. 73-4° (63% from II and Cl3CCH2OH on refluxing 8 h.). III and HOCH(CH2Cl)2 give 25% 1,3-dichloro-2-Pr p-chlorobenzenesulfonate (V), b14 190-200°, m. 53-4°. II (106 g.) in 50 cc. C5H5N, treated with 28 g. HOCH2CH(OH)CH2Cl (VI) (temperature below 100°) and heated 1 h. on the steam bath, give 38 g. V and 9 g. ClCH(CH2Cl)2. II (106 g.) in 50 cc. C5H5N, treated (15 min.) with 28 g. VI at 25-35°, stirred 0.5 h. at 30-5° and kept 4 h. at room temperature, give 84% 3-chloropropylene bis(p-chlorobenzenesulfonate) (VII), m. 66-7°; VII and II in C5H5N at 100° give a mixture of VI and ClCH(CH2Cl)2. 2,4-Cl2C6H3OH (16.3 g.) and 4 g. NaOH in 40 cc. H2O, treated with 19.5 g. III and heated 2 h. at 50-60°, give 85% 2,4-dichlorophenyl p-chlorobenzenesulfonate, m. 119-20°. ClCH2CH2OH (20 cc.) and 50 g. 3,4-Cl2C6H3SO2Cl (VIII), treated dropwise (0.5 h.) with 17 g. C5H5N at 10-15°, stirred an addnl. hr. at 10-15°, and kept 2 h. at 5°, give 81% 2-chloroethyl 3,4-dichlorobenzenesulfonate (IX), m. 69-70°. VIII and excess ClCH2CH2OH on refluxing give a poor yield of IX. p-ClC6H4SO2NHCH2CH2OH (X) (5 g.) and 10 g. SOCl2, refluxed 2 h., give 2 g. N-(2-chloroethyl)-p-chlorobenzenesulfonamide, m. 152-3°. II (1 mol.) in CHCl3, treated dropwise with 1 mol. amine at a temperature below 40° and then with 1 mol. aqueous NaOH, and stirred an addnl. 0.5 h., gives a nearly quant. yield of the following p-chlorobenzenesulfonamides: N,N-di-Me, m. 79-80°; N,N-di-Et, m. 37-8°; N-iso-Pr, m. 85-6°; N-Bu, m. 50-1°; X, m. 104-5°. 4-(p-Chlorophenylsulfonyl) morpholine, m. 148-9°; N,N’-bis (p-chlorophenyl-sulfonyl)-1,2-diaminopropane, m. 141-2°. II (50 g.) and a trace of Fe2(SO4)3, treated 1 h. with Cl at 175-80°, gives 63% p-C6H4Cl2 and 4 g. 1,2,3,5-C6H2Cl4. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Name: 3-Nitro-4-chlorobenzenesulfonamide

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Name: 3-Nitro-4-chlorobenzenesulfonamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Somasekhara, S.; Trivedi, B. S.; Mukherjee, S. L. published an article in 1965, the title of the article was Sulfonation of 2-hydroxybenzimidazoles.Recommanded Product: 97-09-6 And the article contains the following content:

2-Hydroxybenzimidazole (1.5 g.), 2 g. NaCl, and 9 ml. ClSO3H was heated 4 hrs. at 130-40° to yield crude 5-chlorosulfonyl-2-hydroxybenzimidazole, which was treated with 20 ml. NH3 to yield 5-sulfamoyl-2-hydroxybenzimidazole (I), m. 325-8° (decomposition) (EtOH). Similarly, 4 g. 6-chloro-2-hydroxybenzimidazole, 4 g. NaCl, and 16 ml. ClSO2OH was heated 4 hrs. at 140-50°. Treatment of the crude 6-chloro-5-chlorosulfonyl-2-hydroxybenzimidazole thus obtained with 20 ml. NH3 yielded 6-chloro-5-sulfamoyl-2-hydroxybenzimidazole, m. 301-3° (EtOH). I was also prepared as follows: 2-Nitrochlorobenzene (31.5 g.), 5.83 g. NaCl, and 93 g. ClSO3H was heated 5 hrs. at 140-50° to yield 4-chlorosulfamoyl-2-nitrochlorobenzene as a gray powder, which was treated with 50 ml. NH3. The resulting solution was clarified (C) and acidified with HOAc (pH 5.5) to obtain 15 g. 4-sulfamoyl-2-nitrochlorobenzene (II), m. 172-3° (EtOH). II (2 g.) and 4 ml. NH3 was heated 4 hrs. at 110-20° in a sealed tube to yield 4-sulfamoyl-2-nitroaniline (III), m. 204-5° (EtOH). III (1 g.) was refluxed 4 hrs. in 100 ml. 5% aqueous HOAc containing 4 g. Zn dust to yield 4-sulfamoyl-2-aminoaniline (IV), m. 165-7° (EtOH). IV (1 g.) and 2 g. urea sulfate was heated 4 hrs. at 150° in a sealed Pyrex glass tube to yield I, m. 318-21° (EtOH). The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Recommanded Product: 97-09-6

3-Nitro-4-chlorobenzenesulfonamide(cas:97-09-6) belongs to amides. Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Recommanded Product: 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics